Protein Alignment CG8312 and ced-6

DIOPT Version :9

• Sequence 1: NP_649918.1
• Gene: CG8312 / 41163
• FlyBaseID: FBgn0037720
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_001246225.1
• Gene: ced-6 / 35971
• FlyBaseID: FBgn0029092
• Length: 533
• Species: Drosophila melanogaster
• Alignment Length: 690
• Identity: 122/690 - (17%)
• Similarity: 205/690 - (29%)
• Gaps: 248/690 - (35%)

  Fly   105 TPATTAAPLPPVPIGTPPRQHKFVKSNSLARL-LGNTYNAKKFEKQEQKRLASGSEGGKFNTYSG 168
            |..||..|..|...|......|  .:..:|:| ..|..|:.|  :|:|.:....::||. ||..|
  Fly    11 TAPTTTMPYQPANSGGTSGGSK--AAAKMAQLKFWNKQNSSK--QQQQDKDKDAADGGN-NTSGG 70

  Fly   169 RRGRAGPYLERFKRVSKEDGDVAGEDDTVRVTNVITLTTDSRDLLYGSRQEHVGRTGGYDQNDQL 233
            ..|            |..:||...|...                         |:.......:||
  Fly    71 GTG------------SNSNGDAKSEAKN-------------------------GKRNWLHTPEQL 98

  Fly   234 TSKAYRTLTRSLGKLWRRTHSVDISTPDPEFKVSYLGNVLTGWAKAGEGCVEKQLNTLWRNYTQH 298
            .|                .|:|        :.|.:.||:.....| |...|::.:..|  .:.|.
  Fly    99 IS----------------GHAV--------YLVKFFGNLSVDQPK-GIEVVKEAIRKL--QFAQQ 136

  Fly   299 SK------PDVIMRLKVCASGLKATTRQHGLTEYWAHR-----ITYCCAPKNYPRVFCWIYR--- 349
            .|      .:...:|::..| :|....|...|....|:     |:||...|...:.|.:|.:
  Fly   137 MKKAETGTQEKFKKLEITIS-IKGVAIQEPRTHKILHQFPLYNISYCADEKGVKKFFSFIAKTVK 200

  Fly   350 -HEG----------------RKLKHELRCHAVLCSKEKIAQDICDTLRENLESALREF------- 390
             .:|                .|::....|...:  ..|:|.||..|:.:..:.|.|::
  Fly   201 TQDGSDPTSNGHANGNGDGSAKVEESHECFVFI--SNKLASDITLTIGQAFDLAYRKYMDSTEKT 263

  Fly   391 KREKILKQNARLSLANAVYD------NPSLPRRKIMLSVGGNNYRPPLERSKSAPK--LMAIEEA 447
            ...|..:|...|.....||.      :..||:.::...:.....:..||...:.|:  :....||
  Fly   264 NLSKAQQQINHLQQTVNVYKERLREVSAKLPKAELDALLFNLGIKDILEAPTTEPQNGIEVASEA 328

  Fly   448 IGEEEGDE---IEDTNEPEMMPCCQKDSLYPAMTLGRRRCRRGHSIRRTGKIQSFSPCCSSHMAK 509
            :...:.|:   :.|||.                              .|....|.||  ||.:..
  Fly   329 LSNGKLDDDKLLIDTNS------------------------------TTASTHSASP--SSFLPI 361

  Fly   510 ELPQEETKTMAAAGSSANDGSDSDDFEKLLKFDTTLSNELLPYFDMQLHKNSSQSMVSLSELKEE 574
            ..|:....:..:.|..:|.          .|.|..|.|.
  Fly   362 VPPRNNLSSQISIGGKSNS----------QKMDELLLNS-------------------------- 390

  Fly   575 EGEPLSLLPTINSDPSADPEADYNAEDHDVTAPRRSGVC---------SDGEEDFLDDADDHYFR 630
                       :||...||.||   |..::....||.:.         |.|:..|.::.|
  Fly   391 -----------DSDSDFDPRAD---ETQEIGGTGRSAISNMFGFEPANSFGQHLFSNNND----- 436

  Fly   631 HAAMLTMLHRSSMRKMRAADQTSLKYRHQTQSSISSNASSSTTASTSAAAGGGSAQQGLTSPDSD 695
                                       |:.|::.||...:|...|.:::  |.|::..:|.|...
  Fly   437 ---------------------------HKLQNNNSSLLITSNNNSINSS--GFSSELNITPPLLA 472

  Fly   696 EGSISSGCETASTVTNANHEEYNSKRV-SDPGQLEQSPDL 734
            .....:.....::||..|....|:... |||.:|...|::
  Fly   473 PPPKIAAPRRLNSVTTGNGLNGNTDLFGSDPFELNNGPNI 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8312	NP_649918.1	PID_2	263..442	CDD:373244	41/224 (18%)
ced-6	NP_001246225.1	PTB_CED-6	92..261	CDD:269971	36/198 (18%)
		AceK	233..>304	CDD:295079	14/72 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438629
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11232
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940