DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8301 and AgaP_AGAP012816

DIOPT Version :9

Sequence 1:	NP_649915.1	Gene:	CG8301 / 41160	FlyBaseID:	FBgn0037717	Length:	607	Species:	Drosophila melanogaster
Sequence 2:	XP_561173.5	Gene:	AgaP_AGAP012816 / 3292578	VectorBaseID:	AGAP012816	Length:	254	Species:	Anopheles gambiae

Alignment Length:	242	Identity:	41/242 - (16%)
Similarity:	78/242 - (32%)	Gaps:	83/242 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 PNDGLPQKICSDCFTKFCSINAFRLACQEAQLKLSHIYDKIDASSLEDDEIGQEDLEPAEEHQET 118
            |:|.....||.:|.........||.||                  :.:|...::....|...::.
Mosquito    49 PDDANGLAICFECLGSLKKSADFRYAC------------------IRNDSTFRQLSAEAAACRKG 95

  Fly   119 ETTKPTTTVSAETQPNNTASDPIEIFVDAVDIDEAEEEEEEEEQ--------------------Q 163
            ..|||     .:...:..::||:|:..:.:..:|...|..:|:|                    :
Mosquito    96 NPTKP-----VDHSEHIVSADPLELKFEIIYHEEDSLEPVDEDQLVRSIVNESFCADGATQGAAE 155

  Fly   164 QQYDE---EVEEPITDESAPPQLTISYACKFCLRPQENYQLQQLLLEHINASHDP---------- 215
            :.|..   |:.||::|.:                 :||...:...:.:..|..|.
Mosquito   156 EAYSANHIELGEPMSDAN-----------------EENDAFESHRIMNYRAGTDSLNTRRTRKPR 203

  Fly   216 --EQPYNCPECEARFQDAASRTVH--LKSSHVEKQHACGVCGKKYGD 258
              :.|...||      |..|.:|.  ::..:..::..|.:|||...|
Mosquito   204 KRKPPNGEPE------DLPSSSVEGKVRKKYDRRKVLCHLCGKTVAD 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8301	NP_649915.1	zf-AD	3..87	CDD:285071	9/32 (28%)
		COG5048	198..>508	CDD:227381	14/75 (19%)
		C2H2 Zn finger	221..241	CDD:275368	5/21 (24%)
		C2H2 Zn finger	249..269	CDD:275368	5/10 (50%)
		C2H2 Zn finger	277..297	CDD:275368
		C2H2 Zn finger	305..327	CDD:275368
		C2H2 Zn finger	338..359	CDD:275368
		C2H2 Zn finger	367..384	CDD:275368
		C2H2 Zn finger	400..420	CDD:275368
		C2H2 Zn finger	451..471	CDD:275368
		C2H2 Zn finger	480..500	CDD:275368
		C2H2 Zn finger	508..528	CDD:275368
		C2H2 Zn finger	537..557	CDD:275368
		C2H2 Zn finger	565..582	CDD:275368
AgaP_AGAP012816	XP_561173.5	zf-AD	11..84	CDD:214871	10/52 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000098
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000