Protein Alignment CG8312 and Numb

DIOPT Version :10

• Sequence 1: NP_649918.1
• Gene: CG8312 / 41163
• FlyBaseID: FBgn0037720
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: XP_063117648.1
• Gene: Numb / 29419
• RGDID: 620107
• Length: 659
• Species: Rattus norvegicus
• Alignment Length: 568
• Identity: 107/568 - (18%)
• Similarity: 173/568 - (30%)
• Gaps: 208/568 - (36%)

  Fly   249 WRRTHSVDISTPDPEFKVSYLGNVLTGWAKAGEGCVEKQLNTLWRNYTQHSKPDVIMRLK----- 308
            | :|....:.|....|.|.|||:|....::.                 .|...|.:.|||
  Rat    32 W-QTDEEGVRTGKCSFPVKYLGHVEVDESRG-----------------MHICEDAVKRLKAERKF 78

  Fly   309 ------------------VCASGLKATTRQHG--LTEYWAHRITYCCAPKNYPRVFCWIYR---- 349
                              |.|.||:....:..  :.:....::::|...:|:.|.|.:|.|
  Rat    79 FKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTT 143

  Fly   350 ------------HEGRKLKHELRCHAVLCSKEKIAQD----ICDTL--------RE---NLESAL 387
                        ..|.:|.|.:.|....|.:.|..::    :..|.        ||   .:.:|.
  Rat   144 RRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTATFDASRTTFTREGSFRVTTAT 208

  Fly   388 REFKREKILK--QNARLSLANAVYDNPSLPRRKIMLSVGGNNYRPPLERSKSAPKLMAIEEAIGE 450
            .:.:||:|:|  |:|:    .|..|....|      ||...|..|    |.|:|....::.....
  Rat   209 EQAEREEIMKQLQDAK----KAETDKTVGP------SVAPGNSAP----SPSSPTSPTLDPTASL 259

  Fly   451 EEGDEIEDTNEPEMMPCCQKDSLYPAMTLGRRRCRRGHSIRRTGKIQSFSPCCSSHMAKELPQEE 515
            |       .|.|..:|               ||......:.|.|..:.| |..|
  Rat   260 E-------MNNPHAIP---------------RRHAPIEQLARQGSFRGF-PALS----------- 290

  Fly   516 TKTMAAAGSSANDGSDSDDFEKLLKFDTTLS---NELLPYFDMQLHKNSSQSMVSLSELKEEEGE 577
                                :|:..|...||   |||                .|..:.|.:
  Rat   291 --------------------QKMSPFKRQLSLRINEL----------------PSTMQRKTD--- 316

  Fly   578 PLSLLPTINSDPSADPEADYNAEDHDVTAPRRSGVCSDGEEDFLDDADDHYFRHAAM---LTMLH 639
                .|..|:.|..:.||:           ..|.:||.....|....:|. |..|.|   :|::
  Rat   317 ----FPIKNTVPEVEGEAE-----------SISSLCSQITSAFSTPCEDP-FSSAPMTKPVTLV- 364

  Fly   640 RSSMRKMRAADQTSLKYRHQTQSSIS-SNASSSTTASTSAAAGGGSAQQGLTSPDS---DEGSIS 700
                     |.|:.:...:.|.|::. ..|..::||....|...........:||:   :..:|.
  Rat   365 ---------APQSPVLQANGTDSALHVLTAKPASTALAPVAMPVRETNPWAHAPDAANKEIAAIH 420

  Fly   701 SGCETAST-------VTNANHEEYNSKRVSDPGQLEQSPDLELEQAQV 741
            ||.|...:       :..|.|....|:  :|....|.|..:..:|.||
  Rat   421 SGTEWGQSSGAASPGLFQAGHRRTPSE--ADRWLEEVSKSVRAQQPQV 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8312	NP_649918.1	PID_2	263..442	CDD:405418	47/236 (20%)
Numb	XP_063117648.1	None