DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8301 and Zfp551

DIOPT Version :9

Sequence 1:	NP_649915.1	Gene:	CG8301 / 41160	FlyBaseID:	FBgn0037717	Length:	607	Species:	Drosophila melanogaster
Sequence 2:	XP_003748789.1	Gene:	Zfp551 / 682964	RGDID:	1592780	Length:	721	Species:	Rattus norvegicus

Alignment Length:	438	Identity:	122/438 - (27%)
Similarity:	184/438 - (42%)	Gaps:	55/438 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   186 SYACKFCLRPQENYQLQQLLLEH------------INASH---DPEQPYNCPECEARFQDAASRT 235
            :::|.:.|...::....|...||            :|...   ..|:|:.|.||...|...:...
  Rat   314 AFSCNYKLAQHQDSHPGQRTYEHTQNEKSFRKKCRLNTQDRICPQERPFKCTECGKAFIYKSELI 378

  Fly   236 VHLKSSHVEKQHACGVCGKKYGDRHNLRHHVEKYHSETDFECALCEKRFYTRKSLNYHMKWHNPD 300
            .|.:.......:.|..|.|.:..:.||..|...:..|..::|..|.|.|....||..|.:.|..:
  Rat   379 YHQRHHSGRVHYECKECRKSFTYKSNLTEHQRIHTGERPYQCEQCGKSFRQNSSLFRHHRIHTGE 443

  Fly   301 RQFKCRHSGCERLFISQRHLMCHEATHSGTSSRKSEHCGFCGKTFIHLKTLRWHIYRQHGGEKPY 365
            |.::|..  |.:.|....:|:.|...|||   .....||.|||.|.....|..| .|.|.|||||
  Rat   444 RPYECYE--CGKSFRQIFNLIRHRRVHSG---EMPHQCGDCGKAFSCKAELTQH-ERIHSGEKPY 502

  Fly   366 KCANCTEVFASYAEKRIHMLERHRENLTAIERSECMLCRQPFSSEPDLIHHMSAEHLQRPGAPII 430
            :|:.|.:.|..::.     |.|||...|.....:|..|.:.||.:..||.|......:||
  Rat   503 ECSECGKYFRQFSN-----LIRHRRVHTGDRPYKCSECEKSFSRKFILIQHQRVHTGERP----- 557

  Fly   431 ANNKRVLQQKRERQYSGLFQCGSCSQRFNMKSALERHAAVHSEKDRPHACPHCSKRFKRAQDMKW 495
                              ::||.|...|..||.|.:|..:|: ..||:.|..|.|.|::...:..
  Rat   558 ------------------YKCGECGTSFTRKSDLIQHQRIHT-GTRPYECEECGKAFRQCSSLIQ 603

  Fly   496 HIKTHEKEKPNVCDVCGKAFALKYVLTQHRLSHEVLEKNFKCNVCGRAYLFEKSLRLHQRTHTGK 560
            |.:.|..|||..|..|||||:....|.||:..| ..|:.::|:.||:::....||..|||:|:|:
  Rat   604 HRRVHTGEKPYECIECGKAFSQSASLIQHQRLH-TGERPYECSECGKSFSQSASLIQHQRSHSGE 667

  Fly   561 TYYKCDLCQERFVTHIKLKTHMQKAHAASQP---HSADQPLDDLINIV 605
            ..|:|..|.:.|.....|..| |:.|...:|   |..::......|:|
  Rat   668 KPYECSECGKPFTHKSDLIQH-QRVHTGERPYECHGCEKSFSRRSNLV 714

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8301	NP_649915.1	zf-AD	3..87	CDD:285071
		COG5048	198..>508	CDD:227381	87/324 (27%)
		C2H2 Zn finger	221..241	CDD:275368	5/19 (26%)
		C2H2 Zn finger	249..269	CDD:275368	6/19 (32%)
		C2H2 Zn finger	277..297	CDD:275368	7/19 (37%)
		C2H2 Zn finger	305..327	CDD:275368	5/21 (24%)
		C2H2 Zn finger	338..359	CDD:275368	9/20 (45%)
		C2H2 Zn finger	367..384	CDD:275368	3/16 (19%)
		C2H2 Zn finger	400..420	CDD:275368	7/19 (37%)
		C2H2 Zn finger	451..471	CDD:275368	8/19 (42%)
		C2H2 Zn finger	480..500	CDD:275368	5/19 (26%)
		C2H2 Zn finger	508..528	CDD:275368	9/19 (47%)
		C2H2 Zn finger	537..557	CDD:275368	8/19 (42%)
		C2H2 Zn finger	565..582	CDD:275368	4/16 (25%)
Zfp551	XP_003748789.1	KRAB	70..>113	CDD:214630
		KRAB	70..109	CDD:279668
		C2H2 Zn finger	308..328	CDD:275368	2/13 (15%)
		C2H2 Zn finger	364..384	CDD:275368	5/19 (26%)
		COG5048	390..720	CDD:227381	109/362 (30%)
		zf-C2H2	390..412	CDD:278523	6/21 (29%)
		C2H2 Zn finger	392..412	CDD:275368	6/19 (32%)
		zf-H2C2_2	404..429	CDD:290200	8/24 (33%)
		C2H2 Zn finger	420..440	CDD:275368	7/19 (37%)
		zf-H2C2_2	432..457	CDD:290200	8/26 (31%)
		C2H2 Zn finger	448..468	CDD:275368	5/21 (24%)
		zf-H2C2_2	460..485	CDD:290200	11/27 (41%)
		C2H2 Zn finger	476..496	CDD:275368	9/20 (45%)
		zf-H2C2_2	488..513	CDD:290200	12/25 (48%)
		C2H2 Zn finger	504..524	CDD:275368	7/24 (29%)
		zf-H2C2_2	516..541	CDD:290200	8/29 (28%)
		C2H2 Zn finger	532..552	CDD:275368	7/19 (37%)
		zf-H2C2_2	545..569	CDD:290200	9/46 (20%)
		C2H2 Zn finger	560..580	CDD:275368	8/19 (42%)
		zf-H2C2_2	572..597	CDD:290200	9/25 (36%)
		C2H2 Zn finger	588..608	CDD:275368	5/19 (26%)
		zf-H2C2_2	600..625	CDD:290200	11/24 (46%)
		C2H2 Zn finger	616..636	CDD:275368	9/19 (47%)
		zf-H2C2_2	628..653	CDD:290200	8/25 (32%)
		C2H2 Zn finger	644..664	CDD:275368	8/19 (42%)
		zf-H2C2_2	656..681	CDD:290200	11/24 (46%)
		C2H2 Zn finger	672..692	CDD:275368	6/20 (30%)
		zf-H2C2_2	684..709	CDD:290200	6/25 (24%)
		zf-C2H2	698..720	CDD:278523	3/17 (18%)
		C2H2 Zn finger	700..720	CDD:275368	3/15 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24377
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100