Protein Alignment CG8312 and Numb

DIOPT Version :9

• Sequence 1: NP_649918.1
• Gene: CG8312 / 41163
• FlyBaseID: FBgn0037720
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: XP_006515635.2
• Gene: Numb / 18222
• MGIID: 107423
• Length: 740
• Species: Mus musculus
• Alignment Length: 456
• Identity: 85/456 - (18%)
• Similarity: 149/456 - (32%)
• Gaps: 159/456 - (34%)

  Fly   218 QEHVG---RTGGYDQNDQLTSKAYRTLTRSLGKLWRRTHSV---DISTP-----DPE-------- 263
            |.|:.   .|||...::..:.:..:.....|.:.:||...|   :.|.|     |.|
Mouse    61 QSHIATDWSTGGPQSSNTFSRQVVKVNMNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCS 125

  Fly   264 FKVSYLGNVLTGWAKAGEGCVEKQLNTLWRNYTQHSKPDVIMRLK-------------------- 308
            |.|.|||:|....::.                 .|...|.:.|||
Mouse   126 FPVKYLGHVEVDESRG-----------------MHICEDAVKRLKAERKFFKGFFGKTGKKAVKA 173

  Fly   309 ---VCASGLKATTRQHG--LTEYWAHRITYCCAPKNYPRVFCWIYR----------------HEG 352
               |.|.||:....:..  :.:....::::|...:|:.|.|.:|.|                ..|
Mouse   174 VLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTRRWICHCFMAVKDTG 238

  Fly   353 RKLKHELRCHAVLCSKEKIAQD----ICDTL--------RE---NLESALREFKREKILK--QNA 400
            .:|.|.:.|....|.:.|..::    :..|.        ||   .:.:|..:.:||:|:|  |:|
Mouse   239 ERLSHAVGCAFAACLERKQKREKECGVTATFDASRTTFTREGSFRVTTATEQAEREEIMKQLQDA 303

  Fly   401 RLSLANAVYDNPSLPRRKIMLSVGGNNYRPPLERSKSAPKLMAIEEAIGEEEGDEIEDTNEPEMM 465
            :.:..:.....||:        ..||....|...:...|            :|....:.|.|..:
Mouse   304 KKAETDKTVVGPSV--------APGNTAPSPSSPTSPTP------------DGTASSEMNNPHAI 348

  Fly   466 P--------CCQKDSL--YPAMTLGRRRCRRGHSI----------RRT------------GKIQS 498
            |        ..::.|.  :||::......:|..|:          |:|            |:.:|
Mouse   349 PRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINELPSTMQRKTDFPIKNTVPEVEGEAES 413

  Fly   499 FSPCCSS-HMAKELPQEE-------TK--TMAAAGSSANDGSDSDDFEKLL---KFDTTLSNELL 550
            .|..||. ..|...|.|:       ||  |:.|..|.....:.:|....:|   ..:|.|::..:
Mouse   414 ISSLCSQITSAFSTPSEDPFSSAPMTKPVTLVAPQSPVLQANGTDSASHVLTAKPANTALAHVAM 478

  Fly   551 P 551
            |
Mouse   479 P 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8312	NP_649918.1	PID_2	263..442	CDD:373244	44/244 (18%)
Numb	XP_006515635.2	PTB_Numb	110..255	CDD:241298	28/161 (17%)
		NumbF	347..425	CDD:368837	13/77 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831090
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840