DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8301 and crol

DIOPT Version :9

Sequence 1:	NP_649915.1	Gene:	CG8301 / 41160	FlyBaseID:	FBgn0037717	Length:	607	Species:	Drosophila melanogaster
Sequence 2:	NP_001245993.1	Gene:	crol / 34592	FlyBaseID:	FBgn0020309	Length:	962	Species:	Drosophila melanogaster

Alignment Length:	417	Identity:	117/417 - (28%)
Similarity:	199/417 - (47%)	Gaps:	56/417 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   187 YACKFCLRPQENYQLQQLLLEHINASHDPEQPYNCPECEARFQDAASRTVHLKSSHV----EKQH 247
            :.|::|.:   .:..::.::.|:. .|..|.|:.|..|:..|    :|..|..:.::    :..|
  Fly   333 FRCQYCAK---TFTRKEHMVNHVR-KHTGETPHRCDICKKSF----TRKEHYVNHYMWHTGQTPH 389

  Fly   248 ACGVCGKKYGDRHNLRHHVEKYHSETDFECALCEKRFYTRKSLNYHMKWHNPDRQFKCRHSGCER 312
            .|.||||||..:.:|.:|:..:.:||.|.|.:|.|.|..::....|:.||..:...:|  ..|.:
  Fly   390 QCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTGETPHRC--DFCSK 452

  Fly   313 LFISQRHLMCHEATHSGTSSRKSEHCGFCGKTFIHLKTLRWHIYRQHGGEKPYKCANCTEVFASY 377
            .|..:.||:.|...|:|.|..:   |.:|.|||...:.|..|| |||.||.|:||..||:.|.
  Fly   453 TFTRKEHLLNHVRQHTGESPHR---CSYCMKTFTRKEHLVNHI-RQHTGETPFKCTYCTKAFT-- 511

  Fly   378 AEKRIHMLERHRENLTAIERSECMLCRQPFSSEPDLIHHMSAEHLQRPGAPIIANNKRVLQQKRE 442
              ::.||:...|:: |.....:|..|.:.|:.:..|.:|:
  Fly   512 --RKDHMVNHVRQH-TGESPHKCTYCTKTFTRKEHLTNHV------------------------- 548

  Fly   443 RQYSG--LFQCGSCSQRFNMKSALERHAAVHSEKDRPHACPHCSKRFKRAQDMKWHIKTHEKEKP 505
            ||::|  ..:|..|.:.|..|..|..|..:|: .|.||.|.:|.|.|.|.:.:..|::.|..:.|
  Fly   549 RQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHT-GDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNP 612

  Fly   506 NVCDVCGKAFALKYVLTQHRLSHEVLEKNFKCNVCGRAYLFEKSLRLHQRTHT-GKTY---YKCD 566
            :.|:||.|.|..|..|..|.......::.|.|..||:::..:.:|..|||:|| |:..   :.|:
  Fly   613 HCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFACE 677

  Fly   567 LCQERFVTHIKLKTHMQKAHAASQPHS 593
            .|.:.|:....|.:|| ::|:..:||:
  Fly   678 KCPKNFICKGHLVSHM-RSHSGEKPHA 703

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8301	NP_649915.1	zf-AD	3..87	CDD:285071
		COG5048	198..>508	CDD:227381	87/315 (28%)
		C2H2 Zn finger	221..241	CDD:275368	5/19 (26%)
		C2H2 Zn finger	249..269	CDD:275368	9/19 (47%)
		C2H2 Zn finger	277..297	CDD:275368	5/19 (26%)
		C2H2 Zn finger	305..327	CDD:275368	6/21 (29%)
		C2H2 Zn finger	338..359	CDD:275368	9/20 (45%)
		C2H2 Zn finger	367..384	CDD:275368	4/16 (25%)
		C2H2 Zn finger	400..420	CDD:275368	5/19 (26%)
		C2H2 Zn finger	451..471	CDD:275368	6/19 (32%)
		C2H2 Zn finger	480..500	CDD:275368	6/19 (32%)
		C2H2 Zn finger	508..528	CDD:275368	8/19 (42%)
		C2H2 Zn finger	537..557	CDD:275368	7/19 (37%)
		C2H2 Zn finger	565..582	CDD:275368	4/16 (25%)
crol	NP_001245993.1	C2H2 Zn finger	223..243	CDD:275368
		C2H2 Zn finger	251..271	CDD:275368
		C2H2 Zn finger	279..299	CDD:275368
		COG5048	300..723	CDD:227381	117/417 (28%)
		C2H2 Zn finger	307..327	CDD:275368
		C2H2 Zn finger	335..355	CDD:275368	3/23 (13%)
		C2H2 Zn finger	363..383	CDD:275368	5/23 (22%)
		C2H2 Zn finger	391..411	CDD:275368	9/19 (47%)
		C2H2 Zn finger	419..439	CDD:275368	5/19 (26%)
		C2H2 Zn finger	447..467	CDD:275368	6/21 (29%)
		C2H2 Zn finger	475..495	CDD:275368	9/20 (45%)
		C2H2 Zn finger	503..523	CDD:275368	7/23 (30%)
		C2H2 Zn finger	531..551	CDD:275368	6/44 (14%)
		C2H2 Zn finger	559..579	CDD:275368	6/19 (32%)
		C2H2 Zn finger	587..607	CDD:275368	6/19 (32%)
		C2H2 Zn finger	615..636	CDD:275368	8/20 (40%)
		C2H2 Zn finger	644..664	CDD:275368	7/19 (37%)
		C2H2 Zn finger	676..696	CDD:275368	6/20 (30%)
		C2H2 Zn finger	704..722	CDD:275368	117/417 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446618
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930