Protein Alignment CG16789 and PCH2

DIOPT Version :10

• Sequence 1: NP_649910.3
• Gene: CG16789 / 41154
• FlyBaseID: FBgn0037712
• Length: 831
• Species: Drosophila melanogaster
• Sequence 2: NP_009745.2
• Gene: PCH2 / 852484
• SGDID: S000000390
• Length: 564
• Species: Saccharomyces cerevisiae
• Alignment Length: 594
• Identity: 122/594 - (20%)
• Similarity: 198/594 - (33%)
• Gaps: 188/594 - (31%)

  Fly   302 EEIRAKH-GASMKE-------DIADEIRAWVKDCYDKTGKLPDFPSE--------------DQGG 344
            |:|.:.| |:..|:       :..:.::|.||      .||..||.:              :..|
Yeast    25 EQISSLHSGSDSKQNSNKKLGEFLNLLKAVVK------RKLESFPKDRLKTSIITGQELMREGQG 83

  Fly   345 SLHIFSRPGTESEH-SRSSARSSKESRKTKDKSKSPARSGDLN-VNENQDE----------EVSF 397
            |:.|...|....:| .||.|:....        :..:.:|.:| |||.||.          .:..
Yeast    84 SIEIKDPPTEAQQHLIRSLAKVLLH--------QFSSINGKVNTVNEGQDNLFLSLFVKKISIEQ 140

  Fly   398 QPAPSVCLP-DIRAEIDLFN--DTWRDKDETGVLSQAAY------EDMIY--------------- 438
            |....|.:. :...:|:|..  |:..|.:||.  ....|      |.:||
Yeast   141 QSTSHVSIKLNFHEKINLGQHIDSILDSEETN--ESDTYHMGSVDEFIIYPFCCLEEQDELKNGS 203

  Fly   439 --SDKYQEVELEFRRAVDDVMRQE-IELLQTAVGKKVKKSSKKTRRSGKKSKKKKEKDLTPDRTT 500
              |.::.:::||...  ||....| :.....:||......||:|......|       ..|..|.
Yeast   204 ILSTEFDKIDLELDE--DDGFEGETLNNCINSVGNFDIPLSKQTLNLVNIS-------YLPGTTF 259

  Fly   501 ESLYEELVTNGIIRKYPELRLKQFLGDKALTARIGTNPSPGDIRQILTEYCILPLGSDAIHNCTP 565
            |..:|.|.....|::    ||..:   ..::.:|......||..|               .:.|.
Yeast   260 EGQWESLYFGNNIKE----RLYSY---ATISLKIARFKQTGDSNQ---------------EDITT 302

  Fly   566 LI---RSILLAGPKGSGKKALLHAIC-----------------TEVGAVLFDLTPANIVGKYPGK 610
            ||   :.:|:.||.|:||..|..|:|                 |....::.:|:.|.|..|:.|:
Yeast   303 LITNNKLLLVHGPPGTGKTTLCKALCQKLSVRREFSDGSDTIDTNYKGIIIELSCARIFSKWFGE 367

  Fly   611 SG-----LIMLIHLVLKVSR-------LLQPAVIFMGDAERPFMKKIPKTDRTDPKRLKKDLPKL 663
            |.     :...|..:|||:.       ||...|..:..:......   :.:.||..|:...|...
Yeast   368 SSKNISIVFKDIEELLKVNEGRGIFICLLIDEVEAIASSRTNLSS---RNESTDGIRVVNTLLTQ 429

  Fly   664 IKNIAPEDRVVFIGTSNLPWEADQKLLQSVYNRFI-------YIPRPDYGAMSHAWKT------- 714
            :..:......:.:.|||        ||.|:.:.|:       |:..|....:.|..|.
Yeast   430 LDRLKKYHNFLALATSN--------LLDSLDDAFVDRADGVFYVGNPTAEGILHILKVCIEEMIT 486

  Fly   715 ----LLHDYSGGIS--NLDTSAMAKIS--------DGYTIGSID-ACLKEVMTCKRKLQLRTQPL 764
                |.|..|.|:.  |.....:.||:        .|.||..:. .||.|        ..||.|:
Yeast   487 SGIILFHARSTGVKFFNKYQDILRKIAIKCSTVDISGRTIRKLPLMCLSE--------YFRTFPV 543

  Fly   765 TNAELINVL 773
            .:.|.:..|
Yeast   544 DDDEFVLAL 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16789	NP_649910.3	DUF5401	<131..>307	CDD:375164	2/4 (50%)
		SpoVK	443..773	CDD:440232	81/391 (21%)
		P-loop containing Nucleoside Triphosphate Hydrolases	542..700	CDD:476819	39/196 (20%)
PCH2	NP_009745.2	P-loop containing Nucleoside Triphosphate Hydrolases	248..465	CDD:476819	50/256 (20%)