DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG16790 and usb1

DIOPT Version :9

Sequence 1:	NP_649911.1	Gene:	CG16790 / 41155	FlyBaseID:	FBgn0037713	Length:	258	Species:	Drosophila melanogaster
Sequence 2:	XP_009296173.1	Gene:	usb1 / 445066	ZFINID:	ZDB-GENE-040801-197	Length:	278	Species:	Danio rerio

Alignment Length:	285	Identity:	102/285 - (35%)
Similarity:	146/285 - (51%)	Gaps:	37/285 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LVDYGGSSSSASEDED-------------CTENIQTPALITLKRPALPKAATLLGPKKPKPE--- 51
            :|:|   |||:||:|.             .||...:.||...........::.|.|:.|.||
Zfish     2 IVNY---SSSSSEEESGSSSSPSGKRQKLDTETSNSEALDHGSAQRKVCKSSHLTPRLPLPESVK 63

  Fly    52 EFVEDV----VDDPAEHGGRMRSFKHERGNWATYVYVPATACVDQLEEF---QTEAIARLEPH-L 108
            |...|.    .|...|||||:|||:||||||||||:.|    .|..|.|   ..:.:|..|.| :
Zfish    64 EMFRDSEELWTDKSEEHGGRLRSFQHERGNWATYVFFP----YDPEEAFLEVLNKMMAAAEAHDI 124

  Fly   109 ELQPNESLHLSLSRTVVLQYHQIDEFSRSLQSALNSSAGFAATLQGLRIYTNEERTRTFIAAPLD 173
            .|..:|..|||||:||||::|.|..|.:|::::|.....|......|::|:|.|:||||:...:.
Zfish   125 PLTVSEEFHLSLSKTVVLRHHWIQPFVQSIRTSLTHFQKFYCVAYKLKVYSNAEKTRTFLGMEVS 189

  Fly   174 AAFVEKMTAILQPIDQVMLDYRLQQFYDPASFHVSLLWCVGDQ-ETLLNEKLTELKELLDDQD-- 235
            .. ...:..:.:.:|:.|.::.|..||:..|||:||.|||||| |.|....|.||:.|:|..:
Zfish   190 TG-TPHLLELSKIVDETMKEFNLSTFYEDPSFHISLAWCVGDQTERLKKACLLELQGLIDAHEDG 253

  Fly   236 --KLCLAVNEVHLKCGNKDFTYSLK 258
              ...|..||:..|.|||.|.:.|:
Zfish   254 PFHARLNCNELRCKTGNKVFVFPLQ 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16790	NP_649911.1	HVSL	34..254	CDD:286792	88/235 (37%)
usb1	XP_009296173.1	HVSL	56..276	CDD:286792	87/224 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590880
Domainoid	1	1.000	138	1.000	Domainoid score	I4827
eggNOG	1	0.900	-	-		E1_KOG3102
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11611
Inparanoid	1	1.050	146	1.000	Inparanoid score	I4400
OMA	1	1.010	-	-		QHG52902
OrthoDB	1	1.010	-	-		D1507496at2759
OrthoFinder	1	1.000	-	-		FOG0007343
OrthoInspector	1	1.000	-	-		oto40287
orthoMCL	1	0.900	-	-		OOG6_103799
Panther	1	1.100	-	-	LDO	PTHR13522
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1612
SonicParanoid	1	1.000	-	-		X5460
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800