DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8301 and Zfp641

DIOPT Version :9

Sequence 1:	NP_649915.1	Gene:	CG8301 / 41160	FlyBaseID:	FBgn0037717	Length:	607	Species:	Drosophila melanogaster
Sequence 2:	NP_776130.1	Gene:	Zfp641 / 239652	MGIID:	2442788	Length:	422	Species:	Mus musculus

Alignment Length:	187	Identity:	58/187 - (31%)
Similarity:	81/187 - (43%)	Gaps:	36/187 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   227 RF--QDAASRTVH-LKSSHVEKQHACGVCGKKYGDRHNLRHHVEKYHSETDFECALCEKRFYTRK 288
            ||  :|..||.:| ..:..:.|.|.|..|||::....:|..|.:.:..|..:.|..|||.|..|.
Mouse   227 RFLQEDTFSRHLHRTDTDSLLKPHTCPQCGKQFVWGSHLARHQQTHTGERPYSCLKCEKSFGRRH 291

  Fly   289 SLNYHMKWHNPDRQFKCRHSGCERLFISQRHLMCHEATHSGTSSRK---------SEH------- 337
            .|..|.|.|..|:..:|  |.|.:.|....||..|:..|:.:.|.|         ::|
Mouse   292 HLIRHQKTHLHDKPSRC--SECGKSFRCSSHLASHQRVHADSKSCKGQDFGESPAAQHCVPPVPK 354

  Fly   338 ---CGFCGKTFIHLKTLRWHIYRQ---HGGEKPYKCANCTEVFASYAEKRIHMLERH 388
               |..|||:|    ..|.|:.|.   |.||||:.|..|.:.|.     |.|.|:||
Mouse   355 CHVCTECGKSF----GRRHHLVRHWLTHTGEKPFHCPRCEKSFG-----RKHHLDRH 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8301	NP_649915.1	zf-AD	3..87	CDD:285071
		COG5048	198..>508	CDD:227381	58/187 (31%)
		C2H2 Zn finger	221..241	CDD:275368	6/16 (38%)
		C2H2 Zn finger	249..269	CDD:275368	6/19 (32%)
		C2H2 Zn finger	277..297	CDD:275368	9/19 (47%)
		C2H2 Zn finger	305..327	CDD:275368	7/21 (33%)
		C2H2 Zn finger	338..359	CDD:275368	8/23 (35%)
		C2H2 Zn finger	367..384	CDD:275368	4/16 (25%)
		C2H2 Zn finger	400..420	CDD:275368
		C2H2 Zn finger	451..471	CDD:275368
		C2H2 Zn finger	480..500	CDD:275368
		C2H2 Zn finger	508..528	CDD:275368
		C2H2 Zn finger	537..557	CDD:275368
		C2H2 Zn finger	565..582	CDD:275368
Zfp641	NP_776130.1	PLN03206	<2..90	CDD:178745
		KRAB	95..155	CDD:214630
		Transactivation. /evidence=ECO:0000250	157..251		7/23 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	172..191
		COG5048	<237..407	CDD:227381	53/177 (30%)
		C2H2 Zn finger	252..272	CDD:275368	6/19 (32%)
		C2H2 Zn finger	280..300	CDD:275368	9/19 (47%)
		C2H2 Zn finger	308..328	CDD:275368	7/21 (33%)
		C2H2 Zn finger	358..378	CDD:275368	8/23 (35%)
		C2H2 Zn finger	386..406	CDD:275368	8/22 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24377
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100