DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment P58IPK and Dnaja3

DIOPT Version :9

Sequence 1:	NP_649916.1	Gene:	P58IPK / 41161	FlyBaseID:	FBgn0037718	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	NP_076135.3	Gene:	Dnaja3 / 83945	MGIID:	1933786	Length:	480	Species:	Mus musculus

Alignment Length:	157	Identity:	56/157 - (35%)
Similarity:	77/157 - (49%)	Gaps:	43/157 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   352 LLGTEMYDDAIHSFQAALDLEESNTRAKEGIQRAKKLQKQSERRDYYKILGVKRSASKQEIVKAY 416
            |.||:.:     .|........|.:.||:               |||:||||.|:||:::|.|||
Mouse    69 LTGTKSF-----PFVCTTSFHTSASLAKD---------------DYYQILGVPRNASQKDIKKAY 113

  Fly   417 RKAAQKWHPDNFRDEEKKVAEKKFIDIAAAKEVLTDPEKRRQFD----NGEDPLDPESNQ---RG 474
            .:.|:|:|||..:|:.|  |::||..:|.|.|||:|..||:|:|    .|.||....|.|   ||
Mouse   114 YQLAKKYHPDTNKDDPK--AKEKFSQLAEAYEVLSDEVKRKQYDAYGSAGFDPGTSSSGQGYWRG 176

  Fly   475 G-----------FHGE---HPFGHFQH 487
            |           ..||   .|||.||:
Mouse   177 GPSVDPEELFRKIFGEFSSSPFGDFQN 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
P58IPK	NP_649916.1	TPR_11	42..108	CDD:290150
		TPR repeat	43..71	CDD:276809
		TPR repeat	76..106	CDD:276809
		TPR_11	78..142	CDD:290150
		TPR repeat	111..139	CDD:276809
		TPR_1	113..144	CDD:278916
		TPR_19	167..234	CDD:291240
		TPR repeat	190..220	CDD:276809
		TPR repeat	225..253	CDD:276809
		TPR repeat	309..337	CDD:276809
		TPR_11	312..373	CDD:290150	4/20 (20%)
		TPR repeat	341..371	CDD:276809	4/18 (22%)
		TPR repeat	376..399	CDD:276809	4/22 (18%)
		DnaJ	395..>485	CDD:223560	47/110 (43%)
		DnaJ	396..460	CDD:278647	33/63 (52%)
Dnaja3	NP_076135.3	DnaJ	90..480	CDD:223560	51/131 (39%)
		DnaJ	93..155	CDD:278647	33/63 (52%)
		DnaJ_C	207..416	CDD:199909
		DnaJ_zf	236..296	CDD:199908
		CXXCXGXG motif	236..243
		CXXCXGXG motif	253..260
		CXXCXGXG motif	275..282
		CXXCXGXG motif	289..296
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	437..468
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910