DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8319 and LOC100911196

DIOPT Version :9

Sequence 1:	NP_649920.2	Gene:	CG8319 / 41165	FlyBaseID:	FBgn0037722	Length:	383	Species:	Drosophila melanogaster
Sequence 2:	XP_006228368.1	Gene:	LOC100911196 / 100911196	RGDID:	6494165	Length:	1059	Species:	Rattus norvegicus

Alignment Length:	232	Identity:	72/232 - (31%)
Similarity:	105/232 - (45%)	Gaps:	11/232 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   149 QTFKCELCIKQFKRQINLLDHMKVH--SNSHVCQNCEERFLFKADLDNHQCYRNSNSTVECPECL 211
            :.|.|..|.:.||..:.|:.|..||  ..:..|..|.:.|....||..|:..........||.|.
  Rat   790 ERFSCATCGQSFKHFLGLVTHKYVHLVRRTLGCGLCGQSFAGAYDLLLHRRSHRQKRGFRCPVCG 854

  Fly   212 KVFSSTQSLDSH-KCKDMQERSPFQCPHCQQAFTREQNLKAHLLIHAESKQGNGPHKCSYCQTGF 275
            |.|.....|..| :|.  .|:.|::|..|.:.|.|...|:.|.::|.    |....||..|...|
  Rat   855 KRFWEAALLMRHQRCH--TEQRPYRCGVCGRGFLRSWYLRQHRVVHT----GERAFKCGVCAKHF 913

  Fly   276 FNKSALKVHIHAHMGERPHACPFCVSNFRSKQALKVHIRIHTGEKPYQCPHCPKTFSDNNNLAKH 340
            ...|:|..|...|...||..|..|...||.:..|..|.|:|.||:.|:|.||.|.|...:::.:|
  Rat   914 AQSSSLAEHRRLHAVARPQRCGACGKTFRYRSNLLEHQRLHLGERAYRCEHCGKGFFYLSSVLRH 978

  Fly   341 RRRHSDERP-YKCSICLQDFREKHHLKRHFLGKHRDG 376
            :|.|...|| .:|..||:.|::..:.::| |..|:.|
  Rat   979 QRAHEPPRPELRCPACLKAFKDPGYFRKH-LAAHQGG 1014

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8319	NP_649920.2	zf-AD	4..79	CDD:285071
		COG5048	<153..368	CDD:227381	67/218 (31%)
		C2H2 Zn finger	153..173	CDD:275368	6/19 (32%)
		C2H2 Zn finger	179..196	CDD:275368	5/16 (31%)
		C2H2 Zn finger	207..227	CDD:275370	8/20 (40%)
		C2H2 Zn finger	236..256	CDD:275368	6/19 (32%)
		C2H2 Zn finger	268..288	CDD:275368	6/19 (32%)
		C2H2 Zn finger	296..316	CDD:275368	7/19 (37%)
		zf-H2C2_2	308..332	CDD:290200	11/23 (48%)
		zf-C2H2	322..344	CDD:278523	8/21 (38%)
		C2H2 Zn finger	324..344	CDD:275368	7/19 (37%)
		C2H2 Zn finger	352..368	CDD:275368	4/15 (27%)
LOC100911196	XP_006228368.1	PHA03378	<163..>349	CDD:223065
		C2H2 Zn finger	222..242	CDD:275368
		C2H2 Zn finger	250..270	CDD:275368
		COG5048	349..>421	CDD:227381
		C2H2 Zn finger	352..372	CDD:275368
		C2H2 Zn finger	380..400	CDD:275368
		C2H2 Zn finger	409..429	CDD:275368
		C2H2 Zn finger	441..461	CDD:275370
		C2H2 Zn finger	548..568	CDD:275368
		zf-H2C2_2	561..584	CDD:404364
		C2H2 Zn finger	576..596	CDD:275368
		C2H2 Zn finger	604..624	CDD:275368
		C2H2 Zn finger	666..686	CDD:275368
		C2H2 Zn finger	694..714	CDD:275368
		C2H2 Zn finger	794..814	CDD:275368	6/19 (32%)
		C2H2 Zn finger	822..842	CDD:275368	6/19 (32%)
		C2H2 Zn finger	850..870	CDD:275368	7/19 (37%)
		C2H2 Zn finger	878..898	CDD:275368	6/19 (32%)
		C2H2 Zn finger	906..926	CDD:275368	6/19 (32%)
		C2H2 Zn finger	934..954	CDD:275368	7/19 (37%)
		C2H2 Zn finger	962..982	CDD:275368	7/19 (37%)
		C2H2 Zn finger	991..1011	CDD:275368	6/20 (30%)
		C2H2 Zn finger	1019..1039	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24390
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100