DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8301 and Zfp641

DIOPT Version :9

Sequence 1:	NP_649915.1	Gene:	CG8301 / 41160	FlyBaseID:	FBgn0037717	Length:	607	Species:	Drosophila melanogaster
Sequence 2:	NP_001100262.1	Gene:	Zfp641 / 300197	RGDID:	1310412	Length:	421	Species:	Rattus norvegicus

Alignment Length:	186	Identity:	55/186 - (29%)
Similarity:	77/186 - (41%)	Gaps:	35/186 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   227 RFQDAASRTVHLKSSHVE---KQHACGVCGKKYGDRHNLRHHVEKYHSETDFECALCEKRFYTRK 288
            ||....|.:..|:|:..:   |.|.|..|||::....:|..|.:.:..|..:.|..|||.|..|.
  Rat   227 RFLQEDSVSHLLRSTDTDSLLKPHTCPQCGKQFVWGSHLARHQQTHTGERPYSCLKCEKSFGRRH 291

  Fly   289 SLNYHMKWHNPDRQFKCRHSGCERLFISQRHLMCHEATHSGTSSRKSEH---------------- 337
            .|..|.|.|..|:..:|..  |.:.|....||..|:..|:.:.|.|.:.
  Rat   292 HLIRHQKTHLHDKPSRCPE--CGKTFRCSSHLASHQRVHADSKSCKGQEIGESPGAQCAPPVPKC 354

  Fly   338 --CGFCGKTFIHLKTLRWHIYRQ---HGGEKPYKCANCTEVFASYAEKRIHMLERH 388
              |..|||:|    ..|.|:.|.   |.||||:.|..|.:.|.     |.|.|:||
  Rat   355 HVCTECGKSF----GRRHHLVRHWLTHTGEKPFHCPRCEKSFG-----RKHHLDRH 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8301	NP_649915.1	zf-AD	3..87	CDD:285071
		COG5048	198..>508	CDD:227381	55/186 (30%)
		C2H2 Zn finger	221..241	CDD:275368	4/13 (31%)
		C2H2 Zn finger	249..269	CDD:275368	6/19 (32%)
		C2H2 Zn finger	277..297	CDD:275368	9/19 (47%)
		C2H2 Zn finger	305..327	CDD:275368	6/21 (29%)
		C2H2 Zn finger	338..359	CDD:275368	8/23 (35%)
		C2H2 Zn finger	367..384	CDD:275368	4/16 (25%)
		C2H2 Zn finger	400..420	CDD:275368
		C2H2 Zn finger	451..471	CDD:275368
		C2H2 Zn finger	480..500	CDD:275368
		C2H2 Zn finger	508..528	CDD:275368
		C2H2 Zn finger	537..557	CDD:275368
		C2H2 Zn finger	565..582	CDD:275368
Zfp641	NP_001100262.1	PLN03206	<13..90	CDD:178745
		KRAB	95..156	CDD:214630
		COG5048	<208..402	CDD:227381	55/186 (30%)
		C2H2 Zn finger	252..272	CDD:275368	6/19 (32%)
		C2H2 Zn finger	280..300	CDD:275368	9/19 (47%)
		C2H2 Zn finger	308..328	CDD:275368	6/21 (29%)
		C2H2 Zn finger	357..377	CDD:275368	8/23 (35%)
		C2H2 Zn finger	385..405	CDD:275368	8/22 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24377
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100