Protein Alignment CG8301 and Zfp846

DIOPT Version :10

• Sequence 1: NP_649915.1
• Gene: CG8301 / 41160
• FlyBaseID: FBgn0037717
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_001128057.1
• Gene: Zfp846 / 363022
• RGDID: 1564241
• Length: 547
• Species: Rattus norvegicus
• Alignment Length: 513
• Identity: 147/513 - (28%)
• Similarity: 224/513 - (43%)
• Gaps: 67/513 - (13%)

  Fly    97 SSLEDDEIGQEDLEPAEEHQETETT-------KPTTTVSAETQPNNTASDPI------EIFVDAV 148
            |.||::::.:|||:..|....|:.:       :..|:...:|..:::|.:..      |||
  Rat    64 SWLEEEDLHREDLQEWEMPLGTQESTLHQDFLRGQTSSGVQTGRSHSARELCYYTQCGEIF---- 124

  Fly   149 DIDEAEEEEEEEEQQQQYDEEVEEPIT----DESAPPQLTISYACKFCLRPQENYQLQQLLLEHI 209
                 .|....:...:.:.......:|    |.||......:|.||.|   .:.:.....|..|:
  Rat   125 -----SEHSYFKTHVKTHSAWNTGHLTHSDHDASAQVHTIKTYPCKIC---GKAFGRSSNLNRHL 181

  Fly   210 NASHDPEQPYNCPECEARFQDAASRTVHLKSSHVEKQHACGVCGKKYGDRHNLRHHVEKYHSETD 274
            . ||..|:||.|.||...|...:....|.::...||.:.|..|||.:..|..|..|:..:.||..
  Rat   182 R-SHTGEKPYECKECGKAFTTYSRLVEHFRTHTGEKPYKCKDCGKAFAKRSGLITHISTHASEKP 245

  Fly   275 FECALCEKRFYTRKSLNYHMKWHNPDRQFKCRHSGCERLFISQRHLMCHEA-THSGTSSRKSEHC 338
            |.|..|.|.|.:...|:.|::.|:.:|.:.|:.  |.|.|::..:|..|.. ||||   .:...|
  Rat   246 FACKECGKAFASSPRLSQHIRIHSGERPYICKE--CGRAFLTSSYLRNHVGRTHSG---ERPYIC 305

  Fly   339 GFCGKTFIHLKTLRWHIYRQHGGEKPYKCANCTEVFASYAEKRIHMLERHRENLTAIERSECMLC 403
            |.|||.|.....||.|: |.|.||:||.|..|.:.|.:.:....|:.:.|...:..|    |..|
  Rat   306 GECGKAFHSYSNLRRHV-RTHSGERPYICKECGKAFLNSSYLHNHIRKTHSGEMPHI----CGEC 365

  Fly   404 RQPFSSEPDLIHHMSAEHLQRPGAPIIANNKRVLQQKRERQYSGLFQCGSCSQRFNMKSALERHA 468
            .:.|.:...|..|:.....:||..                       |..|.:.|...|.|.:|.
  Rat   366 GKVFHASSYLRRHLRTHSGERPCI-----------------------CKECGKAFLNSSYLRKHL 407

  Fly   469 AVHSEKDRPHACPHCSKRFKRAQDMKWHIKTHEKEKPNVCDVCGKAFALKYVLTQHRLSHEVLEK 533
            .:|: .|:|:.|..|.|.::|...:..|:||||.|||..||||||:|.....||:|...| ...|
  Rat   408 TIHT-GDKPYECKDCGKAYRRYNLLHDHLKTHEVEKPFECDVCGKSFQYFSYLTKHIRIH-TGTK 470

  Fly   534 NFKCNVCGRAYLFEKSLRLHQRTHTGKTYYKCDLCQERFVTHIKLKTHMQKAHAASQP 591
            .:||..||:.:....|...|.|||||:..|:|..|::.|.:...|..|: |.||..:|
  Rat   471 PYKCKYCGKDFTTSSSRTEHIRTHTGERPYECMECEKTFTSSSNLIHHV-KIHAREKP 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8301	NP_649915.1	zf-AD	3..88	CDD:462262
		COG5048	198..>508	CDD:227381	91/310 (29%)
		C2H2 Zn finger	221..241	CDD:275368	5/19 (26%)
		C2H2 Zn finger	249..269	CDD:275368	7/19 (37%)
		C2H2 Zn finger	277..297	CDD:275368	6/19 (32%)
		C2H2 Zn finger	305..327	CDD:275368	6/22 (27%)
		C2H2 Zn finger	338..359	CDD:275368	10/20 (50%)
		C2H2 Zn finger	367..384	CDD:275368	3/16 (19%)
		C2H2 Zn finger	400..420	CDD:275368	5/19 (26%)
		C2H2 Zn finger	451..471	CDD:275368	6/19 (32%)
		C2H2 Zn finger	480..500	CDD:275368	6/19 (32%)
		C2H2 Zn finger	508..528	CDD:275368	10/19 (53%)
		SUF4-like	536..>586	CDD:411020	18/49 (37%)
		C2H2 Zn finger	537..558	CDD:411020	7/20 (35%)
		C2H2 Zn finger	537..557	CDD:275368	6/19 (32%)
		C2H2 Zn finger	565..586	CDD:411020	6/20 (30%)
		C2H2 Zn finger	565..582	CDD:275368	4/16 (25%)
Zfp846	NP_001128057.1	KRAB	14..70	CDD:214630	3/5 (60%)
		C2H2 Zn finger	118..137	CDD:275368	4/27 (15%)
		COG5048	160..528	CDD:227381	128/408 (31%)
		C2H2 Zn finger	164..184	CDD:275368	5/23 (22%)
		C2H2 Zn finger	192..212	CDD:275368	5/19 (26%)
		C2H2 Zn finger	220..240	CDD:275368	7/19 (37%)
		C2H2 Zn finger	248..268	CDD:275368	6/19 (32%)
		C2H2 Zn finger	276..297	CDD:275368	6/22 (27%)
		C2H2 Zn finger	305..325	CDD:275368	10/20 (50%)
		C2H2 Zn finger	333..354	CDD:275368	4/20 (20%)
		C2H2 Zn finger	362..382	CDD:275368	5/19 (26%)
		C2H2 Zn finger	390..410	CDD:275368	6/19 (32%)
		C2H2 Zn finger	418..438	CDD:275368	6/19 (32%)
		C2H2 Zn finger	446..466	CDD:275368	10/19 (53%)
		C2H2 Zn finger	474..494	CDD:275368	6/19 (32%)
		C2H2 Zn finger	502..522	CDD:275368	6/20 (30%)
		C2H2 Zn finger	530..547	CDD:275368