DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG8301 and CG1663

DIOPT Version :9

Sequence 1:NP_649915.1 Gene:CG8301 / 41160 FlyBaseID:FBgn0037717 Length:607 Species:Drosophila melanogaster
Sequence 2:NP_610521.1 Gene:CG1663 / 36012 FlyBaseID:FBgn0033449 Length:387 Species:Drosophila melanogaster


Alignment Length:430 Identity:95/430 - (22%)
Similarity:153/430 - (35%) Gaps:134/430 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   153 AEEEEEEEEQQQQYDEEVEEPITDESAPPQLTISYACKFCLRPQENYQLQQLLLEHINASHDPEQ 217
            |:|:|.::|.|.:....:...|..||...::            ||:::..:.:.|.:..:..||:
  Fly    16 ADEDEIQDEVQVEMTNLLAASIAQESKLAEV------------QESFKNVEFMEEEVEPNFSPEK 68

  Fly   218 PYNCPECEAR-FQDAASRTVHLKSSHVEKQHACGVC------------------GKKYGDRHNLR 263
            .....|..:. ..|..|...| |:.:..::.:.||.                  |....||.:..
  Fly    69 EQGHDELASNSHHDYISNQPH-KAFYSLQRTSPGVIQYFIQQLRRHKFFWITEHGINKKDRMDSS 132

  Fly   264 HHV-----EKYHSETDFECALCEKRF----YTRKSLNYHMKWHNPDRQFKCR-----HSGCERLF 314
            ..|     .::|.:.|.:......||    :.|:   |.|:..:.|  |:||     ||..:  |
  Fly   133 QKVAEALFHRFHFQLDPKVVNASARFLQVWFERQ---YVMQLSSSD--FRCRYPKYYHSLLK--F 190

  Fly   315 ISQRHL---MCHEATHSGTSSRKSEHCGFCGKTFIHLKTLRWHIYRQHGGEKPYKCANCTEVFAS 376
            :...|:   :|.|                |.:.|::.:.||.|.:|.|||..|            
  Fly   191 MPTNHISVTICEE----------------CDRRFLNERLLRLHKFRVHGGPNP------------ 227

  Fly   377 YAEKRIHMLERHRENLTAIERSECMLCRQPFSSEPDLIHHMSAEHLQRP---------GAPIIAN 432
                                 :.|.:|.|.|.....|..|.:..|.:||         .||    
  Fly   228 ---------------------NVCHVCHQSFPLASKLEQHQARYHFKRPEWQCSRCDYNAP---- 267

  Fly   433 NKRVLQQKR-----ERQYSGLFQCGSCSQRFNMKSALERHAAVHSEKDRPH-ACPHCSKRFKRAQ 491
            :|...||.:     :|.|.    |..|.......|||..|...|   |:|. .|||||::|:...
  Fly   268 SKWDFQQHQAMHAGQRNYI----CELCGHSSKTSSALAVHRRTH---DQPKLCCPHCSRQFRENS 325

  Fly   492 DMKWHI-KTHE--KEKPNVCDVCGKAFALKYVLTQHRLSH 528
            .:|.|| |.|:  ..:...||.|.:.|....:|..|:|.|
  Fly   326 TLKSHIRKIHDGNSARQVSCDFCWRRFKTLELLKLHKLVH 365

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8301NP_649915.1 zf-AD 3..87 CDD:285071
COG5048 198..>508 CDD:227381 77/363 (21%)
C2H2 Zn finger 221..241 CDD:275368 5/20 (25%)
C2H2 Zn finger 249..269 CDD:275368 6/42 (14%)
C2H2 Zn finger 277..297 CDD:275368 5/23 (22%)
C2H2 Zn finger 305..327 CDD:275368 8/29 (28%)
C2H2 Zn finger 338..359 CDD:275368 6/20 (30%)
C2H2 Zn finger 367..384 CDD:275368 0/16 (0%)
C2H2 Zn finger 400..420 CDD:275368 6/19 (32%)
C2H2 Zn finger 451..471 CDD:275368 6/19 (32%)
C2H2 Zn finger 480..500 CDD:275368 10/20 (50%)
C2H2 Zn finger 508..528 CDD:275368 7/19 (37%)
C2H2 Zn finger 537..557 CDD:275368
C2H2 Zn finger 565..582 CDD:275368
CG1663NP_610521.1 MttA_Hcf106 <33..>91 CDD:294511 12/70 (17%)
C2H2 Zn finger 201..222 CDD:275368 8/36 (22%)
C2H2 Zn finger 259..279 CDD:275368 5/23 (22%)
C2H2 Zn finger 287..307 CDD:275368 6/19 (32%)
C2H2 Zn finger 314..335 CDD:275368 10/20 (50%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24377
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.100

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