Protein Alignment Kap-alpha3 and kpna7

DIOPT Version :10

• Sequence 1: NP_731377.1
• Gene: Kap-alpha3 / 41158
• FlyBaseID: FBgn0027338
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_998235.1
• Gene: kpna7 / 406343
• ZFINID: ZDB-GENE-040426-2023
• Length: 520
• Species: Danio rerio
• Alignment Length: 508
• Identity: 221/508 - (43%)
• Similarity: 331/508 - (65%)
• Gaps: 15/508 - (2%)

  Fly     3 SMEQNRLQNFKNKGKDQDEMRRRRNEVTVELRKNKREETILKRRNVPNL--------DSNTDEEE 59
            ::...|:..||||||:..::|.||....||.||.:|.|.|:||||:.:|        :.|||.|:
Zfish     5 NLSDKRMSKFKNKGKEPTKLRDRRVAECVEFRKAQRVEGIMKRRNITSLGDEEPLSPEFNTDNEQ 69

  Fly    60 QLSSSIDLKKLAKAAADATKPEQQLAAVQAARKLLSSDKNPPINDLIQSDILPILVECLKQHNHT 124
            .:.::|: :.:|....|.  ||:|....||||||||.::|||:.::|::.:|...||.|.:::..
Zfish    70 VICTTIE-EIVANVNTDC--PEKQRNGCQAARKLLSRERNPPLKEIIEAGLLTRFVEFLGRNDDP 131

  Fly   125 MLQFEAAWALTNIASGTSAQTNEVVAAGAVPLFLQLLNSPAPNVCEQAVWALGNIIGDGPLLRDF 189
            .|||||||:|||:|||||..|.:||..||||.|:.||.||..|:.||||||||||.|||...||.
Zfish   132 TLQFEAAWSLTNVASGTSWHTQQVVEHGAVPAFIALLASPMLNISEQAVWALGNIAGDGSSYRDA 196

  Fly   190 VIKHGVVQPLLSFIKPDIPITFLRNVTWVIVNLCRNKDPAPPTATIHEILPALNVLIHHTDTNIL 254
            :|..||:..||:.:.||.|:.:|||:||.:.||||||:|.|..:.:.::||::..|:||:|.:||
Zfish   197 LIDCGVIPALLARLTPDAPVGYLRNLTWTLSNLCRNKNPFPRFSAVQQMLPSIIQLLHHSDKSIL 261

  Fly   255 VDTVWAISYLTDGGNDQIQMVIESGVVPKLIPLLGNSEVKVQTAALRAVGNIVTGSDEQTQVVLN 319
            .|..|||||||||.|::|.::|::|::.:|:.|||..|:.|.|.|||::.|||:|||.|||..::
Zfish   262 SDACWAISYLTDGPNERIDVIIKAGILTRLVELLGFEELAVVTPALRSIENIVSGSDLQTQAAID 326

  Fly   320 YDALSYFPGLLSHPKEKIRKEAVWFLSNITAGNQSQVQAVINVGLLPKIIENLSKGEFQTQKEAA 384
            ...||..|.|:.|.|..::|||.|.:|||.||...|:|.:|..||...:::.|..|:|:||:||.
Zfish   327 AGVLSALPKLMRHQKSSVQKEAAWAVSNIAAGPCQQIQQLITCGLSAPLVDLLRNGDFKTQREAV 391

  Fly   385 WAISNLTISGNREQVFTLIKEGVIPPFCDLLSCQDTQVINVVLDGLNNMLKVAD--SHVEAVANC 447
            ||::|.|..|..|||..|:|.|.:....:||..:||:.:.|:||.::|:...|:  ..|:.:...
Zfish   392 WAVTNYTSGGTVEQVVHLVKCGALEAILNLLQVKDTKTVLVILDAISNIFLAAEKLGEVDKLCLL 456

  Fly   448 IEECEGLAKIERLQSHENVEIYKLAYEIIDQYFTDEGEQTNMAPTSDGAQYNF 500
            :||..||.:||..|:|||..:|:.|..:|::||:::||  :...|::....||
Zfish   457 VEEVGGLDRIEFFQNHENNAVYRAAQALIEKYFSEDGE--DQCLTTEATDANF 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kap-alpha3	NP_731377.1	SRP1	8..500	CDD:227396	219/501 (44%)
		armadillo repeat	104..137	CDD:293788	14/32 (44%)
		armadillo repeat	145..181	CDD:293788	23/35 (66%)
		armadillo repeat	187..222	CDD:293788	15/34 (44%)
		armadillo repeat	239..264	CDD:293788	13/24 (54%)
		armadillo repeat	272..308	CDD:293788	15/35 (43%)
		armadillo repeat	314..348	CDD:293788	13/33 (39%)
		armadillo repeat	356..390	CDD:293788	13/33 (39%)
		armadillo repeat	399..433	CDD:293788	11/33 (33%)
kpna7	NP_998235.1	SRP1	1..520	CDD:227396	221/508 (44%)
		armadillo repeat	112..144	CDD:293788	14/31 (45%)
		armadillo repeat	152..188	CDD:293788	23/35 (66%)
		armadillo repeat	194..229	CDD:293788	15/34 (44%)
		armadillo repeat	246..271	CDD:293788	13/24 (54%)
		armadillo repeat	279..315	CDD:293788	15/35 (43%)
		armadillo repeat	321..355	CDD:293788	13/33 (39%)
		armadillo repeat	363..399	CDD:293788	14/35 (40%)
		armadillo repeat	406..440	CDD:293788	11/33 (33%)