Protein Alignment CG8301 and Zfp472

DIOPT Version :10

• Sequence 1: NP_649915.1
• Gene: CG8301 / 41160
• FlyBaseID: FBgn0037717
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_694703.2
• Gene: Zfp472 / 224691
• MGIID: 2385049
• Length: 534
• Species: Mus musculus
• Alignment Length: 528
• Identity: 134/528 - (25%)
• Similarity: 203/528 - (38%)
• Gaps: 123/528 - (23%)

  Fly   142 EIFVDAVDIDEAEEEEEEEEQQQ--------------QYD---------EEVEEPITDESAPPQL 183
            |.|::.:.|.:.|||:.|||.|.              :||         ::..|.:.:|..||.:
Mouse    41 ETFLNLISIGKTEEEDTEEEYQNPKGNLRTLMVERLCKYDYGNQYGETHQQSPEHVANEKMPPAI 105

  Fly   184 TI--------------------SYACKF------CLRPQ---ENYQLQQLLLEH----------- 208
            |.                    ..:|::      .|:.:   :::...:||..|
Mouse   106 TECERDICTHLPSDMHFKGQTGKKSCQYQEHTEKALKHKNCWKDFTYSELLWMHKSPPMRQKPYE 170

  Fly   209 ----------INASHD------PEQPYNCPECEARFQDAASRTVHLKSSHVEKQHACGVCGKKYG 257
                      ....||      .|:.|.|.:|...:.|:.|...|.:|...||:|.|..|||.:.
Mouse   171 DKQGTEASRSFTTDHDYEGAYTEEKSYICKQCGKAWSDSCSLLWHERSHIQEKRHTCKQCGKAFS 235

  Fly   258 DRHNLRHHVEKYHSETDFECALCEKRFYTRKSLNYHMKWHNPDRQFKCRHSGCERLFISQRHLMC 322
            ....|..|...:..|..:.|..|.|.|..|::.:.|.:.|...:.|.|:.  |.:.|:....|:.
Mouse   236 RPSQLHKHERIHTGEKPYVCTHCGKAFIDRRTCHNHERTHTGVKPFACKQ--CGKAFLRSCQLLI 298

  Fly   323 HEATHSGTSSRKSEHCGFCGKTFIHLKTLRWHIYRQHGGEKPYKCANCTEVFASYAEKRIHMLER 387
            ||..|:|   .:...|..|||.|.:.....:| .|.|.||||..|..|.:.|...|...||
Mouse   299 HERIHTG---ERPFVCKHCGKAFTYSSACYYH-ERIHTGEKPCVCKQCGKAFKCSAYLHIH---- 355

  Fly   388 HRENLTAIERSECMLCRQPFSSEPDLIHHMSAEHLQRPGAPIIANNKRVLQQKRERQYSG--LFQ 450
                    |||..       ..:|.:..|.........|.           .|.||.::|  .:.
Mouse   356 --------ERSHS-------GEKPYVCKHCGKAFAYATGC-----------HKHERIHTGEKPYM 394

  Fly   451 CGSCSQRFNMKSALERHAAVHSEKDRPHACPHCSKRFKRAQDMKWHIKTHEKEKPNVCDVCGKAF 515
            |..|.:.|....:|..|...|| .::|:.|..|.|.|.:...::.|.:.|..|||.||..|||||
Mouse   395 CVQCGKLFTFPRSLHIHERSHS-GEKPYVCKQCGKSFTQGTSLRRHERIHTGEKPYVCKQCGKAF 458

  Fly   516 ALKYVLTQHRLSHEVLEKNFKCNVCGRAYLFEKSLRLHQRTHTGKTYYKCDLCQERFVTHIKL-- 578
            ..:.....|..:| ..||.|.|..||:.:.|.|||::|::.|||:..|.|..|.:.|.....|
Mouse   459 IQRDDCYSHERTH-TGEKPFMCVQCGKTFTFSKSLQIHEKNHTGEKPYICKQCGKAFTCSTYLLR 522

  Fly   579 --KTHMQK 584
              :||.:|
Mouse   523 HERTHSEK 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8301	NP_649915.1	zf-AD	3..88	CDD:462262
		COG5048	198..>508	CDD:227381	84/338 (25%)
		C2H2 Zn finger	221..241	CDD:275368	5/19 (26%)
		C2H2 Zn finger	249..269	CDD:275368	6/19 (32%)
		C2H2 Zn finger	277..297	CDD:275368	6/19 (32%)
		C2H2 Zn finger	305..327	CDD:275368	6/21 (29%)
		C2H2 Zn finger	338..359	CDD:275368	7/20 (35%)
		C2H2 Zn finger	367..384	CDD:275368	5/16 (31%)
		C2H2 Zn finger	400..420	CDD:275368	2/19 (11%)
		C2H2 Zn finger	451..471	CDD:275368	5/19 (26%)
		C2H2 Zn finger	480..500	CDD:275368	5/19 (26%)
		C2H2 Zn finger	508..528	CDD:275368	7/19 (37%)
		SUF4-like	536..>586	CDD:411020	19/53 (36%)
		C2H2 Zn finger	537..558	CDD:411020	8/20 (40%)
		C2H2 Zn finger	537..557	CDD:275368	8/19 (42%)
		C2H2 Zn finger	565..586	CDD:411020	7/24 (29%)
		C2H2 Zn finger	565..582	CDD:275368	5/20 (25%)
Zfp472	NP_694703.2	KRAB	9..50	CDD:460171	2/8 (25%)
		COG5048	195..>492	CDD:227381	95/334 (28%)
		C2H2 Zn finger	199..219	CDD:275368	5/19 (26%)
		C2H2 Zn finger	227..247	CDD:275368	6/19 (32%)
		C2H2 Zn finger	255..275	CDD:275368	6/19 (32%)
		C2H2 Zn finger	283..303	CDD:275368	6/21 (29%)
		C2H2 Zn finger	311..331	CDD:275368	7/20 (35%)
		C2H2 Zn finger	339..359	CDD:275368	8/31 (26%)
		C2H2 Zn finger	367..387	CDD:275368	5/30 (17%)
		C2H2 Zn finger	395..415	CDD:275368	5/19 (26%)
		C2H2 Zn finger	423..443	CDD:275368	5/19 (26%)
		C2H2 Zn finger	451..471	CDD:275368	7/19 (37%)
		C2H2 Zn finger	479..499	CDD:275368	8/19 (42%)
		C2H2 Zn finger	507..527	CDD:275368	4/19 (21%)