Protein Alignment CG16789 and Iqca1

DIOPT Version :10

• Sequence 1: NP_649910.3
• Gene: CG16789 / 41154
• FlyBaseID: FBgn0037712
• Length: 831
• Species: Drosophila melanogaster
• Sequence 2: NP_001355651.1
• Gene: Iqca1 / 74918
• MGIID: 1922168
• Length: 838
• Species: Mus musculus
• Alignment Length: 868
• Identity: 325/868 - (37%)
• Similarity: 530/868 - (61%)
• Gaps: 71/868 - (8%)

  Fly     1 MSSTYFNDIWHQSQHECELLSTIDYERQHQDVETTVATMNAAVGSVAADADAKALLQSSLYEFYL 65
            ||:..:|.:|||:|   |.|::: .:::.|.:....|.              |.|:...|..||:
Mouse     1 MSNLMYNKMWHQTQ---EALNSL-LDKEFQKMSEPQAN--------------KVLVFQMLATFYI 47

  Fly    66 RYICLSNRLEDVYDNMIQPQKRQLVRKLLDACLGRVVELKHDLVNIDLMEFSYNDEVVERLRLTP 130
            .|:.:...:|:|||.::.||||.|:||:||..:||::|||:::|.:::.||.|.|::::.|:|:|
Mouse    48 NYVQIFRNMENVYDQIVHPQKRMLIRKVLDGVMGRILELKNEMVELEMTEFHYFDDILQDLKLSP 112

  Fly   131 METELRIPRYFLRERQQELEFRKKTMHEILTKLGW-LEEHELEETVTTEIEAIRMLQMHERARQG 194
            .:.::.||||||:||.:.::.|:|.:..|||:.|. |......:::..| ||::::|:.||||||
Mouse   113 QQLDVPIPRYFLKERLEVIKGREKILARILTECGLNLPVKYAAKSIALE-EAVKLIQIAERARQG 176

  Fly   195 RLRAHFMKEIRILKEKGKSEERTEKERSDSGLLAAMKIQKMWRG-HTARRITRRRKMEEMILIGM 258
            ||||.|||:| .|:|....|.:....|.....|||::|||:||| |..::..:.|: |||:.:||
Mouse   177 RLRALFMKQI-FLQECRAKEMKLLGHRLLDTKLAALQIQKVWRGFHQCKKTVKERE-EEMVFLGM 239

  Fly   259 LPPP------PAVVKERAEKLEKLQHNEKRYQAQAFYGKEFEERQNALKEEIRAKHGASMKEDIA 317
            .|.|      .|:|:.:       |....|.:.|..:.::::|....:||:::...|..:||.:.
Mouse   240 KPSPLFNEVSDAIVQSK-------QVTNLRDEVQLKHEQDYQEALVNIKEDLKMLEGPDIKEHLQ 297

  Fly   318 DEIRAWVKDCYDKTGKLPDFPSEDQGGSLHIFSRP----------GTESEHSRSSARSSKESRKT 372
            |:||.|..:|.:.||..||:|:|:.|||..|||..          .|:.|..:...:..||.::.
Mouse   298 DQIRQWFIECRNLTGTFPDYPNEEDGGSALIFSNKTPEQVMGDIIATQEEEEKLKKKKKKEDKEN 362

  Fly   373 K----DKSKSPARSGDLNVNEN--QDEEVSFQPAPSVCLPDIRAEIDLFNDTWRDKDETGVLSQA 431
            |    .|.|...:...:::.|.  :||:..::.:||:.|..:.....|:.|.|.:|||:....|.
Mouse   363 KGKKGKKEKKEKKEKKVSLKEKAMKDEDEEWKMSPSLFLQLMEEGNSLYKDIWLNKDESWNFPQD 427

  Fly   432 AYEDMIYSDKYQEVELEFRRAVDDVMRQEIELLQTAVGKKV------KKSSKKTR-RSGKKSKK- 488
            ...::|..:|.:|:|:|.|..||::||||::.|:.||.:::      ||..||.: |.|::.|:
Mouse   428 YDPELIKEEKRKELEMEIRVQVDELMRQELKNLKLAVNREMEIPPRQKKGKKKNKGRKGRRGKRG 492

  Fly   489 KKEKDLTPDRTTESLYEELVTNGIIRKYPELRLKQFLGDKALTA----RIGTNPSPG--DIRQIL 547
            |||||||.|||.||||:|||..|::.:..::.|..::|:.:...    ::...|.|.  |:||::
Mouse   493 KKEKDLTADRTIESLYQELVEKGLLIQALKVNLSDYIGEYSYLGTTLRQVAIEPMPSLLDVRQLI 557

  Fly   548 TEYCILPLGSDAIHNCTPLIRSILLAGPKGSGKKALLHAICTEVGAVLFDLTPANIVGKYPGKSG 612
            |.|.||||||..:|...||::|:|||||.|.|||.|:||||||.||.||:|:..||.||||||:|
Mouse   558 TLYGILPLGSAEVHERAPLVKSLLLAGPSGVGKKMLVHAICTETGANLFNLSALNIAGKYPGKTG 622

  Fly   613 LIMLIHLVLKVSRLLQPAVIFMGDAERPFMKKIPKTD-RTDPKRLKKDLPKLIKNIAPEDRVVFI 676
            |.|:||||.||:|.|||:|:::.|.|:.|.||:|:.: |.:|||||:.||||:|.:.|:||::.:
Mouse   623 LQMMIHLVFKVARQLQPSVVWIQDTEKTFYKKVPQAEKRFEPKRLKRYLPKLLKLLKPDDRILIV 687

  Fly   677 GTSNLPWEADQKLLQSVYNRFIYIPRPDYGAMSHAWKTLLHDYSGGISN-LDTSAMAKISDGYTI 740
            ||::.|::|:.:....||.:.|.:|||||.:....||.::....|.::| |:.|.::|::||:|.
Mouse   688 GTTHRPFDAELQPFCRVYQKIILVPRPDYASRYVLWKEIILRNGGKLTNSLNISCLSKVTDGFTQ 752

  Fly   741 GSIDACLKEVMTCKRKLQLRTQPLTNAELINVLCSRDPVYREEEEAFESWWSKTPLGRRRQRFLE 805
            |.|...:|:|:|.:|..|...:|||..|.|.::.:.:||||||||:|::|::|||||::|...|.
Mouse   753 GQIVQVIKDVLTERRLRQQAHKPLTAIEFITMMTNMNPVYREEEESFKNWYAKTPLGKKRVLSLT 817

  Fly   806 LEEERLLEEQAQAAKQGNGNKKK 828
            :..:   |::....|:|...|||
Mouse   818 VGNK---EKEKDKGKKGKRGKKK 837

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16789	NP_649910.3	DUF5401	<131..>307	CDD:375164	63/183 (34%)
		SpoVK	443..773	CDD:440232	154/345 (45%)
		P-loop containing Nucleoside Triphosphate Hydrolases	542..700	CDD:476819	85/158 (54%)
Iqca1	NP_001355651.1	P-loop containing Nucleoside Triphosphate Hydrolases	552..711	CDD:476819	85/158 (54%)