DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8301 and Plzf

DIOPT Version :9

Sequence 1:	NP_649915.1	Gene:	CG8301 / 41160	FlyBaseID:	FBgn0037717	Length:	607	Species:	Drosophila melanogaster
Sequence 2:	NP_001285862.1	Gene:	Plzf / 34622	FlyBaseID:	FBgn0032401	Length:	469	Species:	Drosophila melanogaster

Alignment Length:	327	Identity:	84/327 - (25%)
Similarity:	121/327 - (37%)	Gaps:	108/327 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   298 NPDRQFKCRHSGCERLFISQRHLMCHEATHSGTSSRKSEHCGFCGKTFIHLKTLRWHIYRQHGGE 362
            |||.:.|     .|.:|.:::.....:...:..||.|..:|..|
  Fly   152 NPDPEKK-----AEAVFENRQSYFKLKNPRAVKSSSKVNYCIGC--------------------- 190

  Fly   363 KPYKCANCTEVFASYAEKRIHMLERHRENLTAIERSE--CMLCRQPFSSEPDLIHHMSAEHLQRP 425
             .:||               :.:::..|::.:.|.|.  |.||...|....:...|:
  Fly   191 -DFKC---------------YQVQKMIEHMGSCEPSHLICSLCEVGFLDWREYDTHL-------- 231

  Fly   426 GAPIIANNKRVLQQKRERQYSG----LFQCGSCSQRFNMKSALERHAAVHSEKDRPHACPHCSKR 486
                             |::||    .|.|..|..|||.::||..|...|| .:.||.||||.|.
  Fly   232 -----------------RRHSGDLRKPFFCLQCGIRFNTRAALLVHQPKHS-TETPHICPHCGKG 278

  Fly   487 FKRAQDMKWHIKTHEKEKPNVCDVCGKAFALKYVLTQHRLSH-------------------EVLE 532
            ||..|.:..||..|..||..:|||||.:......|..|:|.|                   |.|:
  Fly   279 FKWKQGLSNHILVHNPEKQMLCDVCGYSTTHMKALKSHKLLHTGEFFACTVSGCKHRANRKENLK 343

  Fly   533 ---------KNFKCNVCGRAYLFEKSLRLHQRTHT--GKTYYKCDLCQERFVTH--IKLKTHMQK 584
                     ::|.|.|||..:...|:|:.|...||  |...|||.||  .|.:|  .|:|.|:|:
  Fly   344 LHIETHKQGRDFICEVCGCKFSQSKNLKRHALKHTENGPNRYKCQLC--GFSSHRSDKMKEHVQR 406

  Fly   585 AH 586
            .|
  Fly   407 VH 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8301	NP_649915.1	zf-AD	3..87	CDD:285071
		COG5048	198..>508	CDD:227381	50/215 (23%)
		C2H2 Zn finger	221..241	CDD:275368
		C2H2 Zn finger	249..269	CDD:275368
		C2H2 Zn finger	277..297	CDD:275368
		C2H2 Zn finger	305..327	CDD:275368	2/21 (10%)
		C2H2 Zn finger	338..359	CDD:275368	2/20 (10%)
		C2H2 Zn finger	367..384	CDD:275368	1/16 (6%)
		C2H2 Zn finger	400..420	CDD:275368	5/19 (26%)
		C2H2 Zn finger	451..471	CDD:275368	8/19 (42%)
		C2H2 Zn finger	480..500	CDD:275368	10/19 (53%)
		C2H2 Zn finger	508..528	CDD:275368	8/19 (42%)
		C2H2 Zn finger	537..557	CDD:275368	7/19 (37%)
		C2H2 Zn finger	565..582	CDD:275368	7/18 (39%)
Plzf	NP_001285862.1	COG5048	<193..403	CDD:227381	70/252 (28%)
		C2H2 Zn finger	214..234	CDD:275368	6/44 (14%)
		C2H2 Zn finger	244..264	CDD:275368	8/19 (42%)
		C2H2 Zn finger	272..292	CDD:275368	10/19 (53%)
		C2H2 Zn finger	300..320	CDD:275368	8/19 (42%)
		C2H2 Zn finger	330..349	CDD:275368	2/18 (11%)
		C2H2 Zn finger	357..377	CDD:275368	7/19 (37%)
		C2H2 Zn finger	387..408	CDD:275368	9/22 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446615
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930