Protein Alignment CG8301 and Zfp583

DIOPT Version :10

• Sequence 1: NP_649915.1
• Gene: CG8301 / 41160
• FlyBaseID: FBgn0037717
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: XP_030098197.1
• Gene: Zfp583 / 213011
• MGIID: 2682297
• Length: 608
• Species: Mus musculus
• Alignment Length: 525
• Identity: 138/525 - (26%)
• Similarity: 216/525 - (41%)
• Gaps: 94/525 - (17%)

  Fly    88 SHIYDKIDASSLEDD---------EIGQEDLEPAEEHQETETTKPTTTVSAETQPNNTASDPI-- 141
            ||....:|...|::|         .:|::::   ..||...|.|...  .:|.:..|.:...:
Mouse   147 SHFSSSLDCPDLKEDHENEDWFKNRLGRQEV---HSHQLFITHKEVP--ESEIRGCNPSCQAVHQ 206

  Fly   142 EIFVDAVDIDEAEEEEEEEEQQQQYDEEVEEPITDESAPPQLTISYACKFCLRPQENYQLQQLLL 206
            ...:|.......:|..::.|.|::                    ||..|......:..|:::.:|
Mouse   207 NAILDVPQCSSTKERIDQSEPQKR--------------------SYRKKSVEMKHKKVQVEKRIL 251

  Fly   207 EHINASHDPEQPYNCPECEARFQDAASRTVHLKSSHVEKQHACGVCGKKYGDRHNLRHHVEKYHS 271
            :             |.|||..|...:|.|:|.:....||.:||..|||.:....||..|...:..
Mouse   252 K-------------CSECEKVFNQTSSLTLHQRIHTGEKPYACVECGKAFSQSANLAQHKRIHTG 303

  Fly   272 ETDFECALCEKRFYTRKSLNYHMKWHNPDRQFKCRHSGCERLFISQRHLMCHEATHSGTSSRKSE 336
            |..:||..|.|.|.....|..|.:.|..::.::|:.  |::.|....||..|:..|:|   .:..
Mouse   304 EKPYECKECRKAFSQNAHLAQHQRVHTGEKPYQCKE--CKKAFSQIAHLTQHQRIHTG---ERPF 363

  Fly   337 HCGFCGKTFIHLKTLRWHIYRQHGGEKPYKCANCTEVFAS----YAEKRIHMLERHRENLTAIER 397
            .|..|||.|.:...|..| .|.|.|||||.|..|.:.|:.    ...:|||..||         .
Mouse   364 ECIECGKAFSNGSFLAQH-QRIHTGEKPYVCHVCGKAFSHRGYLIVHQRIHTGER---------P 418

  Fly   398 SECMLCRQPFSSEPDLIHHMSAEHLQRPGAPIIANNKRVLQQKRERQYSGLFQCGSCSQRFNMKS 462
            .||..||:.||....|..|......::|                       ::|..|.:.|:..:
Mouse   419 YECKECRKSFSQYAHLSQHQRVHTGEKP-----------------------YECKVCRKAFSQVA 460

  Fly   463 ALERHAAVHSEKDRPHACPHCSKRFKRAQDMKWHIKTHEKEKPNVCDVCGKAFALKYVLTQHRLS 527
            .|::|..||: .::|:.|..|.|.|..:..:..|.::|..|||.:|..|.|.|:....|.||:..
Mouse   461 YLDQHQRVHT-GEKPYECAECRKAFSNSSSLAQHQRSHTGEKPYICKECRKTFSQNAGLAQHQRI 524

  Fly   528 HEVLEKNFKCNVCGRAYLFEKSLRLHQRTHTGKTYYKCDLCQERFVTHIKLKTHMQKAHAASQPH 592
            | ..||.::||:||:|:.:..||.||||.|||:..|:|..|::.|.....| .|.:|.|......
Mouse   525 H-TGEKPYECNICGKAFSYSGSLTLHQRIHTGERPYECKDCRKSFRQRAHL-AHHEKVHTMESFL 587

  Fly   593 SADQP 597
            |...|
Mouse   588 SLSSP 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8301	NP_649915.1	zf-AD	3..88	CDD:462262	138/525 (26%)
		COG5048	198..>508	CDD:227381	85/313 (27%)
		C2H2 Zn finger	221..241	CDD:275368	8/19 (42%)
		C2H2 Zn finger	249..269	CDD:275368	7/19 (37%)
		C2H2 Zn finger	277..297	CDD:275368	6/19 (32%)
		C2H2 Zn finger	305..327	CDD:275368	6/21 (29%)
		C2H2 Zn finger	338..359	CDD:275368	8/20 (40%)
		C2H2 Zn finger	367..384	CDD:275368	5/20 (25%)
		C2H2 Zn finger	400..420	CDD:275368	7/19 (37%)
		C2H2 Zn finger	451..471	CDD:275368	5/19 (26%)
		C2H2 Zn finger	480..500	CDD:275368	5/19 (26%)
		C2H2 Zn finger	508..528	CDD:275368	7/19 (37%)
		SUF4-like	536..>586	CDD:411020	21/49 (43%)
		C2H2 Zn finger	537..558	CDD:411020	11/20 (55%)
		C2H2 Zn finger	537..557	CDD:275368	11/19 (58%)
		C2H2 Zn finger	565..586	CDD:411020	6/20 (30%)
		C2H2 Zn finger	565..582	CDD:275368	4/16 (25%)
Zfp583	XP_030098197.1	KRAB	45..106	CDD:214630
		COG5048	240..581	CDD:227381	116/394 (29%)
		C2H2 Zn finger	253..273	CDD:275368	8/19 (42%)
		C2H2 Zn finger	281..301	CDD:275368	7/19 (37%)
		C2H2 Zn finger	309..329	CDD:275368	6/19 (32%)
		C2H2 Zn finger	337..357	CDD:275368	6/21 (29%)
		C2H2 Zn finger	365..385	CDD:275368	8/20 (40%)
		C2H2 Zn finger	393..413	CDD:275368	4/19 (21%)
		C2H2 Zn finger	421..441	CDD:275368	7/19 (37%)
		C2H2 Zn finger	449..469	CDD:275368	5/19 (26%)
		C2H2 Zn finger	477..497	CDD:275368	5/19 (26%)
		C2H2 Zn finger	505..525	CDD:275368	7/19 (37%)
		C2H2 Zn finger	533..553	CDD:275368	11/19 (58%)
		C2H2 Zn finger	561..581	CDD:275368	6/20 (30%)