DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8301 and zscan2

DIOPT Version :9

Sequence 1:	NP_649915.1	Gene:	CG8301 / 41160	FlyBaseID:	FBgn0037717	Length:	607	Species:	Drosophila melanogaster
Sequence 2:	XP_002943732.2	Gene:	zscan2 / 100486661	XenbaseID:	XB-GENE-6033591	Length:	491	Species:	Xenopus tropicalis

Alignment Length:	440	Identity:	119/440 - (27%)
Similarity:	174/440 - (39%)	Gaps:	69/440 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 PTTTVSAETQPNNTASDPIEIFV--DAVDIDEAEEEEEEEEQQQQYDEEVEEPITDESAPPQLTI 185
            |.:|:||.:...:.:|...:::.  |........|....|..:|......:...|:.||..|...
Frog   111 PWSTLSARSDVPSASSFSTDLYPQRDPFTYIMPPESAANETSEQHLTAGSQTLCTNRSAKSQKKT 175

  Fly   186 SYACK--FCLRPQENYQLQQLLLEHINASHDPEQPYNCPECEARFQDAASRTVHLKSSHVEKQHA 248
            |...|  .|....:.:..:.||::| :.:|..|:|:.|.||...|...:....|.|....||..|
Frog   176 STKVKPFLCTTCGKRFSQKSLLIQH-HRNHTGERPFPCIECGKSFTSCSLLIRHHKIHTGEKPFA 239

  Fly   249 CGVCGKKYGDRHNLRHHVEKYHSETDFECALCEKRFYTRKSLNYHMKWHNPDRQFKCRHSGCERL 313
            |..|||::.:...|..|...:..|..:.|..|.|.|.....|..|.:.|..:|.:.|  |.|.:.
Frog   240 CSDCGKRFSESSQLVRHQRTHTGERPYTCIECGKSFSESSKLVIHQRTHTGERPYSC--SDCGKS 302

  Fly   314 FISQRHLMCHEATHSGTSSRKSEHCGFCGKTFIHLKTLRWHIYRQHGGEKPYKCANCTEVFASYA 378
            |..:.||:.|:.||:|   .:...|..|||:|.....|..| .|.|.|||||.||
Frog   303 FSVRSHLITHKRTHTG---ERPYTCNDCGKSFSESSKLVMH-QRIHTGEKPYTCA---------- 353

  Fly   379 EKRIHMLERHRENLTAIERSECMLCRQPFSSEPDLIHHMSAEHLQRPGAPIIANNKRVLQQKRER 443
                                   .|.:.||....|:.|......::|
Frog   354 -----------------------ACGKSFSQRSVLVTHQRIHTGEKP------------------ 377

  Fly   444 QYSGLFQCGSCSQRFNMKSALERHAAVHSEKDRPHACPHCSKRFKRAQDMKWHIKTHEKEKPNVC 508
                 :.|..|.:.|..|...:||...|| .::|..|..|.|.|.|..|...|.:||..|||..|
Frog   378 -----YTCPECGKSFIDKVGCDRHRVTHS-NEKPFQCLICGKNFSRNSDYNKHQRTHTGEKPYSC 436

  Fly   509 DVCGKAFALKYVLTQHRLSHEVLEKNFKCNVCGRAYLFEKSLRLHQRTHT 558
            ..|||.|:..|.|.:|:..| ..||.:.|..|||::.:...|..|||:|:
Frog   437 LECGKKFSWSYQLVRHQRVH-TGEKPYTCIECGRSFCWSYQLVTHQRSHS 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8301	NP_649915.1	zf-AD	3..87	CDD:285071
		COG5048	198..>508	CDD:227381	83/309 (27%)
		C2H2 Zn finger	221..241	CDD:275368	6/19 (32%)
		C2H2 Zn finger	249..269	CDD:275368	6/19 (32%)
		C2H2 Zn finger	277..297	CDD:275368	6/19 (32%)
		C2H2 Zn finger	305..327	CDD:275368	7/21 (33%)
		C2H2 Zn finger	338..359	CDD:275368	8/20 (40%)
		C2H2 Zn finger	367..384	CDD:275368	2/16 (13%)
		C2H2 Zn finger	400..420	CDD:275368	5/19 (26%)
		C2H2 Zn finger	451..471	CDD:275368	6/19 (32%)
		C2H2 Zn finger	480..500	CDD:275368	7/19 (37%)
		C2H2 Zn finger	508..528	CDD:275368	8/19 (42%)
		C2H2 Zn finger	537..557	CDD:275368	8/19 (42%)
		C2H2 Zn finger	565..582	CDD:275368
zscan2	XP_002943732.2	COG5048	<68..314	CDD:227381	53/205 (26%)
		C2H2 Zn finger	184..204	CDD:275368	4/20 (20%)
		zf-H2C2_2	197..221	CDD:290200	9/24 (38%)
		COG5048	208..>471	CDD:227381	93/326 (29%)
		C2H2 Zn finger	212..232	CDD:275368	6/19 (32%)
		zf-H2C2_2	225..248	CDD:290200	9/22 (41%)
		C2H2 Zn finger	240..260	CDD:275368	6/19 (32%)
		zf-H2C2_2	253..276	CDD:290200	6/22 (27%)
		C2H2 Zn finger	268..288	CDD:275368	6/19 (32%)
		zf-H2C2_2	281..304	CDD:290200	7/24 (29%)
		C2H2 Zn finger	296..316	CDD:275368	7/21 (33%)
		zf-H2C2_2	308..332	CDD:290200	10/26 (38%)
		C2H2 Zn finger	324..344	CDD:275368	8/20 (40%)
		zf-H2C2_2	337..361	CDD:290200	13/57 (23%)
		C2H2 Zn finger	352..372	CDD:275368	7/52 (13%)
		zf-H2C2_2	365..387	CDD:290200	5/44 (11%)
		C2H2 Zn finger	380..400	CDD:275368	6/19 (32%)
		zf-C2H2	406..428	CDD:278523	7/21 (33%)
		C2H2 Zn finger	408..428	CDD:275368	7/19 (37%)
		zf-H2C2_2	420..444	CDD:290200	11/23 (48%)
		C2H2 Zn finger	436..456	CDD:275368	8/19 (42%)
		zf-H2C2_2	449..471	CDD:290200	9/22 (41%)
		C2H2 Zn finger	464..484	CDD:275368	8/19 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24377
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100