Protein Alignment CG8312 and numbl

DIOPT Version :10

• Sequence 1: NP_649918.1
• Gene: CG8312 / 41163
• FlyBaseID: FBgn0037720
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: XP_005173435.1
• Gene: numbl / 497616
• ZFINID: ZDB-GENE-051113-340
• Length: 640
• Species: Danio rerio
• Alignment Length: 379
• Identity: 75/379 - (19%)
• Similarity: 123/379 - (32%)
• Gaps: 108/379 - (28%)

  Fly   264 FKVSYLGNVLTGWAKAGEGCVE--KQLNTLWRNYTQHSKPDVIMRLKVCASGLKAT--TRQHGLT 324
            |.|.|||.|....::....|.|  |:|..       ..|..|...|.|.|.||:..  ..:..:.
Zfish    61 FPVRYLGLVEVDESRGMHVCEEAVKKLKV-------SGKKTVKAVLWVSADGLRVVDDKTKDLIV 118

  Fly   325 EYWAHRITYCCAPKNYPRVFCWIYR----------------HEGRKLKHELRCHAVLCSKEK--- 370
            :....::::|...:||.:.|.:|.|                ..|.:|.|.:.|....|.:.|
Zfish   119 DQTIEKVSFCAPDRNYDKAFSYICRDGTTRRWMCHCFMALKDSGERLSHAVGCAFAACLERKQRR 183

  Fly   371 -------IAQDICDT--LRE---NLESALREFKREKILKQNARLSLANAVYDNPSLPRRKIMLSV 423
                   .:.|...|  :||   .:.||.::..||.|:||         :.|     ::|.|..:
Zfish   184 EKECGVTASFDASRTSFVREGSFRVSSAAQQSDREDIMKQ---------IQD-----KKKEMCGI 234

  Fly   424 GG---NNYRPPLERSKSAPKLMAIEEAIGEEEGDEIEDTNEPEMMPCCQKDSLYPAMTLGRRRCR 485
            ..   .|..||              |..| ..|:..| ...|..:|               ||..
Zfish   235 SALPPGNASPP--------------EGAG-SPGERAE-PGGPHAIP---------------RRHA 268

  Fly   486 RGHSIRRTGKIQSFSPCCSSHMAKELPQEETKTMAAAGSSANDGSDS----DDFE---KLLKFDT 543
            ....:.|.|..:.|         .:|.|:.:..........||...:    .||:   .:.:.|.
Zfish   269 PIEQLVRQGSFRGF---------PQLSQKNSPFKRQLSLRLNDLPSTLQRKTDFQTKNPVPEMDL 324

  Fly   544 TLSNEL--LPYFDMQLHKNSSQSMVSLSELKEEEGEPLSLLPTINSDPSADPEA 595
            |::.|.  :.....|::.:.::....|.........|:|..|.....|.|.|:|
Zfish   325 TVAGEADSINALCSQINSSFTKPSEDLCAKTTNNCLPISCAPPAIPPPPAPPQA 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8312	NP_649918.1	PID_2	263..442	CDD:405418	46/215 (21%)
numbl	XP_005173435.1	PTB_Numb	45..179	CDD:241298	28/124 (23%)
		NumbF	260..344	CDD:461874	17/107 (16%)