Protein Alignment CG8312 and FAM43B

DIOPT Version :9

• Sequence 1: NP_649918.1
• Gene: CG8312 / 41163
• FlyBaseID: FBgn0037720
• Length: 866
• Species: Drosophila melanogaster
• Sequence 2: NP_997217.1
• Gene: FAM43B / 163933
• HGNCID: 31791
• Length: 329
• Species: Homo sapiens
• Alignment Length: 288
• Identity: 86/288 - (29%)
• Similarity: 128/288 - (44%)
• Gaps: 64/288 - (22%)

  Fly   245 LGKLWR-RTHSVDISTPDPEFKVSYLGNVLTGWAKAGEGCVEKQLNTLWRNYTQHSKPDVIMRLK 308
            ||:::| |...|:::..||.:.|.||||.:|..|| |:||.:..:..:|..
Human    52 LGRVFRSRRQKVELNKEDPTYTVWYLGNAVTLHAK-GDGCTDDAVGKIWAR-------------- 101

  Fly   309 VCASG----LKATTRQHGLT-------------------EYWAHRITYCCAPKNYPRVFCWIYRH 350
             |..|    :|.|...||:.                   .|...|||||.|...:||||.|:|||
Human   102 -CGPGGGTKMKLTLGPHGIRMQPCERSAAGGSGGRRPAHAYLLPRITYCTADGRHPRVFAWVYRH 165

  Fly   351 EGRKLKHELRCHAVLCSKEKIAQDICDTLRENLESALREFKREKILKQNAR------LSLANAVY 409
            :.|.....|||||||.::...|:.:...||:...:|..:|||.: .:.:||      |....|..
Human   166 QARHKAVVLRCHAVLLARAHKARALARLLRQTALAAFSDFKRLQ-RQSDARHVRQQHLRAGGAAA 229

  Fly   410 DNPSLPRRKIMLSVGGNNYR-PPLERSKSAPKLMAIEEAIGEEEGDEIED-------TNEPEMM- 465
            ..|..|.|:::.:...  || ||.|||:.||:|.:|:|...|||.|:.|:       ...||::
Human   230 SVPRAPLRRLLNAKCA--YRPPPSERSRGAPRLSSIQEEDEEEEEDDAEEQEGGVPQRERPEVLS 292

  Fly   466 ------PCCQKDSLYPAMTLGRRRCRRG 487
                  .|..:.:..|......||.:.|
Human   293 LARELRTCSLRGAPAPPPPAQPRRWKAG 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8312	NP_649918.1	PID_2	263..442	CDD:373244	64/208 (31%)
FAM43B	NP_997217.1	PH-like	71..263	CDD:418428	65/210 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	245..329		24/78 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141139
Domainoid	1	1.000	111	1.000	Domainoid score	I6245
eggNOG	1	0.900	-	-		E1_KOG4448
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003422
OrthoInspector	1	1.000	-	-		otm40360
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11232
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5446
SonicParanoid	1	1.000	-	-		X2312
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.870