Protein Alignment Son and Son

DIOPT Version :10

• Sequence 1: NP_649914.1
• Gene: Son / 41159
• FlyBaseID: FBgn0037716
• Length: 874
• Species: Drosophila melanogaster
• Sequence 2: XP_061518493.1
• Gene: Son / 1275255
• VectorBaseID: AGAMI1_009194
• Length: 959
• Species: Anopheles gambiae
• Alignment Length: 1043
• Identity: 378/1043 - (36%)
• Similarity: 519/1043 - (49%)
• Gaps: 258/1043 - (24%)

  Fly     1 MTENTEKGASVETPQVAGSQTNPPVQEPLALTKIPPIKVKSER-------PDAEVEAKLRAMNAK 58
            |:...||    :..|..|.:|    |:...|.    ||:|.|:       ..:|...|| :::..
Mosquito     1 MSATNEK----QDKQQKGDKT----QDIFPLN----IKIKQEKTTSYEDSSKSETVDKL-SIDVN 52

  Fly    59 IKAEMVTLMRRSNSNELGNNDESGESESSASADDKKNIKPVKSSNEILAELFGVFNAAPPEELLD 123
            :|....|.:..|:||...|..|.|    |.:.|.|..::|:|||||||.|||.||||||||.:.|
Mosquito    53 LKNIFSTTITSSSSNSNSNTAEKG----SDNVDVKPALEPLKSSNEILTELFRVFNAAPPEIIED 113

  Fly   124 D--NLFKKKKKVKKEKKDKKAKKKKTTKSDGECSDSEA---------EGKHKHKRKKHKHKDIRV 177
            |  :..:::||.||.|..||:||||.::|:|..:|.|.         :|:.:.||||.|
Mosquito   114 DSNDAVEQEKKKKKHKHKKKSKKKKGSESEGGGTDEEPIVPESVVVDDGEKRVKRKKIK------ 172

  Fly   178 KDKEKDRDRDKSKEKDRDR-----VTDKSKEKDRDRDR------DRDKSKDKFTAAQAPSE---- 227
              |||||||...:.|.|..     ||.|.:..| |.||      :....::|.|.|:.|.|
Mosquito   173 --KEKDRDRKHKRSKLRTSGETLLVTVKQEPVD-DTDRPAKPLVEAKWKEEKKTKAEKPEETKPP 234

  Fly   228 -KEKEKSESRKRSA----VEPSSHSEKRERHEREKHRDWEREREREKEHERERVRSNNSFYNGQR 287
             |.|.:.:|.|.||    :..||.....|||:.|:|||.||::...|              :.:.
Mosquito   235 LKGKIQIKSLKDSAIFREIATSSAQPAVERHQHERHRDHERDKPSHK--------------SSRS 285

  Fly   288 EADRLKGSESASTKSRQEQDLSDISLSDEESYLREKASNGR-----RRAHNSFY---DEKEELSV 344
            |..:.|.||            :|.|||::|    |....||     ::.:||||   :|:::...
Mosquito   286 ELRKRKTSE------------TDFSLSEDE----ENRKGGRYYDFYQKKYNSFYAGFEEEDDRKK 334

  Fly   345 SPKRNVR--ESNTRRNR-----KSRSRSRDLG-----------IDKKRLLEIARRNAINMFKQGT 391
            ..::..|  |...||:|     |||||||...           |||::||||||:|||:|.|:||
Mosquito   335 HDRKRHRYSEDRVRRHRSNTFSKSRSRSRSRSRSRSRSRSKEQIDKQKLLEIARKNAISMLKKGT 399

  Fly   392 MPGVANMTAEVKDKVLVKMRYGGRTIQDLTDFCKKISNGDGLSDLS--SEEESDVDKNGNAKVFH 454
            :||..|:..|.|.|::.||...|:||::||.||||||:.|..:|||  |.:|||.|.:|.:|.||
Mosquito   400 LPGAQNLDGESKAKLISKMHASGKTIEELTAFCKKISHKDNANDLSSVSSDESDHDADGASKAFH 464

  Fly   455 HPFQLKEREPIVMHIRNSTALVPAPPRLDEQTKAITMQFPVSSGQTHRNNEV-WVPVDPKDSLVP 518
            |||||||..||||:|||:|.:   .|:..|:.||:.||||||||..||:.|. ||||:||.:
Mosquito   465 HPFQLKEAAPIVMNIRNATTI---QPKSAEEKKALLMQFPVSSGVHHRSTETEWVPVEPKKT--- 523

  Fly   519 LPSLPPAKQATNMFKET-------------PKNVFAKSIPLQEQQEPAFKPL-----------GG 559
            :|:..|..:.......|             |.:.|   :|.|.::.||  ||           ..
Mosquito   524 VPTTKPGTETGGSGSGTFFGNKSKLKTILPPSSTF---VPQQSKEFPA--PLQPPPAPPTIVPAP 583

  Fly   560 AVVVPPLAATQL------PTVPQSVP--PTVP---KEFAPPA------------VP--------- 592
            |..:|||..:.:      |.||...|  .|||   ..:.||.            ||
Mosquito   584 APAIPPLMQSHVGHMPVAPIVPSPYPSNETVPPYQSSYHPPVNQHQQMPQATHPVPSHAPSFNSM 648

  Fly   593 FVPE----------VPIPSTSPV--------TPMQSASIFPDVTP-------------------- 619
            ..||          :|.|:.:|:        .|.|...:||...|
Mosquito   649 MTPEPSMGLPVDTSIPPPNMNPIGANPQHQDPPQQPRPLFPPAGPGGPGSSHPHAPHQGPGPDNV 713

  Fly   620 -------PSMDVSSIITQRLSAIRRLQENPADSEALKMMYTAQRNMSSWANSKHLPGQFTGSTGA 677
                   |.:|||.|::|||:|:|||||||.||:|.:|:|..|::||:||:||.:||||.||||.
Mosquito   714 FNTQPDAPIIDVSQIVSQRLNAMRRLQENPTDSDARQMLYNTQKDMSTWASSKAMPGQFLGSTGV 778

  Fly   678 QVMKAHELNSGPQLWVRKDQMTSTKPVTGGMGMALLQKMGWKPGEGLGRCKTGSLQPLLLDVKLD 742
            ..:...||..|.|.|..:|.|..:.||||||||.|||||||:||||||:.|.|||||||||||||
Mosquito   779 NCLSQRELAEGYQPWATRDMMKQSAPVTGGMGMHLLQKMGWQPGEGLGKEKNGSLQPLLLDVKLD 843

  Fly   743 KRGLVSRDDL----RPPQMRAPAAQRRNKNMAGPIGAGPCPAVQGAGPGPLASTPLVTQDKHPVC 803
            ||||...|:.    :|..|:||..:|..::.                   ..:..:.|..||||.
Mosquito   844 KRGLGEGDNKQRSHQPYPMQAPFGRRDARSR-------------------FVNLKINTDGKHPVS 889

  Fly   804 VLNELTSKNKWMPPQYKLRQDIGPAHNRSFLFSVEINGQTFTPDRGSNNKKEAKLNAAALCLRSL 868
            :|.|..:|:||..|.|:|..:.||.|.::|:|.|.:||..:.|...:|.|||||..||..||:.|
Mosquito   890 ILCEYATKHKWNAPMYELVHESGPGHAKNFIFKVLVNGLEYQPAIANNTKKEAKATAAKFCLQQL 954

  Fly   869 GIL 871
            |::
Mosquito   955 GVM 957

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Son	NP_649914.1	PHA03247	<455..627	CDD:223021	76/273 (28%)
		G-patch	705..747	CDD:396249	36/41 (88%)
		DSRM_SON-like	798..872	CDD:380699	33/74 (45%)
Son	XP_061518493.1	None