DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8301 and Meics

DIOPT Version :9

Sequence 1:NP_649915.1 Gene:CG8301 / 41160 FlyBaseID:FBgn0037717 Length:607 Species:Drosophila melanogaster
Sequence 2:NP_524062.1 Gene:Meics / 39539 FlyBaseID:FBgn0025874 Length:583 Species:Drosophila melanogaster


Alignment Length:658 Identity:165/658 - (25%)
Similarity:251/658 - (38%) Gaps:178/658 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 ETCRTCAISMFVCDFENGSNNSHFLDL-----HHPNCWP------SEMAQIRLQFANWNLKISPN 55
            :.||.||           .::|..:||     ..|..|.      .|:.:::            .
  Fly    19 KNCRACA-----------EHSSILVDLFSKEISDPPIWEMLNSILPEICRVK------------R 60

  Fly    56 DGLPQKICSDCFTKFCSINAFRLACQEAQLKLSHI--YDKIDASSLEDDEIGQEDLEP------- 111
            |.:|||||..|.....:...||..|:::....|.:  .||.: |:|......:..:.|       
  Fly    61 DEMPQKICPTCLVAAQNAFHFRHKCEQSFQFFSQLLQLDKSN-SNLSRSHCRRGTMNPLIPFEIV 124

  Fly   112 -AEEHQETETTK-------PTTTVSAETQ---PNNTASDPI-EIF-VDAVDIDEAEEEEEEEEQQ 163
             .|:..:|..||       ..|.:...|.   .|...|:|: |:| :...||...:|...:|..:
  Fly   125 GCEDPLDTNVTKLDANRPDVKTDIDEPTDGKATNGQESEPLQEVFEITMNDIKTEDEVSIQETFE 189

  Fly   164 QQYDEEVEEPITDESAPPQLTISYACKFCLRPQENYQLQQLLLEHINASHDPEQPY--------- 219
            ..:|||.:...||                   .|.....|..   :.::.|.::|:         
  Fly   190 DAFDEENDNNNTD-------------------SEREDSDQWT---VGSTEDQDEPWIPGGGGRQT 232

  Fly   220 --------NCPECEARF--QDAASRTV--HLKSSHVEKQHACGVCGKKYGDRHNLRHHVEKYHSE 272
                    .|.||...:  |.|.:|.|  |.:....:|.|.|..||:.:.....|..|..::..|
  Fly   233 VGGNNQSLLCTECGVSYSTQKALARHVAKHKEQGDTQKPHLCDFCGRGFRTNAQLTTHRRRHTGE 297

  Fly   273 TDFECALCEKRFYTRKSLNYHMKWHNPDRQFKCRHSGCERLFISQRHLMCHEATHSGTSSRKSEH 337
            ..|:|.||.|.:....:|..||..|:.::..||..                              
  Fly   298 RPFKCPLCPKAYTHGPTLKSHMHTHDEEKGHKCPQ------------------------------ 332

  Fly   338 CGFCGKTFIHLKTLRWHIYRQHGGEKPYKCANCTEVFASYAEKRIHMLERHRENLTAIERS-ECM 401
               |.|||.....||.||.| |.||:||||.:|.:.||..:..::|. ..|:|     ||. :|.
  Fly   333 ---CDKTFYTRGNLRAHIQR-HTGERPYKCPDCPQTFAKNSGLKLHS-RLHKE-----ERPFKCE 387

  Fly   402 LCRQPFSSEPDLIHHMSAEHLQRPGAPIIANNKRVLQQKRERQYSGLFQCGSCSQRFNMKSALER 466
            ||.:.|.....||.|:...:                   .:||    |:|..|.:.|..||.:.:
  Fly   388 LCGKGFVQNQHLITHLRVHN-------------------GDRQ----FKCPDCDKSFFEKSNMMK 429

  Fly   467 HAAVHSEKDRPHACPHCSKRFKRAQDMKWHIKTHEKEKPNVCDVCGKAFALKYVLTQHRLSH-EV 530
            |...|| ..:|..|..|.:.|.....:|.|::.|..|||..||.|||.|:....|.:|.|.| :.
  Fly   430 HQRTHS-GIKPFKCEECGQAFSHNHHLKSHLRIHTGEKPYKCDQCGKGFSANQSLMKHTLWHVDN 493

  Fly   531 LEKNFKCNVCGRAYLFEKSLRLHQRTHTG----KTYYKCDLCQERFVTHIKLKTHMQKAHAAS-- 589
            .::.|||:.|.:||..::|||.|::||..    ||.::|..|..||.    ||..:.| |..|  
  Fly   494 NDRPFKCSQCPKAYDTQQSLRGHEKTHKNPDEPKTLHQCPHCDVRFA----LKKTLDK-HITSHK 553

  Fly   590 -QPHSADQ 596
             :||...|
  Fly   554 IRPHPCPQ 561

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8301NP_649915.1 zf-AD 3..87 CDD:285071 20/94 (21%)
COG5048 198..>508 CDD:227381 82/331 (25%)
C2H2 Zn finger 221..241 CDD:275368 8/23 (35%)
C2H2 Zn finger 249..269 CDD:275368 5/19 (26%)
C2H2 Zn finger 277..297 CDD:275368 7/19 (37%)
C2H2 Zn finger 305..327 CDD:275368 1/21 (5%)
C2H2 Zn finger 338..359 CDD:275368 9/20 (45%)
C2H2 Zn finger 367..384 CDD:275368 4/16 (25%)
C2H2 Zn finger 400..420 CDD:275368 7/19 (37%)
C2H2 Zn finger 451..471 CDD:275368 6/19 (32%)
C2H2 Zn finger 480..500 CDD:275368 5/19 (26%)
C2H2 Zn finger 508..528 CDD:275368 9/19 (47%)
C2H2 Zn finger 537..557 CDD:275368 8/19 (42%)
C2H2 Zn finger 565..582 CDD:275368 6/16 (38%)
MeicsNP_524062.1 zf-AD 21..95 CDD:285071 21/96 (22%)
C2H2 Zn finger 242..262 CDD:275368 7/19 (37%)
C2H2 Zn finger 274..294 CDD:275368 5/19 (26%)
zf-H2C2_2 287..311 CDD:290200 8/23 (35%)
C2H2 Zn finger 302..322 CDD:275368 7/19 (37%)
C2H2 Zn finger 330..350 CDD:275368 10/53 (19%)
zf-H2C2_2 342..366 CDD:290200 13/24 (54%)
C2H2 Zn finger 358..378 CDD:275368 5/20 (25%)
C2H2 Zn finger 386..406 CDD:275368 7/19 (37%)
COG5048 <395..583 CDD:227381 60/196 (31%)
zf-C2H2 412..434 CDD:278523 7/21 (33%)
C2H2 Zn finger 414..434 CDD:275368 6/19 (32%)
zf-H2C2_2 426..451 CDD:290200 7/25 (28%)
C2H2 Zn finger 442..462 CDD:275368 5/19 (26%)
zf-H2C2_2 454..478 CDD:290200 11/23 (48%)
C2H2 Zn finger 470..486 CDD:275368 7/15 (47%)
C2H2 Zn finger 500..520 CDD:275368 8/19 (42%)
C2H2 Zn finger 532..552 CDD:275370 8/24 (33%)
C2H2 Zn finger 559..579 CDD:275370 1/3 (33%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 91 1.000 Inparanoid score I2264
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24377
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
22.150

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