DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8301 and pad

DIOPT Version :9

Sequence 1:	NP_649915.1	Gene:	CG8301 / 41160	FlyBaseID:	FBgn0037717	Length:	607	Species:	Drosophila melanogaster
Sequence 2:	NP_650534.2	Gene:	pad / 41981	FlyBaseID:	FBgn0038418	Length:	924	Species:	Drosophila melanogaster

Alignment Length:	329	Identity:	78/329 - (23%)
Similarity:	119/329 - (36%)	Gaps:	94/329 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   125 TTVSAETQPNNT----ASDPIEIFVDAVDIDEAEEEEEEEEQQQQYDEEVEEPITDESAPPQLTI 185
            |...|:::|:.|    ||.||.:.|                           |...::.||.|..
  Fly   618 TAPKAQSKPSTTSPTPASQPIPVSV---------------------------PALSQAQPPPLAA 655

  Fly   186 SYACKFCLRPQENYQLQQLLLEHINASHDPEQPYNCPECEARFQDAASRTVHLKSSHVEKQHACG 250
            .:. |...:|.||   |....:.:.|:..|:|....|:.|.:
  Fly   656 QHK-KIVRKPPEN---QDTSGQKVKAARPPQQILPSPQQEGQ----------------------- 693

  Fly   251 VCGKKYGDRHNLRHHVEKYHSETDFECALCEKRFYTRKSLNYHMKWHNPDRQFKCRHSGCERLFI 315
                      |..|...:..:.:...|..|::.|..::.|..|:|.|...|.|||...||::.|.
  Fly   694 ----------NATHSGSEAPTTSGLICPTCKREFKKKEHLTQHVKLHAGLRPFKCSEEGCDKTFS 748

  Fly   316 SQRHLMCHEATHSGTSSRKSEHCGFCGKTFIHLKTLRWH--IYRQHGGEKPYKCANCTEVFASYA 378
            .:.||..|..:|||   :|...|..|.|.|.....|..|  |:.|...|..|.|..|.:.||:
  Fly   749 RKEHLSRHLVSHSG---QKMYTCEVCKKPFSRKDNLNKHRRIHTQTSTETLYCCDVCNKNFAT-- 808

  Fly   379 EKRIHMLERHRENLTAIERSECMLCRQPFSSEPDLIHHMSA----EHLQRPGAPIIANNKRVLQQ 439
              ::| .|:|||....|         :|.|:.|......:|    .|::..|.   ..||.|.:.
  Fly   809 --KLH-YEKHREMHKKI---------RPESAAPGATASPAAAPALTHVRSNGQ---VPNKAVFEI 858

  Fly   440 KRER 443
            |:||
  Fly   859 KQER 862

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8301	NP_649915.1	zf-AD	3..87	CDD:285071
		COG5048	198..>508	CDD:227381	62/252 (25%)
		C2H2 Zn finger	221..241	CDD:275368	2/19 (11%)
		C2H2 Zn finger	249..269	CDD:275368	2/19 (11%)
		C2H2 Zn finger	277..297	CDD:275368	6/19 (32%)
		C2H2 Zn finger	305..327	CDD:275368	7/21 (33%)
		C2H2 Zn finger	338..359	CDD:275368	7/22 (32%)
		C2H2 Zn finger	367..384	CDD:275368	4/16 (25%)
		C2H2 Zn finger	400..420	CDD:275368	4/23 (17%)
		C2H2 Zn finger	451..471	CDD:275368
		C2H2 Zn finger	480..500	CDD:275368
		C2H2 Zn finger	508..528	CDD:275368
		C2H2 Zn finger	537..557	CDD:275368
		C2H2 Zn finger	565..582	CDD:275368
pad	NP_650534.2	zf-AD	16..87	CDD:214871
		C2H2 Zn finger	710..730	CDD:275368	6/19 (32%)
		zf-C2H2	736..760	CDD:278523	9/23 (39%)
		C2H2 Zn finger	738..760	CDD:275368	7/21 (33%)
		zf-H2C2_2	752..777	CDD:290200	11/27 (41%)
		zf-C2H2	766..788	CDD:278523	6/21 (29%)
		C2H2 Zn finger	768..788	CDD:275368	6/19 (32%)
		zf-H2C2_2	780..808	CDD:290200	9/27 (33%)
		C2H2 Zn finger	799..819	CDD:275368	9/24 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24377
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100