Protein Alignment CG8312 and Nos1ap

DIOPT Version :9

• Sequence 1: NP_649918.1
• Gene: CG8312 / 41163
• FlyBaseID: FBgn0037720
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_001103455.1
• Gene: Nos1ap / 70729
• MGIID: 1917979
• Length: 503
• Species: Mus musculus
• Alignment Length: 481
• Identity: 96/481 - (19%)
• Similarity: 154/481 - (32%)
• Gaps: 151/481 - (31%)

  Fly   133 LARLLGNTYN-AKKFEKQEQKRLASGSEGGKFNTYSGRRGRAGPYLERFKRVSKEDGDVAGEDDT 196
            :.|.:|..:. ..|...|..::.|.|.|.|:....|...|..|..|...:|||    ..|.|:..
Mouse   152 IVRTVGQAFEVCHKLSLQHTQQNADGQEDGESERNSDGSGDPGRQLTGAERVS----TAAAEETD 212

  Fly   197 VRVTNVITLTTDSRDLLYGSR----QEHVGRTGG---------YDQNDQLTSKAYRTLTRSLGKL 248
            :   :.:.:.....|:|..||    .:.||:.||         :.|...||:.....|
Mouse   213 I---DAVEVPLPGNDILEFSRGVTDLDAVGKDGGSHIDSTVSPHPQEPMLTASPRMLL------- 267

  Fly   249 WRRTHSVDISTPDPEFKVSYLGNVLTGWAKAGEGCVEKQLNTLWRNYTQHSKPDVIMRLKVCASG 313
                       |....|...||   ||...:    ...|:..|.:...|..:...:
Mouse   268 -----------PSSSSKPPGLG---TGTPLS----THHQMQLLQQLLQQQQQQTQV--------- 305

  Fly   314 LKATTRQHGLTEYWAHRITYCCAPKNYPRVFCWIYRHEGRKLKHELRCHAVLCSKEKIAQDICDT 378
              |..:.|.|.:..|                    .....:|:.:.|.|.:|...:.:.|.|...
Mouse   306 --AVAQVHLLKDQLA--------------------AEAAARLEAQARVHQLLLQNKDMLQHISLL 348

  Fly   379 LRENLESALREFKREKILKQNARLSLANAVYDNPSLPRRKIMLSVGGNNYRPPLE---RSKSAPK 440
            :::..|..|             :||..|.:....||                 ||   ||.:.|.
Mouse   349 VKQVQELEL-------------KLSGQNTMGSQDSL-----------------LEITFRSGALPV 383

  Fly   441 LMAIEEAIGEEEGDEIEDTNEPEMMPCCQKDSLYPA-MTLGRRRCRRGHSIRRTGKIQSFSPCCS 504
            |.       |....:.||.:.| ::.....|..:|| ..|||..|        ..|::.|
Mouse   384 LC-------ESTTPKPEDLHSP-LLGAGLADFAHPAGSPLGRHDC--------LVKLECF----- 427

  Fly   505 SHMAKELPQEETKTMAAAGSSANDGSDSDDFEKLLKF-DTTLSNELLPYFDMQLHKNSSQSMVSL 568
                :.||.|:|:.|.|.|.....|.:      |:|| ::.:::|        ...|:.:|....
Mouse   428 ----RFLPPEDTQPMMAQGEPLLGGLE------LIKFRESGIASE--------YESNTDESEERD 474

  Fly   569 SELKEEEGEPLSLLPTINSDPSADPE 594
            |..:||....|::|.......|.|.|
Mouse   475 SWSQEELPRLLNVLQRQELGDSLDDE 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8312	NP_649918.1	PID_2	263..442	CDD:373244	30/181 (17%)
Nos1ap	NP_001103455.1	PTB_CAPON-like	2..180	CDD:269968	6/27 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	170..212		13/45 (29%)
		Interaction with NOS1. /evidence=ECO:0000250	491..503		3/10 (30%)
		PDZ-binding. /evidence=ECO:0000250	501..503		96/481 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831092
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840