Protein Alignment P58IPK and XB22063322

DIOPT Version :10

• Sequence 1: NP_649916.1
• Gene: P58IPK / 41161
• FlyBaseID: FBgn0037718
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: XP_002944642.2
• Gene: XB22063322 / 734020
• XenbaseID: XB-GENE-22063323
• Length: 495
• Species: Xenopus tropicalis
• Alignment Length: 482
• Identity: 214/482 - (44%)
• Similarity: 313/482 - (64%)
• Gaps: 8/482 - (1%)

  Fly    22 LVLLLLELFLEGAESTASPADIENHLELGKEFLARGQLSDALTHYHAAVEGDANNYLTLFKRGTV 86
            |..::|:|.|:|. ..|:.|:||.|||:|::.||.|||::||:||||||:||.|||||.:||..|
 Frog    17 LFCVILDLQLDGL-LAANHAEIEGHLEMGRKLLAAGQLAEALSHYHAAVDGDPNNYLTYYKRAAV 80

  Fly    87 YLALGKTRFAVQDFSRVLELKPDFMAARIQRGVVHMKSGEYEQAIQDFDQVLQEEPNNGLVLEHY 151
            |||:||.|.|:.|.||.::|||||:|||:|||.:.:|.|:.::|.:||..|||..|.|.......
 Frog    81 YLAMGKFRSALPDLSRAIQLKPDFLAARLQRGNILLKQGDVQEAREDFLSVLQSSPTNEEAQNQL 145

  Fly   152 SRLAPAQEQWVLVQQLIQYSDHQNAIPMITQLLEISPWAVPFRQARSDAYIAINDPLLAIADLRQ 216
            .|:...:.......:..:..|:..||.::.:::|.|||....|:.|::.|:.:.:...|:.||:.
 Frog   146 ERVKEVESSMGGASEAYERRDYYGAIALLEKVIEFSPWDPSARELRAECYLLVGELSNAVQDLKP 210

  Fly   217 VNRLTQDSTEGHYKIAQLLYTIGHATNALKEIRECLKFDPEHKLCFPFYKKLRKVEKQLVNAEQA 281
            ..:|..|:.....|:::|.|::|....:|..:|||||.|.:.|.||..||:::|:.:||..||:.
 Frog   211 TTKLRNDNRAAFLKLSKLYYSMGEHGESLSHVRECLKLDQDDKDCFSHYKQVKKLSRQLDMAEEF 275

  Fly   282 REEKHFAECIAAGEAVLRNEPEETMIRYEGHKVLCTCYTGDEQFGKALQQCKEALDIMKDAQ--- 343
            .:|:.:.:.|...||.::.||..........:.:|.|.:..::..:|:..|.||.:  :|.|
 Frog   276 IQEQRYEDAIEKYEASIKTEPRVEEYSRRAKERICHCLSKSQRTEEAISVCTEAHE--RDPQNPL 338

  Fly   344 VYCDRADALLGTEMYDDAIHSFQAALDLEESNTRAKEGIQRAKKLQKQSERRDYYKILGVKRSAS 408
            :..|||:|.:..|.|:.|:..||.|.:|:..|...|||::||:||.|||::|||||||||||:|:
 Frog   339 ILRDRAEAYILNEEYEKAVEDFQQAKELDGENEEMKEGLERAQKLLKQSKKRDYYKILGVKRNAN 403

  Fly   409 KQEIVKAYRKAAQKWHPDNFR-DEEKKVAEKKFIDIAAAKEVLTDPEKRRQFDNGEDPLDPESNQ 472
            |||::|||||.||:||||||: :||||.|||||||||||||||||||.|::.|.||||||||:.|
 Frog   404 KQEVIKAYRKLAQQWHPDNFQSEEEKKEAEKKFIDIAAAKEVLTDPEMRQKVDAGEDPLDPENQQ 468

  Fly   473 RGGFHGEHPFGHFQHGS-PFQFKFHFN 498
            ..|.|...||.....|| .|||||:|:
 Frog   469 GSGHHQHWPFEFNPFGSGNFQFKFNFH 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
P58IPK	NP_649916.1	TPR repeat	43..71	CDD:276809	18/27 (67%)
		LapB	47..284	CDD:442196	94/236 (40%)
		TPR repeat	76..106	CDD:276809	17/29 (59%)
		TPR repeat	111..139	CDD:276809	12/27 (44%)
		TPR repeat	190..220	CDD:276809	6/29 (21%)
		LapB	196..>378	CDD:442196	54/184 (29%)
		TPR repeat	225..253	CDD:276809	8/27 (30%)
		TPR repeat	309..337	CDD:276809	6/27 (22%)
		TPR repeat	341..371	CDD:276809	12/32 (38%)
		TPR repeat	376..399	CDD:276809	13/22 (59%)
		PRK14278	395..>485	CDD:237654	66/90 (73%)
XB22063322	XP_002944642.2	LapB	30..333	CDD:442196	111/304 (37%)
		TPR repeat	37..65	CDD:276809	18/27 (67%)
		TPR repeat	70..100	CDD:276809	17/29 (59%)
		TPR repeat	105..133	CDD:276809	12/27 (44%)
		TPR repeat	139..179	CDD:276809	4/39 (10%)
		TPR repeat	184..214	CDD:276809	6/29 (21%)
		TPR repeat	219..247	CDD:276809	8/27 (30%)
		TPR repeat	269..293	CDD:276809	7/23 (30%)
		TPR repeat	298..332	CDD:276809	6/35 (17%)
		ACL4-like	320..>371	CDD:474029	17/52 (33%)
		TPR repeat	337..365	CDD:276809	10/27 (37%)
		TPR repeat	371..394	CDD:276809	13/22 (59%)
		PRK14278	390..>471	CDD:237654	62/80 (78%)