DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8301 and AgaP_AGAP012704

DIOPT Version :9

Sequence 1:	NP_649915.1	Gene:	CG8301 / 41160	FlyBaseID:	FBgn0037717	Length:	607	Species:	Drosophila melanogaster
Sequence 2:	XP_001230479.2	Gene:	AgaP_AGAP012704 / 4397589	VectorBaseID:	AGAP012704	Length:	285	Species:	Anopheles gambiae

Alignment Length:	209	Identity:	48/209 - (22%)
Similarity:	79/209 - (37%)	Gaps:	24/209 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   410 EPDLIHHMSAEHLQRPGAPIIANNKRVLQQK------------RERQYSGL------FQCGSCSQ 456
            :.|...|.|.....|.|...:...||..:::            ||.:.|..      ..|..|.
Mosquito    81 DDDFTWHESETDPARDGKQKLVRKKRPNRKRAGAEQIKRRDPAREAKSSSTGGRSTRVLCSICG- 144

  Fly   457 RFNMKSALERHAAVHSEKDR-PHACPHCSKRFKRAQDMKWHIKT-HEKEKPNVCDVCGKAFALKY 519
              ...|.|..|...|..|.. ..:||||..:....:::..||.| |.|.....|::|||.|....
Mosquito   145 --TFVSNLNFHQNYHHAKTSIKLSCPHCPAKITHQKNLTRHINTVHLKIVEKTCEICGKEFTTNN 207

  Fly   520 VLTQHRLSHEVLEKNFKCNVCGRAYLFEKSLRLHQRTHTGKTYYKCDLCQERFVTHIKLKTHMQK 584
            ....|.:...:....:.|..|.:.:....:.:.|:.||:| ..:||.||::.:.....|..||:|
Mosquito   208 SYVSHMVRRYIARWPYACTQCPKRFKSRFARKTHELTHSG-VLFKCTLCEKSYRYKSLLSMHMRK 271

  Fly   585 AHAASQPHSADQPL 598
            .|.....|:.::.:
Mosquito   272 MHPEENTHNEEESI 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8301	NP_649915.1	zf-AD	3..87	CDD:285071
		COG5048	198..>508	CDD:227381	26/117 (22%)
		C2H2 Zn finger	221..241	CDD:275368
		C2H2 Zn finger	249..269	CDD:275368
		C2H2 Zn finger	277..297	CDD:275368
		C2H2 Zn finger	305..327	CDD:275368
		C2H2 Zn finger	338..359	CDD:275368
		C2H2 Zn finger	367..384	CDD:275368
		C2H2 Zn finger	400..420	CDD:275368	3/9 (33%)
		C2H2 Zn finger	451..471	CDD:275368	5/19 (26%)
		C2H2 Zn finger	480..500	CDD:275368	7/20 (35%)
		C2H2 Zn finger	508..528	CDD:275368	6/19 (32%)
		C2H2 Zn finger	537..557	CDD:275368	3/19 (16%)
		C2H2 Zn finger	565..582	CDD:275368	4/16 (25%)
AgaP_AGAP012704	XP_001230479.2	C2H2 Zn finger	167..188	CDD:275368	7/20 (35%)
		C2H2 Zn finger	196..217	CDD:275368	6/20 (30%)
		C2H2 Zn finger	225..245	CDD:275368	3/19 (16%)
		C2H2 Zn finger	252..270	CDD:275368	5/17 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000098
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000