DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8301 and Zscan10

DIOPT Version :9

Sequence 1:	NP_649915.1	Gene:	CG8301 / 41160	FlyBaseID:	FBgn0037717	Length:	607	Species:	Drosophila melanogaster
Sequence 2:	NP_001100451.1	Gene:	Zscan10 / 302962	RGDID:	1310745	Length:	778	Species:	Rattus norvegicus

Alignment Length:	561	Identity:	137/561 - (24%)
Similarity:	215/561 - (38%)	Gaps:	132/561 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 DEIGQEDLEPAEEHQETETTKP-------TTTVSAETQPNNTASDPIEIFVDAVDIDEAEEEEEE 159
            :|:..|:.:||....|::|.||       |.|:..||...::...|.:
  Rat   270 EELKVEERKPAAIGAESQTDKPGGAGEPLTQTLGKETSSPDSGGTPAD----------------- 317

  Fly   160 EEQQQQYDEEVEEPITDESAPPQLTISYACKFCLRPQENYQLQQLLLEHINASHDPEQP------ 218
                  ..|.||...|.::..||..:.:.|..|   ..|:.....|..|...||...||
  Rat   318 ------SGEVVEVRGTADAPKPQAEVQFICTAC---GVNFSQMSHLQAHQLQSHPSSQPHPSSRS 373

  Fly   219 YNCPECEARFQDAASRTVHLKSSHVEKQHACGVCGKKYGDRHNLRHHVEKYHSETDFECALCEKR 283
            :.|..|...|..::...:|:::...|:.|||.:|..::....:||.|:..:.||..|.||.|.:.
  Rat   374 FRCLWCGKTFGRSSILKLHMRTHTDERPHACHLCSHRFRQSSHLRKHLLTHFSEPTFRCAECNQG 438

  Fly   284 FYTRKSLNYHMKWH--------NPDRQFK--------CRHSG--CERLFISQRHLMCHE------ 324
            |..|.||..|:..|        ||:.:.|        |.|.|  .:|....:|||..|.
  Rat   439 FRRRSSLMQHLMAHAQEQIPTPNPEGKTKVPAVAAVLCSHCGQTFQRRSSLKRHLRIHAKDKDHH 503

  Fly   325 ---------ATHSGTSS----------RKSEH---------------CGFCGKTFIHLKTLRWHI 355
                     ::|..:.|          |:|||               |..||:.|.....|..|
  Rat   504 QSSEDPGNLSSHQESESYVCSDCGKVFRQSEHLITHRRVHTRERPFSCQVCGRCFTQNSQLINH- 567

  Fly   356 YRQHGGEKPYKCANCTEVFASYAEKRIHMLERHRENLTAIERSECMLCRQPFSSEPDLIHHMSAE 420
            .:.|.||||:.|..|::.|...|.     |.||......:....|..|.:.|....||..|:...
  Rat   568 QQVHTGEKPHACPQCSKRFVRRAG-----LARHLLTHGGLRPYHCAQCGKSFCQMRDLTRHLRCH 627

  Fly   421 HLQRPGAPIIANNKRVLQQKRERQYSGLFQCGSCSQRFNMKSALERHAAVHSEKDRPHACPHCSK 485
            ..::|                       .:|..|.:.|:..:.|.||..:|: .::||||..|..
  Rat   628 TGEKP-----------------------CRCNECGEGFSQNAHLARHRRIHT-GEKPHACDTCGH 668

  Fly   486 RFKRAQDMKWHIKTHEKEKPNVCDVCGKAFALKYVLTQHRLSH----EVLEKNFKCNVCGRAYLF 546
            ||:.:.::..|.::|..|:|..|..||::|.....|.:|.::|    :..|...:|..||:::..
  Rat   669 RFRNSSNLARHRRSHTGERPYSCPTCGRSFRRNAHLQRHLVTHTGSKQETEDPQECPECGKSFNR 733

  Fly   547 EKSLRLHQRTHTGKTYYKCDLCQERFVTHIKLKTHMQKAHA 587
            ..:|..|...|||...|.|.||...|..:..|..|: :.||
  Rat   734 SSNLLRHLLLHTGARPYSCVLCGRGFSRNSHLLRHL-RTHA 773

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8301	NP_649915.1	zf-AD	3..87	CDD:285071
		COG5048	198..>508	CDD:227381	91/373 (24%)
		C2H2 Zn finger	221..241	CDD:275368	4/19 (21%)
		C2H2 Zn finger	249..269	CDD:275368	5/19 (26%)
		C2H2 Zn finger	277..297	CDD:275368	8/19 (42%)
		C2H2 Zn finger	305..327	CDD:275368	8/38 (21%)
		C2H2 Zn finger	338..359	CDD:275368	6/20 (30%)
		C2H2 Zn finger	367..384	CDD:275368	4/16 (25%)
		C2H2 Zn finger	400..420	CDD:275368	6/19 (32%)
		C2H2 Zn finger	451..471	CDD:275368	6/19 (32%)
		C2H2 Zn finger	480..500	CDD:275368	5/19 (26%)
		C2H2 Zn finger	508..528	CDD:275368	6/19 (32%)
		C2H2 Zn finger	537..557	CDD:275368	5/19 (26%)
		C2H2 Zn finger	565..582	CDD:275368	5/16 (31%)
Zscan10	NP_001100451.1	SCAN	39..123	CDD:153421
		C2H2 Zn finger	341..368	CDD:275368	8/29 (28%)
		COG5048	347..770	CDD:227381	114/453 (25%)
		C2H2 Zn finger	376..396	CDD:275368	4/19 (21%)
		C2H2 Zn finger	404..424	CDD:275368	5/19 (26%)
		C2H2 Zn finger	432..452	CDD:275368	8/19 (42%)
		C2H2 Zn finger	476..496	CDD:275368	7/19 (37%)
		zf-C2H2	521..543	CDD:278523	4/21 (19%)
		C2H2 Zn finger	523..543	CDD:275368	4/19 (21%)
		zf-H2C2_2	535..560	CDD:290200	5/24 (21%)
		C2H2 Zn finger	551..571	CDD:275368	6/20 (30%)
		zf-H2C2_2	564..588	CDD:290200	10/24 (42%)
		C2H2 Zn finger	579..599	CDD:275368	7/24 (29%)
		C2H2 Zn finger	607..627	CDD:275368	6/19 (32%)
		zf-H2C2_2	619..644	CDD:290200	7/47 (15%)
		C2H2 Zn finger	635..655	CDD:275368	6/19 (32%)
		zf-H2C2_2	647..672	CDD:290200	11/25 (44%)
		C2H2 Zn finger	663..683	CDD:275368	5/19 (26%)
		zf-H2C2_2	675..700	CDD:290200	8/24 (33%)
		C2H2 Zn finger	691..711	CDD:275368	6/19 (32%)
		zf-C2H2	723..744	CDD:278523	5/20 (25%)
		C2H2 Zn finger	724..744	CDD:275368	5/19 (26%)
		zf-C2H2	750..772	CDD:278523	7/22 (32%)
		C2H2 Zn finger	752..772	CDD:275368	6/20 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24377
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100