Protein Alignment Kap-alpha3 and kpna4

DIOPT Version :10

• Sequence 1: NP_731377.1
• Gene: Kap-alpha3 / 41158
• FlyBaseID: FBgn0027338
• Length: 514
• Species: Drosophila melanogaster
• Sequence 2: NP_958462.1
• Gene: kpna4 / 327373
• ZFINID: ZDB-GENE-030131-5584
• Length: 521
• Species: Danio rerio
• Alignment Length: 503
• Identity: 345/503 - (68%)
• Similarity: 404/503 - (80%)
• Gaps: 5/503 - (0%)

  Fly     4 MEQNRLQNFKNKGKDQDEMRRRRNEVTVELRKNKREETILKRRNVPNLDSNTDEEEQLSSSIDLK 68
            :::.||:||||||:|.:.|||:|.||.||||||||:|.:|||||||:.|...|.:..........
Zfish     7 LDKQRLKNFKNKGRDLETMRRQRTEVVVELRKNKRDEHLLKRRNVPHEDICDDSDADGDFRSQNT 71

  Fly    69 KLAKAAADATKPEQ--QLAAVQAARKLLSSDKNPPINDLIQSDILPILVECLKQHNHTMLQFEAA 131
            .|.....:||...|  ||:||||||||||||:||||:|||:|.||||||.||.:.::..||||||
Zfish    72 SLEAIVQNATSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLDRDDNPSLQFEAA 136

  Fly   132 WALTNIASGTSAQTNEVVAAGAVPLFLQLLNSPAPNVCEQAVWALGNIIGDGPLLRDFVIKHGVV 196
            |||||||||||.||..||.:.||||||:||:||..||||||||||||||||||..||:||..|||
Zfish   137 WALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVV 201

  Fly   197 QPLLSFIKPDIPITFLRNVTWVIVNLCRNKDPAPPTATIHEILPALNVLIHHTDTNILVDTVWAI 261
            :||||||.|.||||||||||||:|||||:|||.||..||.||||||.|||||||.|||||||||:
Zfish   202 KPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHTDVNILVDTVWAL 266

  Fly   262 SYLTDGGNDQIQMVIESGVVPKLIPLLGNSEVKVQTAALRAVGNIVTGSDEQTQVVLNYDALSYF 326
            |||||.||:||||||:||:||.|:|||.:.||||||||||||||||||:|||||||||.|||.:|
Zfish   267 SYLTDAGNEQIQMVIDSGIVPYLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALGHF 331

  Fly   327 PGLLSHPKEKIRKEAVWFLSNITAGNQSQVQAVINVGLLPKIIENLSKGEFQTQKEAAWAISNLT 391
            |.||:||||||.|||||||||||||||.||||||:..|:|.||..|.||:|.|||||||||||||
Zfish   332 PALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIILLLDKGDFGTQKEAAWAISNLT 396

  Fly   392 ISGNREQVFTLIKEGVIPPFCDLLSCQDTQVINVVLDGLNNMLKVADSHVEAVANCIEECEGLAK 456
            |||.::||..||::.||||||:||:.:|.||:.||||||:|:||:||...|.|||.||||.||.|
Zfish   397 ISGRKDQVAYLIQQQVIPPFCNLLTVKDAQVVQVVLDGLSNILKMADDEAETVANLIEECGGLEK 461

  Fly   457 IERLQSHENVEIYKLAYEIIDQYFT--DEGEQTNMAPTS-DGAQYNFD 501
            ||:||:|||.:|||||||||||:|:  |..|.:|:.|.: .|..|:|:
Zfish   462 IEQLQNHENEDIYKLAYEIIDQFFSSDDIDEDSNLVPEAIQGGTYSFN 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kap-alpha3	NP_731377.1	SRP1	8..500	CDD:227396	344/496 (69%)
		armadillo repeat	104..137	CDD:293788	22/32 (69%)
		armadillo repeat	145..181	CDD:293788	26/35 (74%)
		armadillo repeat	187..222	CDD:293788	27/34 (79%)
		armadillo repeat	239..264	CDD:293788	21/24 (88%)
		armadillo repeat	272..308	CDD:293788	28/35 (80%)
		armadillo repeat	314..348	CDD:293788	27/33 (82%)
		armadillo repeat	356..390	CDD:293788	23/33 (70%)
		armadillo repeat	399..433	CDD:293788	20/33 (61%)
kpna4	NP_958462.1	SRP1	2..520	CDD:227396	345/503 (69%)
		armadillo repeat	73..98	CDD:293788	12/24 (50%)
		armadillo repeat	109..142	CDD:293788	22/32 (69%)
		armadillo repeat	150..186	CDD:293788	26/35 (74%)
		armadillo repeat	192..227	CDD:293788	27/34 (79%)
		armadillo repeat	244..269	CDD:293788	21/24 (88%)
		armadillo repeat	279..311	CDD:293788	24/31 (77%)
		armadillo repeat	319..355	CDD:293788	29/35 (83%)
		armadillo repeat	361..395	CDD:293788	23/33 (70%)
		armadillo repeat	404..438	CDD:293788	20/33 (61%)