Protein Alignment Kap-alpha3 and Kpna3

DIOPT Version :10

• Sequence 1: NP_731377.1
• Gene: Kap-alpha3 / 41158
• FlyBaseID: FBgn0027338
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: XP_006252189.1
• Gene: Kpna3 / 361055
• RGDID: 1311339
• Length: 539
• Species: Rattus norvegicus
• Alignment Length: 499
• Identity: 343/499 - (68%)
• Similarity: 402/499 - (80%)
• Gaps: 8/499 - (1%)

  Fly    22 MRRRRNEVTVELRKNKREETILKRRNVPNLDSNTDEE---EQLSSSIDLKKLAKAAADATKPEQQ 83
            |||.|||||||||||||:|.:||:||||..:|..|.:   :..:.::.|:.:.:.|. :..|..|
  Rat    43 MRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQNVTLEAILQNAT-SDNPVVQ 106

  Fly    84 LAAVQAARKLLSSDKNPPINDLIQSDILPILVECLKQHNHTMLQFEAAWALTNIASGTSAQTNEV 148
            |:||||||||||||:||||:|||:|.||||||:||::.::..||||||||||||||||||||..|
  Rat   107 LSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAV 171

  Fly   149 VAAGAVPLFLQLLNSPAPNVCEQAVWALGNIIGDGPLLRDFVIKHGVVQPLLSFIKPDIPITFLR 213
            |.:.||||||:||:||..||||||||||||||||||..||:||..|||:||||||.|.|||||||
  Rat   172 VQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFINPSIPITFLR 236

  Fly   214 NVTWVIVNLCRNKDPAPPTATIHEILPALNVLIHHTDTNILVDTVWAISYLTDGGNDQIQMVIES 278
            |||||||||||||||.||..|:.||||||.|||:|||.|||||||||:||||||||:||||||:|
  Rat   237 NVTWVIVNLCRNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDS 301

  Fly   279 GVVPKLIPLLGNSEVKVQTAALRAVGNIVTGSDEQTQVVLNYDALSYFPGLLSHPKEKIRKEAVW 343
            ||||.|:|||.:.||||||||||||||||||:|||||||||.|.||:||.|||||||||.|||||
  Rat   302 GVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVW 366

  Fly   344 FLSNITAGNQSQVQAVINVGLLPKIIENLSKGEFQTQKEAAWAISNLTISGNREQVFTLIKEGVI 408
            ||||||||||.||||||:.||:|.||..|:||:|.||||||||||||||||.::||..|:::.||
  Rat   367 FLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVI 431

  Fly   409 PPFCDLLSCQDTQVINVVLDGLNNMLKVADSHVEAVANCIEECEGLAKIERLQSHENVEIYKLAY 473
            ||||:|||.:|:||:.||||||.|:|.:|......:|..||||.||.|||.||.|||.:|||||:
  Rat   432 PPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHENEDIYKLAF 496

  Fly   474 EIIDQYFT--DEGEQTNMAP-TSDGAQYNFDPHADRLTMNSFNF 514
            |||||||:  |..|..::.| .:.|..|||||.|: |....|||
  Rat   497 EIIDQYFSGDDIDEDPSLIPEATQGGTYNFDPTAN-LQTKEFNF 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kap-alpha3	NP_731377.1	SRP1	8..500	CDD:227396	334/483 (69%)
		armadillo repeat	104..137	CDD:293788	22/32 (69%)
		armadillo repeat	145..181	CDD:293788	26/35 (74%)
		armadillo repeat	187..222	CDD:293788	28/34 (82%)
		armadillo repeat	239..264	CDD:293788	20/24 (83%)
		armadillo repeat	272..308	CDD:293788	29/35 (83%)
		armadillo repeat	314..348	CDD:293788	28/33 (85%)
		armadillo repeat	356..390	CDD:293788	24/33 (73%)
		armadillo repeat	399..433	CDD:293788	20/33 (61%)
Kpna3	XP_006252189.1	SRP1	43..539	CDD:227396	341/497 (69%)
		armadillo repeat	91..116	CDD:293788	11/25 (44%)
		armadillo repeat	127..160	CDD:293788	22/32 (69%)
		armadillo repeat	168..204	CDD:293788	26/35 (74%)
		armadillo repeat	210..245	CDD:293788	28/34 (82%)
		armadillo repeat	262..287	CDD:293788	20/24 (83%)
		armadillo repeat	295..331	CDD:293788	29/35 (83%)
		armadillo repeat	337..371	CDD:293788	28/33 (85%)
		armadillo repeat	379..413	CDD:293788	24/33 (73%)
		armadillo repeat	422..456	CDD:293788	20/33 (61%)