DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8301 and AgaP_AGAP011408

DIOPT Version :9

Sequence 1:	NP_649915.1	Gene:	CG8301 / 41160	FlyBaseID:	FBgn0037717	Length:	607	Species:	Drosophila melanogaster
Sequence 2:	XP_554830.1	Gene:	AgaP_AGAP011408 / 3291312	VectorBaseID:	AGAP011408	Length:	309	Species:	Anopheles gambiae

Alignment Length:	362	Identity:	78/362 - (21%)
Similarity:	125/362 - (34%)	Gaps:	101/362 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   185 ISYACKFCLRPQENYQLQQLLLEHINASHDPEQPYNCPECEARFQDAASRTVHLKSSHVEKQHAC 249
            |.|.|:|||  .||   |:|||..:                        :|.....:..:.|...
Mosquito     8 ILYVCRFCL--CEN---QKLLLPLV------------------------KTFDTLLTIEDVQRFT 43

  Fly   250 GVCGKKYGDRHNLRHHVEKYHSETDFECALCEKRFYTRKSLNYHMKWHNPDRQFKCRHSGCERLF 314
            |:    ..|.:||::.:          |..|..:.  :.|.::..:..:.|.||:..|   :.|.
Mosquito    44 GI----QLDANNLQYAI----------CLECTNQL--KISADFRTRCLSNDAQFQQLH---DLLV 89

  Fly   315 ISQRHLMCHEATHSGTS------------------SRKSEH------------CGFCGKTFIHLK 349
            .|...:  ...|..|.|                  .|.:|:            |.|..:..:..:
Mosquito    90 ASANDI--ETKTEDGKSQLSDLDEPYMMAELDNFDDRSTEYSINDPFRRVQGECSFLEEYLLDSE 152

  Fly   350 TLRWHIYRQHGGEKPYKCANCTEVFASYAEKRIHMLERHRENLTAIERSECMLCRQPFSSEPDLI 414
            :   ...|..||.:    .:.|...:....:||...:.|..:...|...|.::......|:|:
Mosquito   153 S---DSLRVDGGRR----ISTTNRSSRTVSERIAKDDEHWNSANYIAPGEALISDDDGVSDPE-- 208

  Fly   415 HHMSAEHLQRPGAPIIANNKRVLQQKRERQYSGLFQCGSCSQRFNMKSALERHAAVHSEKDRPHA 479
             :........|..|:|      :..:|||....|..|..|.  ..:|..| :|...| |.|...|
Mosquito   209 -NGEWSSYYWPSNPLI------VPYERERGKRKLHLCHICG--IFVKDFL-KHVINH-EDDITEA 262

  Fly   480 CPHCSKRFKRAQDMKWHIKT-HEKEKPNVCDVCGKAF 515
            ||||..|.|:..:|..||:| |.|.....|::|||.|
Mosquito   263 CPHCPVRMKQKTNMIAHIQTVHLKTISKTCEICGKGF 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8301	NP_649915.1	zf-AD	3..87	CDD:285071
		COG5048	198..>508	CDD:227381	66/340 (19%)
		C2H2 Zn finger	221..241	CDD:275368	1/19 (5%)
		C2H2 Zn finger	249..269	CDD:275368	4/19 (21%)
		C2H2 Zn finger	277..297	CDD:275368	3/19 (16%)
		C2H2 Zn finger	305..327	CDD:275368	3/21 (14%)
		C2H2 Zn finger	338..359	CDD:275368	3/20 (15%)
		C2H2 Zn finger	367..384	CDD:275368	3/16 (19%)
		C2H2 Zn finger	400..420	CDD:275368	2/19 (11%)
		C2H2 Zn finger	451..471	CDD:275368	5/19 (26%)
		C2H2 Zn finger	480..500	CDD:275368	10/20 (50%)
		C2H2 Zn finger	508..528	CDD:275368	5/8 (63%)
		C2H2 Zn finger	537..557	CDD:275368
		C2H2 Zn finger	565..582	CDD:275368
AgaP_AGAP011408	XP_554830.1	zf-AD	11..83	CDD:214871	22/116 (19%)
		C2H2 Zn finger	238..255	CDD:275368	5/19 (26%)
		C2H2 Zn finger	263..284	CDD:275368	10/20 (50%)
		C2H2 Zn finger	292..309	CDD:275368	5/8 (63%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000098
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000