Protein Alignment CG16789 and SAP1

DIOPT Version :10

• Sequence 1: NP_649910.3
• Gene: CG16789 / 41154
• FlyBaseID: FBgn0037712
• Length: 831
• Species: Drosophila melanogaster
• Sequence 2: NP_010966.1
• Gene: SAP1 / 856771
• SGDID: S000000849
• Length: 897
• Species: Saccharomyces cerevisiae
• Alignment Length: 690
• Identity: 142/690 - (20%)
• Similarity: 250/690 - (36%)
• Gaps: 215/690 - (31%)

  Fly   164 GWLEEHELEETVTTEIEAIRMLQMHERARQGRLRAHFMKEIRILKEKGKSEERTEKERSDSGLLA 228
            |.|:.|.||.:.|.:...||..|:          :..||...:...||.....|...:|
Yeast   357 GALKPHSLETSTTMDSSKIRNPQI----------SKLMKNNHVPYLKGTKSTPTLITKS------ 405

  Fly   229 AMKIQKMWRGHTARRITRRRKMEEMIL-------IGMLPPPPAVV---KERAEKLEKLQHNEKRY 283
                       |...|||.:...:.|:       ...|..|.:|:   |..|...:::.:::|..
Yeast   406 -----------TPTFITRSKSNTKPIIKSNASSPTSSLTVPNSVIQKPKTAAMAAKRVLNSKKVA 459

  Fly   284 QAQAFYGKEFEERQNALKEEIRAKHGASMKEDIADEIRAWVKDCYDKTGKLPDFPSEDQGGSLHI 348
            ...|.         |..|     |....:|               .||.|:|:  |..:..|.|.
Yeast   460 SNPAL---------NTTK-----KSHPILK---------------SKTAKVPN--SSSKKTSSHP 493

  Fly   349 FSRPGTESE-HSRSSARSSKESRK-----TKDKSKSPARSGDLNVNENQDEEVSFQPAP--SVCL 405
             |||.:.|: :|..::::.|.|:.     :|...|.||:.   .:...:.|:|..:.|.  :..|
Yeast   494 -SRPVSNSKPYSHGASQNKKPSKNQTTSMSKTNRKIPAQK---KIGSPKIEDVGTEDATEHATSL 554

  Fly   406 PDIRAEIDLFNDTWRDKDETGVLSQAAYEDMIYSDKYQEVELEFRRAV--------DDVMRQEIE 462
            .:.|.|.::      ||.   ||.:...:::|  |..|.|:.:..:.:        |:|...:|.
Yeast   555 NEQREEPEI------DKK---VLREILEDEII--DSLQGVDRQAAKQIFAEIVVHGDEVHWDDIA 608

  Fly   463 LLQTAVGKKVKKSSKKTRRSGKKSKKKKEKDLTPDRTTESLYEELVTNGIIRKYPELRLKQFLGD 527
            .|::|                                ..||.|.:|       ||.||...|.|
Yeast   609 GLESA--------------------------------KYSLKEAVV-------YPFLRPDLFRG- 633

  Fly   528 KALTARIGTNPSPGDIRQILTEYCILPLGSDAIHNCTPLIRSILLAGPKGSGKKALLHAICTEVG 592
                           :|:                   | :|.:||.||.|:||..|..|:.||..
Yeast   634 ---------------LRE-------------------P-VRGMLLFGPPGTGKTMLARAVATESH 663

  Fly   593 AVLFDLTPANIVGKYPGKSGLIMLIHLVLKVSRLLQPAVIFMGDAERPFMKKIPKTDRTDPKRLK 657
            :..|.::.:::..||.|:|.  .|:..:..:::.|.|::||:.:.:.....:..:.:....:|:|
Yeast   664 STFFSISASSLTSKYLGESE--KLVRALFAIAKKLSPSIIFVDEIDSIMGSRNNENENESSRRIK 726

  Fly   658 KDLPKLIKNIA------------------PED--RVVFIGTSNLPWEADQKLLQSVYNRFI---Y 699
            .:......:::                  .||  ||:.:..:||||..|    ::...||:   |
Yeast   727 NEFLVQWSSLSSAAAGSNKSNTNNSDTNGDEDDTRVLVLAATNLPWSID----EAARRRFVRRQY 787

  Fly   700 IPRPDYGAMSHAWKTLLHDYSGGISNLDTSAMAKISDGYTIGSI-----DACLKEVMTCKRKLQL 759
            ||.|:.......:|.||......::..|...:.||::||:...|     ||.:..:.....|| |
Yeast   788 IPLPEDQTRHVQFKKLLSHQKHTLTESDFDELVKITEGYSGSDITSLAKDAAMGPLRDLGDKL-L 851

  Fly   760 RTQ-----PLTNAELINVLCSRDP-VYREEEEAFESWWSK 793
            .|:     |:...:..|.|....| |.::....:|.|.|:
Yeast   852 ETEREMIRPIGLVDFKNSLVYIKPSVSQDGLVKYEKWASQ 891

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16789	NP_649910.3	DUF5401	<131..>307	CDD:375164	29/152 (19%)
		SpoVK	443..773	CDD:440232	75/370 (20%)
		P-loop containing Nucleoside Triphosphate Hydrolases	542..700	CDD:476819	37/180 (21%)
SAP1	NP_010966.1	Herpes_BLLF1	<353..543	CDD:282904	50/247 (20%)
		McrB	<539..>659	CDD:441011	41/205 (20%)
		RecA-like_VPS4-like	607..788	CDD:410917	50/261 (19%)
		AAA_lid_3	815..850	CDD:465537	8/34 (24%)
		Vps4_C	<847..893	CDD:462762	12/46 (26%)