DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8301 and CG10494

DIOPT Version :9

Sequence 1:	NP_649915.1	Gene:	CG8301 / 41160	FlyBaseID:	FBgn0037717	Length:	607	Species:	Drosophila melanogaster
Sequence 2:	NP_726079.1	Gene:	CG10494 / 37453	FlyBaseID:	FBgn0034634	Length:	523	Species:	Drosophila melanogaster

Alignment Length:	338	Identity:	68/338 - (20%)
Similarity:	111/338 - (32%)	Gaps:	93/338 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   319 HLM-CHEATH--SGTSSRKSEHCGFCG---KTF---IHLKTLRWHIYRQHGGEKPYKCA------ 368
            ||| ...|:|  |..||.|:..|.:..   :||   ||...|:..:.|.....|.::..
  Fly    23 HLMNLGNASHSVSENSSGKASRCKWTSAKVETFLEIIHQLKLQAALRRPRSNAKVFRMVSREMAR 87

  Fly   369 -NCTEVFASYAEKRIHMLERHRENLTAIERSECMLCRQPFSSEPDLIHHMSAEHLQRPGAPIIAN 432
             ||.: ...:...:.|.:.|             ...|.....||  ..|..|.|....|..:...
  Fly    88 RNCPK-SPKHLRVKFHQMRR-------------QYARARNGGEP--FEHFEAVHELMQGEDVSDL 136

  Fly   433 NKRVLQQKRERQYSGLFQCGSCSQRFNMKSALERHAAVHSEKDRPHACPHCSKRFKRAQDMKWHI 497
            ::..|:...:.:        :...:..|.|..|...|:.:.....:....|          ||
  Fly   137 DEEALESDSDME--------ADEDQSGMISETEGDDALDASGSSVNIVARC----------KW-- 181

  Fly   498 KTHEKEKPNVCDVCGKAFALKYVLTQHR-------LSHEVLEKNFKCNVCGRAYL---FEKSLRL 552
              .|.|...:.|:. ....|:..|.|.|       ||.|:.::|  |:. |...|   |::..||
  Fly   182 --AEGEVDLLLDLI-HTLGLRAALLQKRNAKVFKLLSKEMAKRN--CHK-GAEKLRIKFQQLRRL 240

  Fly   553 HQRTH--TGKTY-------YKCDLCQERFVTHIKLKTHMQKAH------------AASQPHSA-- 594
            :.:..  ||||:       ...|..:|......:.:.|:..|.            .|||...|
  Fly   241 YNKVKNGTGKTFEHFEAMRLVLDPTEEEAAADAEAEAHLSSASDSDFNDSDEEEGDASQRSGAHF 305

  Fly   595 --DQPLDDLINIV 605
              |:.:|..:.|:
  Fly   306 WTDEEVDSFLLII 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8301	NP_649915.1	zf-AD	3..87	CDD:285071
		COG5048	198..>508	CDD:227381	38/204 (19%)
		C2H2 Zn finger	221..241	CDD:275368
		C2H2 Zn finger	249..269	CDD:275368
		C2H2 Zn finger	277..297	CDD:275368
		C2H2 Zn finger	305..327	CDD:275368	4/8 (50%)
		C2H2 Zn finger	338..359	CDD:275368	7/26 (27%)
		C2H2 Zn finger	367..384	CDD:275368	2/23 (9%)
		C2H2 Zn finger	400..420	CDD:275368	4/19 (21%)
		C2H2 Zn finger	451..471	CDD:275368	4/19 (21%)
		C2H2 Zn finger	480..500	CDD:275368	3/19 (16%)
		C2H2 Zn finger	508..528	CDD:275368	6/26 (23%)
		C2H2 Zn finger	537..557	CDD:275368	6/22 (27%)
		C2H2 Zn finger	565..582	CDD:275368	2/16 (13%)
CG10494	NP_726079.1	Myb_DNA-bind_4	44..123	CDD:290549	16/94 (17%)
		Myb_DNA-bind_4	178..257	CDD:290549	24/96 (25%)
		Myb_DNA-bind_4	303..391	CDD:290549	4/16 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910