Protein Alignment CG16789 and AFG2

DIOPT Version :10

• Sequence 1: NP_649910.3
• Gene: CG16789 / 41154
• FlyBaseID: FBgn0037712
• Length: 831
• Species: Drosophila melanogaster
• Sequence 2: NP_013501.1
• Gene: AFG2 / 851113
• SGDID: S000004389
• Length: 780
• Species: Saccharomyces cerevisiae
• Alignment Length: 799
• Identity: 151/799 - (18%)
• Similarity: 269/799 - (33%)
• Gaps: 202/799 - (25%)

  Fly    26 ERQHQDVETTVATMNAAVGSVAADADAKALLQSSLYEFYLRYICLSNRLEDVYDNMIQPQKRQLV 90
            |..|.....|::|...:||::.. .|...|.::.:...|...:.:.: |:..  |:::..:.:::
Yeast    88 EEVHPVNVITLSTTIRSVGNLIL-GDRLELKKAQVQPPYATKVTVGS-LQGY--NILECMEEKVI 148

  Fly    91 RKLLD----ACLGRVVE-LKH-------DLVNIDLMEFSYNDEVVERLRLTPMETEL-----RIP 138
            :||||    ...|.:.: ||.       |:|..|..:.|..|.....|.:..|...|     ..|
Yeast   149 QKLLDDSGVIMPGMIFQNLKTKAGDESIDVVITDASDDSLPDVSQLDLNMDDMYGGLDNLFYLSP 213

  Fly   139 RYFLRERQQELEFRKKTMHEILTKLGWLEEHELEETVT--------TEIEAIRM---LQMHERAR 192
            .:..|:....:.|.|:|...        .::.|.|.::        .|||:::.   :.:|
Yeast   214 PFIFRKGSTHITFSKETQAN--------RKYNLPEPLSYAAVGGLDKEIESLKSAIEIPLH---- 266

  Fly   193 QGRLRAHFMKEIRILKEKGKSEERTEKERSDSGLLAAMKIQKMWRGHTARRITRRRKMEEMILIG 257
            |..|.:.|          |.|..|........|....|.::.:.....|..:|
Yeast   267 QPTLFSSF----------GVSPPRGILLHGPPGTGKTMLLRVVANTSNAHVLT------------ 309

  Fly   258 MLPPPPAVVK---ERAEKLEKLQHNEKRYQAQAFYGKEFE----ERQNALKEEIRAKHGASMKED 315
             :..|..|.|   |....|..:.:..::||....:..|.:    .|.|....|:.::..|::
Yeast   310 -INGPSIVSKYLGETEAALRDIFNEARKYQPSIIFIDEIDSIAPNRANDDSGEVESRVVATL--- 370

  Fly   316 IADEIRAWVKDCYDKTGKLPDFPSEDQGGSLH-IFSRPGTESEHSRSSARSSKESRKTKDKSKSP 379
                  ..:.|.....||:....:.::..|:. ...|||
Yeast   371 ------LTLMDGMGAAGKVVVIAATNRPNSVDPALRRPG-------------------------- 403

  Fly   380 ARSGDLNVNENQDEEVSFQPAPSVCLPDIRAEIDLFNDTW-RDKDETGVLSQAAYEDMIYSDKYQ 443
                      ..|:||      .:.:||:.|..|:....: |...:..||...|.: .|.|..:.
Yeast   404 ----------RFDQEV------EIGIPDVDARFDILTKQFSRMSSDRHVLDSEAIK-YIASKTHG 451

  Fly   444 EVELEF----RRAVDDVMRQEIELLQTAVG--KKVKKSSKKTRRSGKKSKKKKEKDLTPDRTTES 502
            .|..:.    |.:|       ::.:|..:|  ..:.|.|.|..   .|..:....|:.|....|
Yeast   452 YVGADLTALCRESV-------MKTIQRGLGTDANIDKFSLKVT---LKDVESAMVDIRPSAMRE- 505

  Fly   503 LYEELVTNGIIRKYPELRLKQFLGDKALTARIGTNPSPGDIRQILTEYCILPLGSDAIHNCTPL- 566
                     |..:.|::......|.:.|..:             :.|...|||  :|......|
Yeast   506 ---------IFLEMPKVYWSDIGGQEELKTK-------------MKEMIQLPL--EASETFARLG 546

  Fly   567 ---IRSILLAGPKGSGKKALLHAICTEVGAVLFDLTPANIVGKYPGKSGLIMLIHLVLKVSRLLQ 628
               .:.:||.||.|..|.....|:.||.|.....:....|..||.|:|.  ..|..:.:.:|...
Yeast   547 ISAPKGVLLYGPPGCSKTLTAKALATESGINFLAVKGPEIFNKYVGESE--RAIREIFRKARSAA 609

  Fly   629 PAVIFMGDAERPFMKKIPKTDRTDPKRLKKDLPKLIKNIAPEDR---VVFIGTSNLPWEADQKLL 690
            |::||..:.:    ...|..|.:........|..|:..|...:.   ||.:..:|.|.|.|..||
Yeast   610 PSIIFFDEID----ALSPDRDGSSTSAANHVLTSLLNEIDGVEELKGVVIVAATNRPDEIDAALL 670

  Fly   691 Q-SVYNRFIYIPRPDYGAMSHAWKTLLHDYSGGISNLDTSAMAKISDGYTIGSIDACLKEVMTCK 754
            : ...:|.||:..||..|.....|.....::...|.:|...:|..::||:...:      |:.|:
Yeast   671 RPGRLDRHIYVGPPDVNARLEILKKCTKKFNTEESGVDLHELADRTEGYSGAEV------VLLCQ 729

  Fly   755 R-------------KLQLR 760
            .             |::||
Yeast   730 EAGLAAIMEDLDVAKVELR 748

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16789	NP_649910.3	DUF5401	<131..>307	CDD:375164	34/198 (17%)
		SpoVK	443..773	CDD:440232	72/345 (21%)
		P-loop containing Nucleoside Triphosphate Hydrolases	542..700	CDD:476819	41/165 (25%)
AFG2	NP_013501.1	CDC48	51..773	CDD:273521	151/799 (19%)