Protein Alignment Son and son

DIOPT Version :10

• Sequence 1: NP_649914.1
• Gene: Son / 41159
• FlyBaseID: FBgn0037716
• Length: 874
• Species: Drosophila melanogaster
• Sequence 2: XP_012813456.2
• Gene: son / 100036715
• XenbaseID: XB-GENE-6037418
• Length: 5561
• Species: Xenopus tropicalis
• Alignment Length: 1081
• Identity: 273/1081 - (25%)
• Similarity: 408/1081 - (37%)
• Gaps: 371/1081 - (34%)

  Fly     5 TEKGASVETPQVAGSQTNPPVQEPLALTKIPPIKVKSERPDAEVE-AKLRAMNAKIK-------- 60
            ||..:|.|: ||:.......:....|.:.:|.:|..:..|:|..: ::.|::..:.|
 Frog  4621 TELSSSTES-QVSEVTMAGKLIATSAQSAVPALKESALLPEATCKRSRSRSVTKRTKSRSKSISR 4684

  Fly    61 -----AEMVTLMRRSNSNELGNNDESGESESSASADDKKNI-KPVKSSNEILAELFGVFNAAPPE 119
                 ::.||.|:||.|..........:|.:|......|:: |..:|.::.:.:
 Frog  4685 SRDSRSKSVTRMKRSRSKSGTRKRSRSKSATSWKRSRSKSVAKRQRSQSKTVMQ----------- 4738

  Fly   120 ELLDDNLFKKKKKVKKEKKDKK-------------AKKKKTTKSD--GECSDSEAEGKHKHKRKK 169
                 ....:.|.|.:..:.|.             .:|:..:|||  ...|.|.:.|:.:..|.:
 Frog  4739 -----GKRSRSKSVTRRSRSKSYLQRRRSWSKSTTRRKRSQSKSDTGKRRSRSRSVGRKRRSRSR 4798

  Fly   170 HKHKDIRVKDKEKDRDR-DKSKEKDRDRVTDKSKEKDRDRDRDRDKSKDKFTAAQAPSEKEKEKS 233
            ...:..|.:.|...|.| .:||...|.| ..:||...| ::|.|.||..:...:::||...:::|
 Frog  4799 SVGRKRRSRSKSPVRKRHSRSKSAGRKR-RSRSKSAGR-KNRSRSKSVGRKRRSRSPSTSRRKRS 4861

  Fly   234 ES--RKRSAVEPSSHSEKRERHEREKHRDWER--------EREREKEHERERVRSNNSFYNGQRE 288
            .|  |:||    ||.|..|.|..|.......|        .|.|.:.....|.|.:.|...|.|.
 Frog  4862 RSVRRRRS----SSASVARRRRSRSTSVARRRRSRSTSVVRRRRSRSSSVARRRRSRSVSAGPRR 4922

  Fly   289 AD----------------------------------------------------RLKGSESASTK 301
            :.                                                    |..||.|.:.|
 Frog  4923 SSRSVSVPRKRRSCSPSVSRRRRTRSPSVSRRRRSRTPSVSRRRRSRSPSVGRRRRSGSTSVTRK 4987

  Fly   302 SRQEQDL-------------------------------------------SDISLSDE------E 317
            .|.....                                           |.:|.||.      .
 Frog  4988 GRSRSGSLAHRRRSRSASEACTKRSRSVSATRKKRSVSKSLTPKSPTYKPSAVSRSDRSRSHSAS 5052

  Fly   318 SYLRE-------------KASNGRRRAHNSFYDEKEELSVSPKRNVRESNTRRN----------- 358
            :.||:             |.|..|||..||    |:..:|..:|..|....|:.
 Frog  5053 NVLRKRKTRSRSSSRDKNKLSEKRRRRSNS----KDHYNVKSRRRSRTPPRRKKSRSPIKRMSPV 5113

  Fly   359 -------------------RKSRSRSRD------------LGIDKKRLLEIARRNAINM-FKQGT 391
                               |:.||||||            ..:||.:|||||:.||..| .|.|.
 Frog  5114 RRRRSRSAIRRKSFSRSPVRRKRSRSRDKSLDSSRSPKRLTDLDKAQLLEIAKANAAAMCAKAGV 5178

  Fly   392 ------MPGVANMTAEVKDKVLVKMRYGGRTIQDLTDFCKKI--SNGDGLSDLSSEEESDVDKNG 448
                  .|.:|.:| .|::|  :.:|..|.|||:||:.||:|  |..|.:. ::...:||.::..
 Frog  5179 PLPPSLKPVIAPVT-PVEEK--ITLRSYGVTIQELTEKCKQIAQSKEDDVI-VNKPHDSDEEEEE 5239

  Fly   449 NAKVFHHPFQLKEREPIVMHIRNSTALVPAPPRLDEQTKAITMQFPVSSGQTHRNNEV------W 507
            ....::|||::.|.:||...:.| .::.|||    :....:|.:||||||..||..|.      |
 Frog  5240 ERPFYNHPFKVSEHKPISFSLLN-PSVKPAP----KNQVTLTKEFPVSSGSQHRKKEADKVYGEW 5299

  Fly   508 VPVDPKDSLVPLPSLPPAKQATNMFKETPKNVFAKSIPLQEQQEPAFKPLGGAVVVPPLAATQLP 572
            ||||.|.                  :|:..:||.
 Frog  5300 VPVDKKS------------------EESKDDVFT------------------------------- 5315

  Fly   573 TVPQSVPPTVPKEFAPPAVPFVPEVPIPSTSPVTPMQSASIFPDVTPPSMDVSSIITQRLSAIRR 637
                                        :|.|..|              :|::|.:.:|..|..|
 Frog  5316 ----------------------------NTGPSQP--------------VDITSAMNERALAQTR 5338

  Fly   638 LQENPADSEALKMMYTAQRNMSSWANSKHLPGQFTGSTGAQVMKAHEL-NSGPQLWVRKDQMTST 701
            |..||.|.|||.|:..||..:.:||.|..|||||||||||||:.|.|: |||||.|::|||....
 Frog  5339 LTGNPFDMEALIMLNRAQEQIDAWAQSTSLPGQFTGSTGAQVLSADEISNSGPQAWLKKDQFLKA 5403

  Fly   702 KPVTGGMGMALLQKMGWKPGEGLGRCKTGSLQPLLLDVKLDKRGLVSRDDLRPPQMRAPAAQRRN 766
            .|||||.|..|::|||||.|:||||...|::.|:|:|.|.|::|||:..:....::..|..
 Frog  5404 APVTGGRGALLMRKMGWKEGKGLGRHNEGNVDPILIDFKTDRKGLVADGEKASNKLALPMM---- 5464

  Fly   767 KNMAGPIGAGPCPAVQGAGPGPLASTPLVTQDKHPVCVLNELTSKNKWMPPQYKLRQDIGPAHNR 831
            |:::|                           |||:..|.||.:|.||.||::.|..|.||.|.:
 Frog  5465 KDLSG---------------------------KHPISALMELCNKKKWSPPEFVLVDDTGPEHRK 5502

  Fly   832 SFLFSVEINGQTFTPDRGSNNKKEAKLNAAALCLRSLGILP 872
            .|||.|.:||..:.|::.|.|||.||..|||..|::||.||
 Frog  5503 RFLFRVTVNGGVYQPNQPSVNKKLAKATAAAAALQALGALP 5543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Son	NP_649914.1	PHA03247	<455..627	CDD:223021	33/177 (19%)
		G-patch	705..747	CDD:396249	22/41 (54%)
		DSRM_SON-like	798..872	CDD:380699	35/73 (48%)
son	XP_012813456.2	RSRP	2193..>2346	CDD:293674
		RSRP	4691..>4777	CDD:293674	15/101 (15%)
		G-patch	5407..5451	CDD:396249	24/43 (56%)
		DSRM_SF	5469..>5523	CDD:444671	25/80 (31%)