Protein Alignment CG8312 and Mapk8ip2

DIOPT Version :9

• Sequence 1: NP_649918.1
• Gene: CG8312 / 41163
• FlyBaseID: FBgn0037720
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_001094190.1
• Gene: Mapk8ip2 / 315220
• RGDID: 1309727
• Length: 835
• Species: Rattus norvegicus
• Alignment Length: 502
• Identity: 101/502 - (20%)
• Similarity: 159/502 - (31%)
• Gaps: 191/502 - (38%)

  Fly   429 RPPLERSKSAPKLMAIEEAIGEEEGDEIEDTNEPEMMPC----------CQKDSLYPAMTLGRRR 483
            |||.:        :::|| ..:|:..||.|       .|          |:||||    :||  |
  Rat    22 RPPQD--------ISLEE-FDDEDLSEITD-------DCGLGLSYDSDHCEKDSL----SLG--R 64

  Fly   484 CRRGHSIRRTGKIQSFSPCCSSHMAKELPQEETKTMAAAGSSANDGSDSDDFEKLLKFDTTLSNE 548
            ..:.|            |.||.                          .|||::
  Rat    65 SEQPH------------PICSF--------------------------QDDFQE----------- 80

  Fly   549 LLPYFDMQLHKNSSQSMVSLSELKEEE-------------------GEPLSLLPTINSDPSADPE 594
                |:| :..|..:......|.:|||                   ||  ||:|:    ||.:
  Rat    81 ----FEM-IDDNEEEEDEEEEEEEEEEEDGDGDGRAGGGSGSQELSGE--SLIPS----PSIE-- 132

  Fly   595 ADYNAEDHDVTAPRRSGVCSDGEEDFLDDADDHYFRHA-------AMLTMLHRSSMRKMRAADQT 652
                 |.|.: .|....:.:.|.:|.|::..:..|..|       .:|....:..::::.|....
  Rat   133 -----ESHKL-RPTTLHLTTLGAQDSLNNNSNGGFTSAPPSSWQETVLRSPVQEPLKELPAPLLP 191

  Fly   653 SLKYRHQTQSSISSNASSSTTASTSAAAGGGSAQQGLTSPDSDEG------SISSGCETASTVTN 711
            :.:..|:.||.................|.||:      ||.||.|      |.|||
  Rat   192 AEEEHHEVQSLARPGCDCEGNQPPEPPASGGA------SPSSDPGIEADLRSHSSG--------- 241

  Fly   712 ANHE-EYNSKRVSDPGQLEQSPDLELEQAQVLEQMMIYQRLEQQLRKNSGDATNYSSSSSITLKR 775
             .|| ..:|:.:|.||    |...|...|::...:......|.:|..:||.::..||..:.:::.
  Rat   242 -GHEGRRSSQELSSPG----SDSEEAGGARLGRMISSISETELELSSDSGSSSGRSSHLTNSIEE 301

  Fly   776 SNSGSDKQERSDHPD----------------DDNSDSDESGYVEFQEKERPGQQP---------L 815
            ::|.:.:.|....|:                ||.:...|||.....:.......|         :
  Rat   302 ASSPASEPEPEPEPEPLHEPPRRPAFLPVGQDDTNSEYESGSESEPDLSEDADSPWLLSNLVSRM 366

  Fly   816 ISEASVTLAKIATVKPQVPPKPAPRRSLSLNAVATGASAGSSAGKAP 862
            |||.|             .|...|.:.||..|......|.|.|...|
  Rat   367 ISEGS-------------SPIRCPGQCLSPPAPRPPEEAASQANPVP 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8312	NP_649918.1	PID_2	263..442	CDD:373244	3/12 (25%)
Mapk8ip2	NP_001094190.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..26		3/3 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	44..357		78/406 (19%)
		JNK-binding domain (JBD). /evidence=ECO:0000250|UniProtKB:Q9ERE9	111..278		41/200 (21%)
		Necessary for interaction with FGF13. /evidence=ECO:0000250|UniProtKB:Q13387	242..509		37/176 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	369..509		11/45 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	544..579
		SH3_JIP2	619..673	CDD:212875
		PTB_JIP	690..835	CDD:269923

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334806
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930