DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8301 and AgaP_AGAP012835

DIOPT Version :9

Sequence 1:	NP_649915.1	Gene:	CG8301 / 41160	FlyBaseID:	FBgn0037717	Length:	607	Species:	Drosophila melanogaster
Sequence 2:	XP_561485.2	Gene:	AgaP_AGAP012835 / 3292645	VectorBaseID:	AGAP012835	Length:	244	Species:	Anopheles gambiae

Alignment Length:	257	Identity:	55/257 - (21%)
Similarity:	96/257 - (37%)	Gaps:	57/257 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 ICSDCFTKFCSINAFRLAC------------------QEAQLK-----LSHIYDKIDASSLEDDE 103
            ||..|..|.....|:|..|                  ::::.|     ..|.|.::|.    |.|
Mosquito    17 ICEPCHNKLQKFTAYRYFCLSNDERFRELFSALCASERDSEAKPPSATFEHSYFRMDG----DSE 77

  Fly   104 IGQEDLEPAEEHQETETTKPTTTVSAETQPNNTASDPIEIFVDAVDIDEAEEEEEEEEQQQQYDE 168
            ..:|.:|..|..::..:.:.....||.|.|:     |.|..:...:::|.|..|:.::.::.|..
Mosquito    78 YPEEHVEMLEPTEQQHSDEGLNWWSATTPPS-----PSEAELSTEELEEFEPPEKPKKPRKPYVR 137

  Fly   169 EVEEPITDESAPPQLTISYACKFCLRPQENYQLQQLLLEHINASHDPEQPYNCPECEARFQDAAS 233
            ........:|:..:..:     :..||.:|...::|                |..| .:|  .|:
Mosquito   138 RATVGKEQDSSMKKQRV-----YKKRPNQNKLPKKL----------------CTVC-GKF--VAN 178

  Fly   234 RTVHLKSSHVEKQHACGVCGKKYGDRHNLRHHVEKYH-SETDFECALCEKRFYTRKSLNYHM 294
            ...||.|...|::.||..|...:.....|:.|||..| .:|...|.||::.|..:.|...||
Mosquito   179 LNHHLLSHTNERRFACTYCPGAFSRSSLLKVHVEAVHLKKTAKTCELCDRSFTHKSSYTIHM 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8301	NP_649915.1	zf-AD	3..87	CDD:285071	8/47 (17%)
		COG5048	198..>508	CDD:227381	26/98 (27%)
		C2H2 Zn finger	221..241	CDD:275368	6/19 (32%)
		C2H2 Zn finger	249..269	CDD:275368	6/19 (32%)
		C2H2 Zn finger	277..297	CDD:275368	7/18 (39%)
		C2H2 Zn finger	305..327	CDD:275368
		C2H2 Zn finger	338..359	CDD:275368
		C2H2 Zn finger	367..384	CDD:275368
		C2H2 Zn finger	400..420	CDD:275368
		C2H2 Zn finger	451..471	CDD:275368
		C2H2 Zn finger	480..500	CDD:275368
		C2H2 Zn finger	508..528	CDD:275368
		C2H2 Zn finger	537..557	CDD:275368
		C2H2 Zn finger	565..582	CDD:275368
AgaP_AGAP012835	XP_561485.2	zf-AD	<9..44	CDD:214871	7/26 (27%)
		C2H2 Zn finger	169..186	CDD:275368	6/19 (32%)
		C2H2 Zn finger	194..215	CDD:275368	6/20 (30%)
		C2H2 Zn finger	223..240	CDD:275368	5/16 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000098
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000