DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8301 and Zfp583

DIOPT Version :9

Sequence 1:NP_649915.1 Gene:CG8301 / 41160 FlyBaseID:FBgn0037717 Length:607 Species:Drosophila melanogaster
Sequence 2:NP_001128081.2 Gene:Zfp583 / 499068 RGDID:1562044 Length:568 Species:Rattus norvegicus


Alignment Length:536 Identity:138/536 - (25%)
Similarity:229/536 - (42%) Gaps:75/536 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    68 TKFCS-INAFRLACQEAQLKLSHIYDKIDASSLEDDEIGQEDLEPAEEHQETETTKPTTTVSAET 131
            |:|.| .:.::.:.:...:..||...:.|.|:|:::...::..:.....||..:::...|.....
  Rat    86 TEFISKQDIYKASAKVLTMGRSHFSSRFDCSNLKENHESKDWFKNRLGGQEVCSSQSLITHKEVP 150

  Fly   132 QPNNTASDP-IEIFVDAVDIDEAEEEEEEEEQQQQYDEEVEEPITDESAPPQLTISYACKFCLRP 195
            :..::..:| .:.|.....:|..:....:|.             .|:|.|              .
  Rat   151 ENQSSVCNPSCQAFHQDAILDTPQSFSTKER-------------IDQSEP--------------Q 188

  Fly   196 QENYQLQQLLLEHINASHDPEQPYNCPECEARFQDAASRTVHLKSSHVEKQHACGVCGKKYGDRH 260
            :.:|:.:.:.::| ...|..::...|.|||..|..::|.|:|.:....||.:||..|||.:....
  Rat   189 KRSYRKKPIEMKH-KKVHVEKKILKCTECEKVFNQSSSLTLHQRIHTGEKPYACVECGKAFSQSA 252

  Fly   261 NLRHHVEKYHSETDFECALCEKRFYTRKSLNYHMKWHNPDRQFKCRHSGCERLFISQRHLMCHEA 325
            ||..|...:..|..:||..|.|.|.....|..|.:.|..::.::|:.  |::.|....||..|:.
  Rat   253 NLAQHKRIHTGEKPYECKECRKAFSQNAHLAQHQRVHTGEKPYQCKE--CKKAFSQIAHLTQHQR 315

  Fly   326 THSGTSSRKSEHCGFCGKTFIHLKTLRWHIYRQHGGEKPYKCANCTEVFAS----YAEKRIHMLE 386
            .|:|   .:...|..|||.|.:...|..| .|.|.|||||.|..|.:.|:.    ...:|||..|
  Rat   316 IHTG---ERPFECIECGKAFSNGSFLAQH-QRIHTGEKPYVCHVCGKAFSHRGYLIVHQRIHTGE 376

  Fly   387 RHRENLTAIERSECMLCRQPFSSEPDLIHHMSAEHLQRPGAPIIANNKRVLQQKRERQYSGLFQC 451
            |         ..||..||:.||....|..|......::|                       ::|
  Rat   377 R---------PYECKECRKSFSQYAHLSQHQRVHTGEKP-----------------------YEC 409

  Fly   452 GSCSQRFNMKSALERHAAVHSEKDRPHACPHCSKRFKRAQDMKWHIKTHEKEKPNVCDVCGKAFA 516
            ..|.:.|:..:.|::|..||: .::|:.|..|.|.|..:..:..|.::|..|||.:|..|.|.|:
  Rat   410 KVCRKAFSQIAYLDQHQRVHT-GEKPYECAECRKAFSNSSSLAQHQRSHTGEKPYICKECRKTFS 473

  Fly   517 LKYVLTQHRLSHEVLEKNFKCNVCGRAYLFEKSLRLHQRTHTGKTYYKCDLCQERFVTHIKLKTH 581
            ....|.||:..| ..||.::||:||:|:.:..||.||||.|||:..|:|..|::.|.....| .|
  Rat   474 QNAGLAQHQRIH-TGEKPYECNICGKAFSYSGSLTLHQRIHTGERPYECKDCRKSFRQRAHL-AH 536

  Fly   582 MQKAHAASQPHSADQP 597
            .:|.|......|...|
  Rat   537 HEKVHTMESLLSLSSP 552

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8301NP_649915.1 zf-AD 3..87 CDD:285071 3/19 (16%)
COG5048 198..>508 CDD:227381 86/313 (27%)
C2H2 Zn finger 221..241 CDD:275368 8/19 (42%)
C2H2 Zn finger 249..269 CDD:275368 7/19 (37%)
C2H2 Zn finger 277..297 CDD:275368 6/19 (32%)
C2H2 Zn finger 305..327 CDD:275368 6/21 (29%)
C2H2 Zn finger 338..359 CDD:275368 8/20 (40%)
C2H2 Zn finger 367..384 CDD:275368 5/20 (25%)
C2H2 Zn finger 400..420 CDD:275368 7/19 (37%)
C2H2 Zn finger 451..471 CDD:275368 5/19 (26%)
C2H2 Zn finger 480..500 CDD:275368 5/19 (26%)
C2H2 Zn finger 508..528 CDD:275368 7/19 (37%)
C2H2 Zn finger 537..557 CDD:275368 11/19 (58%)
C2H2 Zn finger 565..582 CDD:275368 4/16 (25%)
Zfp583NP_001128081.2 KRAB 6..66 CDD:214630
COG5048 212..541 CDD:227381 114/369 (31%)
C2H2 Zn finger 213..233 CDD:275368 8/19 (42%)
C2H2 Zn finger 241..261 CDD:275368 7/19 (37%)
C2H2 Zn finger 269..289 CDD:275368 6/19 (32%)
C2H2 Zn finger 297..317 CDD:275368 6/21 (29%)
C2H2 Zn finger 325..345 CDD:275368 8/20 (40%)
C2H2 Zn finger 353..373 CDD:275368 4/19 (21%)
C2H2 Zn finger 381..401 CDD:275368 7/19 (37%)
C2H2 Zn finger 409..429 CDD:275368 5/19 (26%)
C2H2 Zn finger 437..457 CDD:275368 5/19 (26%)
C2H2 Zn finger 465..485 CDD:275368 7/19 (37%)
C2H2 Zn finger 493..513 CDD:275368 11/19 (58%)
C2H2 Zn finger 521..541 CDD:275368 6/20 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24377
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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