DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8301 and LOC102553962

DIOPT Version :9

Sequence 1:	NP_649915.1	Gene:	CG8301 / 41160	FlyBaseID:	FBgn0037717	Length:	607	Species:	Drosophila melanogaster
Sequence 2:	XP_006230432.1	Gene:	LOC102553962 / 102553962	RGDID:	7731019	Length:	460	Species:	Rattus norvegicus

Alignment Length:	495	Identity:	124/495 - (25%)
Similarity:	182/495 - (36%)	Gaps:	138/495 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 IGQEDLEPA-----EEHQETETTKPTTTVSAETQPNNTASDPIEIFVDAVDIDEAEEEEEEEEQQ 163
            :|....:||     ||  |||...|            .|.|| |:.:...::.....:||:..:.
  Rat    61 LGVRGAKPALICWVEE--ETELWGP------------RAQDP-ELAMCKTEVHSDCRQEEKRRKP 110

  Fly   164 QQYDEEVEEPITDESAPPQLTISYACKFCLRPQENYQLQQLLLEHINASHDPEQPYNCPECEARF 228
            ::..|.::...:.|:.|.:..:::|.     |..|..|         .|.||:|
  Rat   111 REETEAIQRTFSTEAGPKEPHLTFAA-----PSTNLDL---------LSKDPQQ----------- 150

  Fly   229 QDAASRTVHLKSSHVEKQHACGVCGKKYGDRHNLRHHVEKYHSETDFECALCEKRFYTRKSLNYH 293
            ....|.:|..:.....|:|.|.||||.:..|..|..|:..:..|..|:|..|.|.|....||:.|
  Rat   151 GPPTSGSVRARVLRANKRHGCHVCGKSFAQRPTLVEHLYTHTGEKPFQCPECNKCFGRASSLSMH 215

  Fly   294 MKWHNPDRQFKCRHSGCERLFISQRHLMCHEATHSGTSSRKSEHCGFCGKTFIHLKTLRWHIYRQ 358
            ...|..:|..:|  ..||:.| |||                              .||..|:| .
  Rat   216 RAIHRGERPHRC--PNCEKCF-SQR------------------------------STLVAHLY-T 246

  Fly   359 HGGEKPYKCANCTEVFASYAEKRIHMLERHRENLTAIERSECMLCRQPFSSEPDLIHHMSAEHLQ 423
            |.||:|:.|.:|.:.|.     |...|..||    ||.|.|
  Rat   247 HTGERPFCCPDCNKCFG-----RASSLSTHR----AIHRKE------------------------ 278

  Fly   424 RPGAPIIANNKRVLQQKRERQYSGLFQCGSCSQRFNMKSALERHAAVHSEKDRPHACPHCSKRFK 488
            ||                       .:|..|.:.|..:|||..|..||: .::|:.|..|.:||.
  Rat   279 RP-----------------------HRCPYCERTFTQRSALTSHLRVHT-GEKPYCCADCGRRFS 319

  Fly   489 RAQDMKWHIK-THEKEKPNVCDVCGKAFALKYVLTQHRLSHEVLEKNFKCNVCGRAYLFEKSLRL 552
            |:..:..|.: .|....|..|.|||:|||....|.:|...| ..||.:.|..|||.:.....:..
  Rat   320 RSSGLHEHQRVVHSGMTPFSCTVCGRAFADSKYLRRHMRIH-TGEKPYSCPDCGRCFRQGSEIAA 383

  Fly   553 HQRTHTGKTYYKCDLCQERFVTHIKLKTHMQKAHAASQPH 592
            |:|||||:..|.|..|...|.|...:.:|.......::.|
  Rat   384 HRRTHTGERPYPCPQCGRGFRTKSAMTSHQWVHRPGAKGH 423

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8301	NP_649915.1	zf-AD	3..87	CDD:285071
		COG5048	198..>508	CDD:227381	75/310 (24%)
		C2H2 Zn finger	221..241	CDD:275368	2/19 (11%)
		C2H2 Zn finger	249..269	CDD:275368	8/19 (42%)
		C2H2 Zn finger	277..297	CDD:275368	7/19 (37%)
		C2H2 Zn finger	305..327	CDD:275368	7/21 (33%)
		C2H2 Zn finger	338..359	CDD:275368	4/20 (20%)
		C2H2 Zn finger	367..384	CDD:275368	4/16 (25%)
		C2H2 Zn finger	400..420	CDD:275368	0/19 (0%)
		C2H2 Zn finger	451..471	CDD:275368	7/19 (37%)
		C2H2 Zn finger	480..500	CDD:275368	6/20 (30%)
		C2H2 Zn finger	508..528	CDD:275368	9/19 (47%)
		C2H2 Zn finger	537..557	CDD:275368	6/19 (32%)
		C2H2 Zn finger	565..582	CDD:275368	4/16 (25%)
LOC102553962	XP_006230432.1	KRAB	22..81	CDD:214630	8/21 (38%)
		KRAB	22..61	CDD:279668	124/495 (25%)
		COG5048	<171..385	CDD:227381	81/305 (27%)
		C2H2 Zn finger	171..191	CDD:275368	8/19 (42%)
		zf-H2C2_2	184..208	CDD:290200	8/23 (35%)
		C2H2 Zn finger	199..219	CDD:275368	7/19 (37%)
		zf-H2C2_2	211..236	CDD:290200	9/27 (33%)
		C2H2 Zn finger	227..247	CDD:275368	11/53 (21%)
		zf-H2C2_2	240..264	CDD:290200	10/29 (34%)
		C2H2 Zn finger	255..275	CDD:275368	8/28 (29%)
		zf-H2C2_2	267..292	CDD:290200	12/75 (16%)
		C2H2 Zn finger	283..303	CDD:275368	7/19 (37%)
		zf-H2C2_2	295..320	CDD:290200	10/25 (40%)
		C2H2 Zn finger	311..330	CDD:275368	6/18 (33%)
		zf-C2H2	338..360	CDD:278523	9/21 (43%)
		C2H2 Zn finger	340..360	CDD:275368	9/19 (47%)
		zf-H2C2_2	352..377	CDD:290200	9/25 (36%)
		C2H2 Zn finger	368..388	CDD:275368	6/19 (32%)
		zf-H2C2_2	384..405	CDD:290200	10/20 (50%)
		C2H2 Zn finger	396..416	CDD:275368	5/19 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24377
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100