DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8301 and AgaP_AGAP011409

DIOPT Version :9

Sequence 1:	NP_649915.1	Gene:	CG8301 / 41160	FlyBaseID:	FBgn0037717	Length:	607	Species:	Drosophila melanogaster
Sequence 2:	XP_001238000.1	Gene:	AgaP_AGAP011409 / 4577549	VectorBaseID:	AGAP011409	Length:	298	Species:	Anopheles gambiae

Alignment Length:	361	Identity:	81/361 - (22%)
Similarity:	129/361 - (35%)	Gaps:	97/361 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   177 ESAPPQLTISYACKFCLRPQENYQLQQLLLEHINASHDPEQPYNCPECE-ARFQDAASRTVHLKS 240
            |:||.| |:| .|:|||  .|:.:....:||.||.:...|...:|...: |...:.||..|.|:.
Mosquito     2 ENAPQQ-TVS-VCRFCL--CEDAEKLIPVLETINPTLTIEDVEHCTGLQIATDDELASCAVCLEC 62

  Fly   241 SHVEKQHACGVCGKKYGDRHNLRHHVEKYH-------SETDFECA--LCEKRFYTRKSLNYHMK- 295
            :...|      |...:  |....::...|.       ::||..||  |.|:.......:...::
Mosquito    63 TDALK------CSADF--RRTCMYNDSLYKEMRLTRLTKTDDTCAFDLVEEYLENPDEIAGELQA 119

  Fly   296 -WHNPDRQFKCRHSGCERLFISQRHLMCHEATHSGTSSRKSEHCGFCGKTFIHLKTLRWHIYRQH 359
             ...||::.|..:...|.::                           |:.   ::.|..|
Mosquito   120 VVLKPDQEIKLEYVDEEEIY---------------------------GRA---IRVLSTH----- 149

  Fly   360 GGEKPYKCANCTEVFASYAEKRIHMLERHRENLTAIERSECMLCRQPFSSEPDLIHHMSAEHLQR 424
             ||..|.        |:|.|..    |.:.||..|...:       |.::.|.......|.|
Mosquito   150 -GEVGYS--------ANYIEPG----ETNPENDEAYYAT-------PPANIPKYQQIKKATH--- 191

  Fly   425 PGAPIIANNKRVLQQKRERQYSGLFQCGSCSQRFNMKSALERHAAVHSEKDRPHACPHCSKRFKR 489
                   .:|....||.:|:.|....|||      :...|:||...|::... |.||:|..:..:
Mosquito   192 -------TSKERRAQKMKRKKSLCDMCGS------IVINLQRHTLNHTQAVM-HGCPYCPIKMTQ 242

  Fly   490 AQDMKWHIKT-HEKEKPNVCDVCGKAFALKYVLTQH 524
            ..:|..||:| |.|.....|.:|||.|......:.|
Mosquito   243 KTNMVQHIETVHFKTIGKTCCICGKGFVHHKTYSYH 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8301	NP_649915.1	zf-AD	3..87	CDD:285071
		COG5048	198..>508	CDD:227381	64/322 (20%)
		C2H2 Zn finger	221..241	CDD:275368	6/20 (30%)
		C2H2 Zn finger	249..269	CDD:275368	2/19 (11%)
		C2H2 Zn finger	277..297	CDD:275368	4/23 (17%)
		C2H2 Zn finger	305..327	CDD:275368	1/21 (5%)
		C2H2 Zn finger	338..359	CDD:275368	3/20 (15%)
		C2H2 Zn finger	367..384	CDD:275368	3/16 (19%)
		C2H2 Zn finger	400..420	CDD:275368	2/19 (11%)
		C2H2 Zn finger	451..471	CDD:275368	6/19 (32%)
		C2H2 Zn finger	480..500	CDD:275368	7/20 (35%)
		C2H2 Zn finger	508..528	CDD:275368	6/17 (35%)
		C2H2 Zn finger	537..557	CDD:275368
		C2H2 Zn finger	565..582	CDD:275368
AgaP_AGAP011409	XP_001238000.1	zf-AD	11..85	CDD:214871	20/83 (24%)
		C2H2 Zn finger	233..254	CDD:275368	7/20 (35%)
		C2H2 Zn finger	262..279	CDD:275368	6/17 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000098
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000