Protein Alignment Son and GPATCH2

DIOPT Version :9

• Sequence 1: NP_001262426.1
• Gene: Son / 41159
• FlyBaseID: FBgn0037716
• Length: 874
• Species: Drosophila melanogaster
• Sequence 2: XP_011507991.1
• Gene: GPATCH2 / 55105
• HGNCID: 25499
• Length: 551
• Species: Homo sapiens
• Alignment Length: 598
• Identity: 114/598 - (19%)
• Similarity: 198/598 - (33%)
• Gaps: 206/598 - (34%)

  Fly   230 KEKSESRKRSAVEPSSHS---------EKRERHEREK-----HRDWE--------REREREKEHE 272
            :|.||..:....|...||         :.|:|..|::     |..||        .:...|:..:
Human    37 EESSEQARGGFAETGDHSRSISCPLKRQARKRRGRKRRSYNVHHPWETGHCLSEGSDSSLEEPSK 101

  Fly   273 RERVRSNNSFYNGQREADRLKGSESASTKSRQEQDLSDISLSDEESYL--REKASN------GRR 329
            ..|...||:                       ::|.||   ||::..:  |..:||      |:|
Human   102 DYRENHNNN-----------------------KKDHSD---SDDQMLVAKRRPSSNLNNNVRGKR 140

  Fly   330 RA-HNSFY--DEKEELSVSPKRNVRE---------SNTRRNRKSRSRSRDLGIDKKRLLEI---- 378
            .. |.|.:  |.....::..:|.|:.         ||.|...:.....||..:|..|..:.
Human   141 PLWHESDFAVDNVGNRTLRRRRKVKRMAVDLPQDISNKRTMTQPPEGCRDQDMDSDRAYQYQEFT 205

  Fly   379 ---ARRNAINMFKQGTMPGVANMTAEVKDK-VLVKMRYGGRTIQDLTDFC--KKISNGDGLSDLS 437
               .::..:.:.:||         .:::|: |:::.....:|.:|..: |  :|:|:     :|.
Human   206 KNKVKKRKLKIIRQG---------PKIQDEGVVLESEETNQTNKDKME-CEEQKVSD-----ELM 255

  Fly   438 SEEESDVDKNGNAKVFHHP------------FQLKEREPIVMHIRNSTALVP-----APPRLDEQ 485
            ||.:|....:.:|.:|.:.            |..||.....    ..|.:||     .|..||:.
Human   256 SESDSSSLSSTDAGLFTNDEGRQGDDEQSDWFYEKESGGAC----GITGVVPWWEKEDPTELDKN 316

  Fly   486 T------KAITMQFPVSSGQTHRNNEVWVPVDPKDSLVPLPSLPPAKQATNMFKETPKNVFAKSI 544
            .      ..:|..||:.|..:.|..:.                    :.:.:...:.||:
Human   317 VPDPVFESILTGSFPLMSHPSRRGFQA--------------------RLSRLHGMSSKNI----- 356

  Fly   545 PLQEQQEPAFKPLGGAVVVPPLAATQLPTVPQSVPPTVPKEFAPPAVPFVPEVPIPSTSPVTPMQ 609
                      |..||              .|.|:                  ||||  .||...:
Human   357 ----------KKSGG--------------TPTSM------------------VPIP--GPVGNKR 377

  Fly   610 SASIFPDVTPPSMDVSSIITQRLSAIRRLQENPADSEALK--MMYTAQRNMSSWANS-------- 664
            .....||........|..........:.|::|.|:....|  .:.||.|..|....|
Human   378 MVHFSPDSHHHDHWFSPGARTEHDQHQLLRDNRAERGHKKNCSVRTASRQTSMHLGSLCTGDIKR 442

  Fly   665 ----KHLPGQFTGSTGAQVM-KAHELNSGPQLWVRKDQM-TSTKPV-TGGMGMALLQKMGWKPGE 722
                ..|||..|..|.:.:: :.|.::...|::.:...: .:.:|: ...:|..:||.|||.||.
Human   443 RRKAAPLPGPTTAGTCSHILDETHVISLAIQIFHKAGFVGENAQPILENNIGNRMLQNMGWTPGS 507

  Fly   723 GLGRCKTGSLQPL 735
            ||||...|..:|:
Human   508 GLGRDGKGISEPI 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Son	NP_001262426.1	PHA03247	<455..627	CDD:223021	30/194 (15%)
		G-patch	705..747	CDD:396249	14/31 (45%)
		DSRM_SON-like	798..872	CDD:380699
GPATCH2	XP_011507991.1	G-patch	491..534	CDD:279867	14/30 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4438
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.030