DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8319 and CG17568

DIOPT Version :9

Sequence 1:	NP_649920.2	Gene:	CG8319 / 41165	FlyBaseID:	FBgn0037722	Length:	383	Species:	Drosophila melanogaster
Sequence 2:	NP_609951.2	Gene:	CG17568 / 35198	FlyBaseID:	FBgn0032763	Length:	513	Species:	Drosophila melanogaster

Alignment Length:	351	Identity:	88/351 - (25%)
Similarity:	138/351 - (39%)	Gaps:	55/351 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 EEYVD-GAKLAEMVKTCADVQLDPDDAMPQKMCISCVHDARTAYGFKRRCEENYKKFYLAILNGQ 87
            :|::| |..|.|...:..|:: |..|.:||:.......|:.|:   ....|.:.|...|....|
  Fly   179 QEFIDLGPILLEKNTSQLDME-DVLDELPQEELSQPRLDSTTS---PASMENDVKSEMLDSCEG- 238

  Fly    88 VIKDEPNEEDFLFIENPDKGNLEAKKKLNKEIKKTHQTASRTTKSSITTSRAGRQLRSIKNQTFK 152
                   ::|||    |..|.|            ....|..||.:::.::..    ...|.....
  Fly   239 -------DDDFL----PVDGQL------------MDLVAVATTPNTLESTAE----EKAKRGRMD 276

  Fly   153 CELCIKQFKRQINLLDHMKVHSNSHVCQNCEERFLFKADLDNHQCYRNSNSTVECPECLKVFSST 217
            ||.|.|.::.:.:...|::     ..|:..|.|  .|.|          .:|..|..|.|..||.
  Fly   277 CEKCGKVYRNRASYEKHLE-----RECRRIERR--VKVD----------KTTTTCDICNKTLSSA 324

  Fly   218 QSLDSHKCKDMQERSPFQCPHCQQAFTREQNLKAHLLIHAESKQGNGPHKCSYCQTGFFNKSALK 282
            .:|..||....|...|:.|..|.:.......|..|.|:|.||:    |.:|:.|:.||.|::.||
  Fly   325 TALKLHKEGIHQNVKPYICDSCGKQLKTITALNEHKLVHTESR----PFECTVCKAGFKNRARLK 385

  Fly   283 VHIHAHMGERPHACPFCVSNFRSKQALKVHIRIHTGEKPYQCPHCPKTFSDNNNLAKHRRRHSDE 347
            .|...| .|....|..|....::::...:|..:||.|:..:|..|...|..:..|..|...|:..
  Fly   386 AHYQIH-AEPSFVCNICGKKLQTRRTWNMHKVVHTEERRLKCDVCGALFKRSKTLKTHLLSHTGL 449

  Fly   348 RPYKCSICLQDFREKHHLKRHFLGKH 373
            |||.|:.|.:.|....:.:.|.|.||
  Fly   450 RPYVCNYCGKSFACNANCRSHKLKKH 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8319	NP_649920.2	zf-AD	4..79	CDD:285071	14/55 (25%)
		COG5048	<153..368	CDD:227381	58/214 (27%)
		C2H2 Zn finger	153..173	CDD:275368	5/19 (26%)
		C2H2 Zn finger	179..196	CDD:275368	5/16 (31%)
		C2H2 Zn finger	207..227	CDD:275370	8/19 (42%)
		C2H2 Zn finger	236..256	CDD:275368	5/19 (26%)
		C2H2 Zn finger	268..288	CDD:275368	8/19 (42%)
		C2H2 Zn finger	296..316	CDD:275368	3/19 (16%)
		zf-H2C2_2	308..332	CDD:290200	6/23 (26%)
		zf-C2H2	322..344	CDD:278523	5/21 (24%)
		C2H2 Zn finger	324..344	CDD:275368	5/19 (26%)
		C2H2 Zn finger	352..368	CDD:275368	3/15 (20%)
CG17568	NP_609951.2	zf-AD	10..87	CDD:214871
		COG5048	<313..471	CDD:227381	47/162 (29%)
		C2H2 Zn finger	314..335	CDD:275368	8/20 (40%)
		C2H2 Zn finger	343..363	CDD:275368	5/19 (26%)
		C2H2 Zn finger	371..391	CDD:275368	8/19 (42%)
		C2H2 Zn finger	398..418	CDD:275368	3/19 (16%)
		C2H2 Zn finger	426..446	CDD:275368	5/19 (26%)
		zf-H2C2_2	439..463	CDD:290200	9/23 (39%)
		C2H2 Zn finger	454..475	CDD:275368	5/20 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100