Protein Alignment Kap-alpha3 and alphaKap4

DIOPT Version :10

• Sequence 1: NP_731377.1
• Gene: Kap-alpha3 / 41158
• FlyBaseID: FBgn0027338
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_648007.1
• Gene: alphaKap4 / 38675
• FlyBaseID: FBgn0035657
• Length: 442
• Species: Drosophila melanogaster
• Alignment Length: 476
• Identity: 174/476 - (36%)
• Similarity: 261/476 - (54%)
• Gaps: 46/476 - (9%)

  Fly     6 QNRLQNFKNKGKDQDEMRRRRNEVTVELRKNKREETILKRRNVPNLDSNTDEEEQLSSSIDLKKL 70
            |.|.:.|..||::...:|      |:.|.|.|:.| :.|...:.|                  .|
  Fly     2 QKRKRRFLKKGQNLMMLR------TLRLEKAKKAE-LQKELTIYN------------------AL 41

  Fly    71 AKAAADATKPEQQLAAVQAARKLLSSDKNPPINDLIQSDILPILVECLKQHNHTMLQFEAAWALT 135
            .|.                  ||.||:..|.:|.|::|:.:..|||.|...|...::.:||.||.
  Fly    42 TKC------------------KLTSSEVVPDVNKLLKSNTIGNLVESLGHGNKNKIRADAADALA 88

  Fly   136 NIASGTSAQTNEVVAAGAVPLFLQLLNSPAPNVCEQAVWALGNIIGDGPLLRDFVIKHGVVQPLL 200
            :||||:|..:|.:..|||||..::||.||.|.|||:.:.:|||::...|.|||::|:||::|.|:
  Fly    89 HIASGSSEHSNLIAKAGAVPRLIRLLQSPDPEVCEKGILSLGNLLHFAPNLRDYIIRHGLMQKLM 153

  Fly   201 SFIKPDIPIT-FLRNVTWVIVNLCRNKDPAPPTATIHEILPALNVLIHHTDTNILVDTVWAISYL 264
            |.|:.....| .|.:||||:..||.:..|:||. ...||:.|||:::::.:.|:|.|.:.|:..|
  Fly   154 SIIQDKSTCTLMLSHVTWVLRKLCISSQPSPPD-NAAEIIQALNIVLYNPEANVLEDALMAVRNL 217

  Fly   265 TDGGNDQIQMVIESGVVPKLIPLLGNSEVKVQTAALRAVGNIVTGSDEQTQVVLNYDALSYFPGL 329
            .. ||:.|||:::..|||::|.||.:..|.||.|||:|:.||.|||:||.|.:||.:.|.:...|
  Fly   218 AH-GNETIQMLLDFEVVPRIIYLLEHPNVTVQNAALQALINIATGSEEQIQELLNNNLLPHLSAL 281

  Fly   330 LSHPKEKIRKEAVWFLSNITAGNQSQVQAVINVGLLPKIIENLSKGEFQTQKEAAWAISNLTISG 394
            :|:....||.:.:..|.||..||..|..|::|.|||.||:|.|.......:..||..|:.|.|..
  Fly   282 MSNSDPDIRCQVLKLLLNIADGNIFQRHAIMNAGLLHKILECLKADAISLKSAAALTITTLAIDK 346

  Fly   395 NREQVFTLIKEGVIPPFCDLLSCQDTQVINVVLDGLNNMLKVADSHVEAVANCIEECEGLAKIER 459
            ::..:..|:::||||.||:||.||:..:::.|||.|:.||.|..|....|:..||....|..|..
  Fly   347 DKNLLCYLMRQGVIPEFCNLLFCQERDILSNVLDILSTMLDVDPSFSAEVSGIIEWSGALNNIRM 411

  Fly   460 LQSHENVEIYKLAYEIIDQYF 480
            |||.|:.||..:|.:||..||
  Fly   412 LQSSEHEEIAAVARKIIGNYF 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kap-alpha3	NP_731377.1	SRP1	8..500	CDD:227396	173/474 (36%)
		armadillo repeat	104..137	CDD:293788	11/32 (34%)
		armadillo repeat	145..181	CDD:293788	17/35 (49%)
		armadillo repeat	187..222	CDD:293788	15/35 (43%)
		armadillo repeat	239..264	CDD:293788	7/24 (29%)
		armadillo repeat	272..308	CDD:293788	18/35 (51%)
		armadillo repeat	314..348	CDD:293788	9/33 (27%)
		armadillo repeat	356..390	CDD:293788	12/33 (36%)
		armadillo repeat	399..433	CDD:293788	15/33 (45%)
alphaKap4	NP_648007.1	SRP1	45..432	CDD:227396	157/388 (40%)
		armadillo repeat	98..134	CDD:293788	17/35 (49%)
		armadillo repeat	140..176	CDD:293788	15/35 (43%)
		armadillo repeat	192..217	CDD:293788	7/24 (29%)
		armadillo repeat	224..260	CDD:293788	18/35 (51%)
		armadillo repeat	266..300	CDD:293788	9/33 (27%)
		armadillo repeat	308..342	CDD:293788	12/33 (36%)
		armadillo repeat	350..383	CDD:293788	14/32 (44%)