Protein Alignment Kap-alpha3 and kpna3

DIOPT Version :10

• Sequence 1: NP_731377.1
• Gene: Kap-alpha3 / 41158
• FlyBaseID: FBgn0027338
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_958477.2
• Gene: kpna3 / 368640
• ZFINID: ZDB-GENE-030616-541
• Length: 520
• Species: Danio rerio
• Alignment Length: 525
• Identity: 347/525 - (66%)
• Similarity: 408/525 - (77%)
• Gaps: 25/525 - (4%)

  Fly     4 MEQNRLQNFKNKGKDQDEMRRRRNEVTVELRKNKREETILKRRNVPNLDSNTDEEEQLSSS---I 65
            :|.:|:::|||||:|.:.|||.|||||||||||||:|.:||:||||       :||.|..|   .
Zfish     7 LENHRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVP-------QEESLEDSDVDS 64

  Fly    66 DLKK--------LAKAAADATKPEQQLAAVQAARKLLSSDKNPPINDLIQSDILPILVECLKQHN 122
            |.|.        |..|.:|  ....||:||||||||||||:||||:|||:..||||||:||::.:
Zfish    65 DFKGQNVTLDAILQNATSD--NAVVQLSAVQAARKLLSSDRNPPIDDLIKCGILPILVKCLERDD 127

  Fly   123 HTMLQFEAAWALTNIASGTSAQTNEVVAAGAVPLFLQLLNSPAPNVCEQAVWALGNIIGDGPLLR 187
            :..||||||||||||||||||||..||.:.||||||:||:||..||||||||||||||||||..|
Zfish   128 NPSLQFEAAWALTNIASGTSAQTQAVVKSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCR 192

  Fly   188 DFVIKHGVVQPLLSFIKPDIPITFLRNVTWVIVNLCRNKDPAPPTATIHEILPALNVLIHHTDTN 252
            |:||..|||:||||||.|.||||||||||||||||||||||.||..|:.||||||.|||:|||.|
Zfish   193 DYVISLGVVKPLLSFINPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIYHTDIN 257

  Fly   253 ILVDTVWAISYLTDGGNDQIQMVIESGVVPKLIPLLGNSEVKVQTAALRAVGNIVTGSDEQTQVV 317
            ||||||||:||||||||:||||||:|||||.|:|||.:.||||||||||||||||||:|||||||
Zfish   258 ILVDTVWALSYLTDGGNEQIQMVIDSGVVPYLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVV 322

  Fly   318 LNYDALSYFPGLLSHPKEKIRKEAVWFLSNITAGNQSQVQAVINVGLLPKIIENLSKGEFQTQKE 382
            ||.|.|::|..||:||||||.|||||||||||||||.||||||:.||:|.||..|:||:|.||||
Zfish   323 LNCDVLTHFSTLLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKE 387

  Fly   383 AAWAISNLTISGNREQVFTLIKEGVIPPFCDLLSCQDTQVINVVLDGLNNMLKVADSHVEAVANC 447
            ||||||||||||.::||..|:::.||||||:|||.:|:||:.||||||.|:|.:|......:|..
Zfish   388 AAWAISNLTISGRKDQVEYLVQQNVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGEEASTIAEI 452

  Fly   448 IEECEGLAKIERLQSHENVEIYKLAYEIIDQYFT--DEGEQTNMAP-TSDGAQYNFDPHADRLTM 509
            ||||.||.|||.||.|||.:|||||:|||||||:  |..|..::.| .:.|..:|||  :..|..
Zfish   453 IEECGGLEKIENLQQHENEDIYKLAFEIIDQYFSGDDIDEDPSLIPEATQGGTFNFD--SSNLQA 515

  Fly   510 NSFNF 514
            ..|.|
Zfish   516 KEFKF 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kap-alpha3	NP_731377.1	SRP1	8..500	CDD:227396	340/505 (67%)
		armadillo repeat	104..137	CDD:293788	21/32 (66%)
		armadillo repeat	145..181	CDD:293788	26/35 (74%)
		armadillo repeat	187..222	CDD:293788	28/34 (82%)
		armadillo repeat	239..264	CDD:293788	20/24 (83%)
		armadillo repeat	272..308	CDD:293788	29/35 (83%)
		armadillo repeat	314..348	CDD:293788	25/33 (76%)
		armadillo repeat	356..390	CDD:293788	24/33 (73%)
		armadillo repeat	399..433	CDD:293788	20/33 (61%)
kpna3	NP_958477.2	SRP1	2..519	CDD:227396	345/522 (66%)
		HEAT repeat	73..104	CDD:293787	17/32 (53%)
		armadillo repeat	109..142	CDD:293788	21/32 (66%)
		armadillo repeat	150..186	CDD:293788	26/35 (74%)
		armadillo repeat	192..227	CDD:293788	28/34 (82%)
		armadillo repeat	244..269	CDD:293788	20/24 (83%)
		armadillo repeat	277..313	CDD:293788	29/35 (83%)
		armadillo repeat	319..353	CDD:293788	25/33 (76%)
		armadillo repeat	361..395	CDD:293788	24/33 (73%)
		armadillo repeat	404..438	CDD:293788	20/33 (61%)