Protein Alignment CG16789 and FIGN

DIOPT Version :10

• Sequence 1: NP_649910.3
• Gene: CG16789 / 41154
• FlyBaseID: FBgn0037712
• Length: 831
• Species: Drosophila melanogaster
• Sequence 2: XP_047300819.1
• Gene: FIGN / 55137
• HGNCID: 13285
• Length: 785
• Species: Homo sapiens
• Alignment Length: 596
• Identity: 131/596 - (21%)
• Similarity: 226/596 - (37%)
• Gaps: 131/596 - (21%)

  Fly   260 PPPPAVVK--ERAEKLEKLQHNEKRYQAQAFYGKEFEERQNALKEEIRAKHGASMKEDIADEIRA 322
            |||||:|.  .....|....:....|..|...|..:            :..||...
Human   253 PPPPALVPGYNGTSNLSSYSYPSASYPPQTAVGSGY------------SPGGAPPP--------- 296

  Fly   323 WVKDCYDKTG----------KLPDFPSEDQGGSLHIFSRPGTESEHSRSSARSSKESRKTKDKSK 377
              ...|..:|          .:|.:..:..|      ..|...|..:.|||.|.|.      |:.
Human   297 --PSAYLPSGIPAPTPLPPTTVPGYTYQGHG------LTPIAPSALTNSSASSLKR------KAF 347

  Fly   378 SPARSGDLNV---NENQDEEVSFQPAPSVCLPDIRAEIDLFNDTWR----DKD-ETGVLSQAAYE 434
            ..|..||::.   |.:..::.|.| :|...:||     :..::|.|    |:. ||..|:....:
Human   348 YMAGQGDMDSSYGNYSYGQQRSTQ-SPMYRMPD-----NSISNTNRGNGFDRSAETSSLAFKPTK 406

  Fly   435 DMIYSDKYQEVELEFRRAVDDVMRQEIELLQTAVGKKVKKSSKKTR------------------- 480
            .::.|::.::...:..||:..   ......:.::|.:..:|..|..
Human   407 QLMSSEQQRKFSSQSSRALTP---PSYSTAKNSLGSRSSESFGKYTSPVMSEHGDEHRQLLSHPM 468

  Fly   481 -----RSGKKSKKKKEKDLTPDRTTESLYEELVTNGIIRKYPELRLKQFLGDKALTARIGTNPSP 540
                 |:...|....::.|   :.|::...:||||.||.:.|.:......|...
Human   469 QGPGLRAATSSNHSVDEQL---KNTDTHLIDLVTNEIITQGPPVDWNDIAGLDL----------- 519

  Fly   541 GDIRQILTEYCILP-LGSDAIHNCTPLIRSILLAGPKGSGKKALLHAICTEVGAVLFDLTPANIV 604
              ::.::.|..:.| |.|||....|.|.|||||.||:|:||..|...|.:::||..|.:..:.:|
Human   520 --VKAVIKEEVLWPVLRSDAFSGLTALPRSILLFGPRGTGKTLLGRCIASQLGATFFKIAGSGLV 582

  Fly   605 GKYPGKSGLIMLIHLVLKVSRLLQPAVIFMGDAERPFMKKIPKTDRTDPKRLKKDLPKLIKNI-- 667
            .|:.|::..|  ||....|:|..||:|||:.|.:.....:: ..:.:...|::.:....:..:
Human   583 AKWLGEAEKI--IHASFLVARCRQPSVIFVSDIDMLLSSQV-NEEHSPVSRMRTEFLMQLDTVLT 644

  Fly   668 APEDRVVFIGTSNLPWEADQKLLQSVYNRFIYIPRPDYGAMSHAWKTLL--HDY----------- 719
            :.||::|.|..::.|.|.|:.|.:....|.: ||.||..|.......||  |:|
Human   645 SAEDQIVVICATSKPEEIDESLRRYFMKRLL-IPLPDSTARHQIIVQLLSQHNYCLNDKEFALLV 708

  Fly   720 --SGGISNLDTSAMAKISDGYTIGSIDACLKEVMTCKRKLQLRTQPLTNAELINVLCSRDPVYRE 782
              :.|.|.||   :|.:.....:|.:.|.....::.....|||  |:|..:..|..|...|...:
Human   709 QRTEGFSGLD---VAHLCQEAVVGPLHAMPATDLSAIMPSQLR--PVTYQDFENAFCKIQPSISQ 768

  Fly   783 EEEAFESWWSK 793
            :|......|:|
Human   769 KELDMYVEWNK 779

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG16789	NP_649910.3	DUF5401	<131..>307	CDD:375164	10/48 (21%)
		SpoVK	443..773	CDD:440232	86/371 (23%)
		P-loop containing Nucleoside Triphosphate Hydrolases	542..700	CDD:476819	47/160 (29%)
FIGN	XP_047300819.1	RecA-like_fidgetin	513..676	CDD:410931	48/179 (27%)
		AAA_lid_3	701..>732	CDD:465537	6/33 (18%)
		Vps4_C	<749..782	CDD:462762	8/31 (26%)