DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8319 and ZNF707

DIOPT Version :9

Sequence 1:NP_649920.2 Gene:CG8319 / 41165 FlyBaseID:FBgn0037722 Length:383 Species:Drosophila melanogaster
Sequence 2:NP_001094068.1 Gene:ZNF707 / 286075 HGNCID:27815 Length:371 Species:Homo sapiens


Alignment Length:272 Identity:86/272 - (31%)
Similarity:118/272 - (43%) Gaps:20/272 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly   120 KKTHQTASRTTKSS-------ITTS-----RAGRQLRSIKNQTFKCELCIKQFKRQINLLDHMKV 172
            ||||....|..:.|       :.|.     ||..:....|...|.|::..::..|:....:..|.
Human   105 KKTHVRRERAREGSSFRKGFRLDTDDGQLPRAAPERTDAKPTAFPCQVLTQRCGRRPGRRERRKQ 169

  Fly   173 HS--NSHVCQNCEERFLFKADLDNHQCYRNSNSTVECPECLKVFSSTQSLDSHKCKDMQERSPFQ 235
            .:  .|.:|..|.:.....:.|..||.........|||||.:.|....:|..|: |:.....||.
Human   170 RAVELSFICGTCGKALSCHSRLLAHQTVHTGTKAFECPECGQTFRWASNLQRHQ-KNHTREKPFC 233

  Fly   236 CPHCQQAFTREQNLKAHLLIHAESKQGNGPHKCSYCQTGFFNKSALKVHIHAHMGERPHACPFCV 300
            |..|.|||:.:..|..|..:|.|.:    |:.|..|...|..||.|..|...|.||||..|..|.
Human   234 CEACGQAFSLKDRLAQHRKVHTEHR----PYSCGDCGKAFKQKSNLLRHQLVHTGERPFYCADCG 294

  Fly   301 SNFRSKQALKVHIRIHTGEKPYQCPHCPKTFSDNNNLAKHRRRHSDERPYKCSICLQDFREKHHL 365
            ..||:|:.|..|.|:|:|||||.|..|.|:|......:.|||.|..:|.|:|..|.:.||.....
Human   295 KAFRTKENLSHHQRVHSGEKPYTCAECGKSFRWPKGFSIHRRLHLTKRFYECGHCGKGFRHLGFF 359

  Fly   366 KRHFLGKHRDGD 377
            .|| ...||.|:
Human   360 TRH-QRTHRHGE 370

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8319NP_649920.2 zf-AD 4..79 CDD:285071
COG5048 <153..368 CDD:227381 70/216 (32%)
C2H2 Zn finger 153..173 CDD:275368 3/19 (16%)
C2H2 Zn finger 179..196 CDD:275368 3/16 (19%)
C2H2 Zn finger 207..227 CDD:275370 7/19 (37%)
C2H2 Zn finger 236..256 CDD:275368 7/19 (37%)
C2H2 Zn finger 268..288 CDD:275368 7/19 (37%)
C2H2 Zn finger 296..316 CDD:275368 8/19 (42%)
zf-H2C2_2 308..332 CDD:290200 12/23 (52%)
zf-C2H2 322..344 CDD:278523 8/21 (38%)
C2H2 Zn finger 324..344 CDD:275368 7/19 (37%)
C2H2 Zn finger 352..368 CDD:275368 4/15 (27%)
ZNF707NP_001094068.1 KRAB 8..68 CDD:214630
KRAB 8..47 CDD:279668
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 71..143 9/37 (24%)
C2H2 Zn finger 178..198 CDD:275368 5/19 (26%)
COG5048 <187..366 CDD:227381 66/184 (36%)
C2H2 Zn finger 206..226 CDD:275368 8/20 (40%)
zf-H2C2_2 218..242 CDD:290200 9/24 (38%)
C2H2 Zn finger 234..254 CDD:275368 7/19 (37%)
zf-C2H2 260..282 CDD:278523 7/21 (33%)
C2H2 Zn finger 262..282 CDD:275368 7/19 (37%)
zf-H2C2_2 274..299 CDD:290200 10/24 (42%)
C2H2 Zn finger 290..310 CDD:275368 8/19 (42%)
zf-H2C2_2 302..325 CDD:290200 12/22 (55%)
C2H2 Zn finger 318..338 CDD:275368 7/19 (37%)
C2H2 Zn finger 346..366 CDD:275368 6/20 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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