Protein Alignment Kap-alpha3 and KPNA7

DIOPT Version :9

• Sequence 1: NP_001163572.1
• Gene: Kap-alpha3 / 41158
• FlyBaseID: FBgn0027338
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: XP_016867697.1
• Gene: KPNA7 / 402569
• HGNCID: 21839
• Length: 548
• Species: Homo sapiens
• Alignment Length: 489
• Identity: 215/489 - (43%)
• Similarity: 314/489 - (64%)
• Gaps: 9/489 - (1%)

  Fly     6 QNRLQNFKNKGKDQDEMRRRRNEVTVELRKNKREETILKRRNVPNLDSNTDEEEQ---LSSSIDL 67
            :.|.:.||.:|||....|::|..|::||||.|::|..|||||:.:...:|..|:.   ::.|:.|
Human    35 EERRRKFKYRGKDVSLRRQQRMAVSLELRKAKKDEQTLKRRNITSFCPDTPSEKTAKGVAVSLTL 99

  Fly    68 KKLAKAAADATKPEQQLAAVQAARKLLSSDKNPPINDLIQSDILPILVECLKQHNHTMLQFEAAW 132
            .::.| ..:::.|.....|.|.|||:||.:||||:..:|::.::|.:||.||...:..|||||||
Human   100 GEIIK-GVNSSDPVLCFQATQTARKMLSQEKNPPLKLVIEAGLIPRMVEFLKSSLYPCLQFEAAW 163

  Fly   133 ALTNIASGTSAQTNEVVAAGAVPLFLQLLNSPAPNVCEQAVWALGNIIGDGPLLRDFVIKHGVVQ 197
            ||||||||||.||..||..||:...::||:|....||||||||||||.||||..||.||....:.
Human   164 ALTNIASGTSEQTRAVVEGGAIQPLIELLSSSNVAVCEQAVWALGNIAGDGPEFRDNVITSNAIP 228

  Fly   198 PLLSFIKPDIPITFLRNVTWVIVNLCRNKDPAPPTATIHEILPALNVLIHHTDTNILVDTVWAIS 262
            .||:.|.|.:|||||||:||.:.||||||:|.|....:.:|||||..|:.|.|:.:|.|..||:|
Human   229 HLLALISPTLPITFLRNITWTLSNLCRNKNPYPCDTAVKQILPALLHLLQHQDSEVLSDACWALS 293

  Fly   263 YLTDGGNDQIQMVIESGVVPKLIPLLGNSEVKVQTAALRAVGNIVTGSDEQTQVVLNYDALSYFP 327
            |||||.|.:|..|:.:||:|:|:.|:.:||:.|.|.:||.|||||||:|||||:.::...|:..|
Human   294 YLTDGSNKRIGQVVNTGVLPRLVVLMTSSELNVLTPSLRTVGNIVTGTDEQTQMAIDAGMLNVLP 358

  Fly   328 GLLSHPKEKIRKEAVWFLSNITAGNQSQVQAVINVGLLPKIIENLSKGEFQTQKEAAWAISNLTI 392
            .||.|.|..|:|||.|.|||:.||....:|.::...:||.::..|..|||:.||||.|.::|...
Human   359 QLLQHNKPSIQKEAAWALSNVAAGPCHHIQQLLAYDVLPPLVALLKNGEFKVQKEAVWMVANFAT 423

  Fly   393 SGNREQVFTLIKEGVIPPFCDLLSCQDTQVINVVLDGLNNMLKVADSHVEAVANC--IEECEGLA 455
            ....:|:..|:..||:.|..:||:..|.:::.::||.::.:|:.|:...|....|  |||..|:.
Human   424 GATMDQLIQLVHSGVLEPLVNLLTAPDVKIVLIILDVISCILQAAEKRSEKENLCLLIEELGGID 488

  Fly   456 KIERLQSHENVEIYKLAYEIIDQYFTDEGEQTNM 489
            :||.||.|||.:|.:.|..||:::|   ||.:::
Human   489 RIEALQLHENRQIGQSALNIIEKHF---GEVSDL 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kap-alpha3	NP_001163572.1	IBB	7..88	CDD:280005	27/83 (33%)
		SRP1	8..500	CDD:227396	215/487 (44%)
		ARM	104..224	CDD:237987	67/119 (56%)
		armadillo repeat	104..137	CDD:293788	16/32 (50%)
		armadillo repeat	145..181	CDD:293788	20/35 (57%)
		armadillo repeat	187..222	CDD:293788	17/34 (50%)
		ARM	236..350	CDD:237987	58/113 (51%)
		armadillo repeat	239..264	CDD:293788	12/24 (50%)
		armadillo repeat	272..308	CDD:293788	17/35 (49%)
		armadillo repeat	314..348	CDD:293788	15/33 (45%)
		ARM	315..433	CDD:237987	40/117 (34%)
		armadillo repeat	356..390	CDD:293788	12/33 (36%)
		armadillo repeat	399..433	CDD:293788	9/33 (27%)
		Arm_3	442..485	CDD:292804	18/44 (41%)
KPNA7	XP_016867697.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5064
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54553
OrthoDB	1	1.010	-	-		D1111872at2759
OrthoFinder	1	1.000	-	-		FOG0000157
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.830