DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment P58IPK and CG3061

DIOPT Version :9

Sequence 1:	NP_649916.1	Gene:	P58IPK / 41161	FlyBaseID:	FBgn0037718	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	NP_650328.1	Gene:	CG3061 / 41707	FlyBaseID:	FBgn0038195	Length:	370	Species:	Drosophila melanogaster

Alignment Length:	274	Identity:	67/274 - (24%)
Similarity:	101/274 - (36%)	Gaps:	85/274 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   247 EIRECLKFDPEHKLCFPFYKKLRKVEKQLVNAEQAREEKHFAECIAAGEAVLRNEPEETMIRYEG 311
            |.:.|:.|..:....    .|:.|.||.|:.||:.....:..:.:|.    |::.|..     |.
  Fly     7 EAQRCIDFAVQALAA----GKIEKAEKFLLKAERLFPTDNAKKLLAQ----LKSTPSN-----ES 58

  Fly   312 HKVLCTCYTGDEQFGKALQQCKEALDIMKDA----QVYCDRADALLGTEMYDDAIHSFQAALDLE 372
            :....|....||                ||:    :|..|                |..:|.|..
  Fly    59 NGKSRTAGASDE----------------KDSGPRKRVNSD----------------SRSSAPDYT 91

  Fly   373 ESNTRAKEGIQRAKKLQKQSERRDYYKILGVKRSASKQEIVKAYRKAAQKWHPDNFRDEEKKVAE 437
            :....|...::..|         |||::|||.::|:..||.|||:|.|.:.|||.   .:...|.
  Fly    92 KDQLEAVRKVKTCK---------DYYEVLGVSKTATDSEIKKAYKKLALQLHPDK---NKAPGAV 144

  Fly   438 KKFIDIAAAKEVLTDPEKRRQFD--------NGEDPLDPESNQRGGFHGEHPFGHFQHG--SPFQ 492
            :.|..:..|..||||.|||:.:|        ||      ..|..||.||...:.:.::|  ..||
  Fly   145 EAFKALGNAAGVLTDAEKRKNYDLYGINESHNG------HGNNGGGHHGHGQYYNNEYGYSRGFQ 203

  Fly   493 --------FKFHFN 498
                    |...||
  Fly   204 ADISAEELFNMFFN 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
P58IPK	NP_649916.1	TPR_11	42..108	CDD:290150
		TPR repeat	43..71	CDD:276809
		TPR repeat	76..106	CDD:276809
		TPR_11	78..142	CDD:290150
		TPR repeat	111..139	CDD:276809
		TPR_1	113..144	CDD:278916
		TPR_19	167..234	CDD:291240
		TPR repeat	190..220	CDD:276809
		TPR repeat	225..253	CDD:276809	2/5 (40%)
		TPR repeat	309..337	CDD:276809	4/27 (15%)
		TPR_11	312..373	CDD:290150	10/64 (16%)
		TPR repeat	341..371	CDD:276809	5/33 (15%)
		TPR repeat	376..399	CDD:276809	4/22 (18%)
		DnaJ	395..>485	CDD:223560	35/97 (36%)
		DnaJ	396..460	CDD:278647	27/63 (43%)
CG3061	NP_650328.1	DnaJ	105..>224	CDD:223560	42/131 (32%)
		DnaJ	106..167	CDD:278647	27/63 (43%)
		DUF1977	269..366	CDD:286411
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910