DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8301 and MTF-1

DIOPT Version :9

Sequence 1:NP_649915.1 Gene:CG8301 / 41160 FlyBaseID:FBgn0037717 Length:607 Species:Drosophila melanogaster
Sequence 2:NP_001097560.1 Gene:MTF-1 / 39089 FlyBaseID:FBgn0040305 Length:1006 Species:Drosophila melanogaster


Alignment Length:536 Identity:118/536 - (22%)
Similarity:189/536 - (35%) Gaps:174/536 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    74 NAFRLACQEAQLKLS-------HIYDKIDAS--------SLED--------DEIGQEDLEPAEEH 115
            |||.||.|...|.::       |..:.:.:|        ||.|        |:| ...||...|:
  Fly   151 NAFSLADQLTPLPITVIPITYHHTTENLSSSHSEVPLIASLSDITAQVFNLDDI-CFTLEYQFEN 214

  Fly   116 QETETTKPTTTVSAE--TQPNNTASDPIEI---------------------------FVDAVDID 151
            |.....:|.|.||..  :.||..|:.||..                           :||..|.:
  Fly   215 QRLVQVQPPTVVSLSMVSSPNEAANPPINCDNDQGTGNSISRDSTSNSPAYFTIETSYVDEYDPN 279

  Fly   152 EAEEEE---------------EEEEQQQQYDEEVEEPITDESAPPQLTISYACKF--CLRPQENY 199
            |.:|:|               :|||.::|.:.:....:..||:...|: .|.|.:  |.|   :|
  Fly   280 EPDEDEQLAHCIQPGVLHQDVDEEEVERQDENDQLMALAYESSDEALS-RYRCNYENCYR---SY 340

  Fly   200 QLQQLLLEHINASHDPEQPYNCPE--CEARFQDAASRTVHLKSSHVEKQHACGV--CGKKYGDRH 260
            .....|..|:. :|..:..:.|||  |...|..:.|..:|::.....|.:.|.|  |.|.:..|:
  Fly   341 STIGNLRTHLK-THTGDYSFKCPEDGCHKAFLTSYSLKIHVRVHTKVKPYECEVSGCDKAFNTRY 404

  Fly   261 NLRHHVEKYHSETDFECALCEKRFYTRKSLNYHMKWHNPDRQFKCRHSGCERLFISQRHLMCHEA 325
            .|..|:..::.|| |.|.||:|.|.|...|..||:.|..:|.:||....|.:.|.:..||..|..
  Fly   405 RLHAHLRLHNGET-FNCELCQKCFTTLSDLKKHMRTHTQERPYKCPEDDCGKAFTASHHLKTHRR 468

  Fly   326 THSGTSSRKSEHCGFCGKTFIHLKTLRWHIYRQHGGEKPYKCA--NCTEVFASYAEKRIHMLERH 388
            ||:                                |||||.|.  :|.:.|::     .|.|:.|
  Fly   469 THT--------------------------------GEKPYPCQEDSCQKSFST-----SHSLKSH 496

  Fly   389 RENLTAIERSECMLCRQPFSSEPDLIHHMSAEHLQRPGAPIIANNKRVLQQKRERQYSGLFQCGS 453
            ::.                        |.  ..||..|     ..||.|:.::.:       |..
  Fly   497 KKT------------------------HQ--RQLQNKG-----RKKRPLKTQQTK-------CSD 523

  Fly   454 CSQRFNMKSALERHAAVHSEKDRPHAC-----PHCSK----------RFKRAQDMKWHIKTHEKE 503
            ..|:...:...|....:  ::|:|...     .|||:          :....||...::...:..
  Fly   524 QEQKDPQQEEQEEEEFI--KEDQPEMTLLNPGSHCSETTSTDSGVVLQTLTPQDHLSNVFILQGN 586

  Fly   504 KPNVCDVCGKAFALKY 519
            :|.:.....:|:.|.|
  Fly   587 EPLILPETSQAYQLSY 602

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8301NP_649915.1 zf-AD 3..87 CDD:285071 7/12 (58%)
COG5048 198..>508 CDD:227381 71/330 (22%)
C2H2 Zn finger 221..241 CDD:275368 7/21 (33%)
C2H2 Zn finger 249..269 CDD:275368 7/21 (33%)
C2H2 Zn finger 277..297 CDD:275368 9/19 (47%)
C2H2 Zn finger 305..327 CDD:275368 6/21 (29%)
C2H2 Zn finger 338..359 CDD:275368 0/20 (0%)
C2H2 Zn finger 367..384 CDD:275368 3/18 (17%)
C2H2 Zn finger 400..420 CDD:275368 1/19 (5%)
C2H2 Zn finger 451..471 CDD:275368 3/19 (16%)
C2H2 Zn finger 480..500 CDD:275368 5/34 (15%)
C2H2 Zn finger 508..528 CDD:275368 3/12 (25%)
C2H2 Zn finger 537..557 CDD:275368
C2H2 Zn finger 565..582 CDD:275368
MTF-1NP_001097560.1 zf-C2H2_aberr 329..471 CDD:293622 45/146 (31%)
C2H2 Zn finger 331..353 CDD:275368 6/25 (24%)
zf-H2C2_2 345..372 CDD:290200 8/27 (30%)
C2H2 Zn finger 361..383 CDD:275368 7/21 (33%)
zf-H2C2_2 375..402 CDD:290200 7/26 (27%)
C2H2 Zn finger 391..413 CDD:275368 7/21 (33%)
zf-C2H2 418..440 CDD:278523 10/21 (48%)
C2H2 Zn finger 420..440 CDD:275368 9/19 (47%)
zf-H2C2_2 432..458 CDD:290200 8/25 (32%)
COG5048 442..>519 CDD:227381 28/144 (19%)
C2H2 Zn finger 448..470 CDD:275368 6/21 (29%)
zf-H2C2_2 462..489 CDD:290200 13/58 (22%)
C2H2 Zn finger 478..500 CDD:275368 6/50 (12%)
DUF3682 862..>931 CDD:289231
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24377
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.100

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